biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
form
buffered aqueous glycerol solution
species reactivity
rat, human, mouse
technique(s)
western blot: 1:1,000
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... MAPT(4137)
mouse ... Mapt(17762)
rat ... Mapt(29477)
Immunogen
chemically synthesized phosphopeptide derived from the region of human tau that contains serine422.
Physical form
Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, with 50% glycerol, 1.0 mg/ml BSA (IgG and protease free), 50% glycerol and 0.05% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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T Bussière et al.
Acta neuropathologica, 97(3), 221-230 (1999-03-25)
Neuronal inclusions with bundles of abnormal filaments made of tau polymers are found in numerous diseases with neurofibrillary degeneration. Tau proteins are the basic components of paired helical filaments (PHF) in Alzheimer's disease (AD), and are abnormally phosphorylated. A disease-specific
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