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Merck
CN

T8326

MonoclonalAnti-Tau-410, C-terminal 小鼠抗

clone DC39, purified immunoglobulin, buffered aqueous solution

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关于此项目

UNSPSC Code:
12352203
MDL number:
MFCD09039234

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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

DC39, monoclonal

form

buffered aqueous solution

mol wt

antigen 45-68 kDa

species reactivity

human, mouse, pig, rat, rabbit

technique(s)

immunohistochemistry: 1:2,000, indirect ELISA: 1:4,000, indirect immunofluorescence: 1:2,000, radioimmunoassay: 1:2,000, western blot: 1:2,000 using whole brain tissue

isotype

IgG1

UniProt accession no.

P10636

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... MAPT(4137)
mouse ... mt-Ta(17726)

Immunogen

human tau isoform 39 (Tau-410).

Biochem/physiol Actions

Recognizes C-terminus of Tau protein. Reacts with the non-phosphorylated as well as phosphorylated tau isoforms.

Physical form

Solution in serum-free DMEM (without sodium pyruvate and sodium bicarbonate) containing 0.1% thimerosal as a preservative.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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pictograms

Health hazard
GHS08

signalword

Warning

hcodes

H373

Hazard Classifications

STOT RE 2

target_organs

Kidney

存储类别

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
011M1175
060M1660
129K1205
118K1212
028K1164

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Do you offer a positive control for use with Product T8326, Monoclonal Anti-Tau-410, C-terminal antibody?

    We offer T0451.

  6. What is the difference between the various Tau isoforms?

    The human brain tau isoforms range from 352 to 441 amino acids. They differ in whether they contain three or four tubulin binding domains (repeats, R) of 31 or 32 amino acids, each in the C-terminal half, and two, one , or no inserts of 29 amino acids each in the N-terminal portion of the molecule.

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

A D Alonso et al.
The Journal of biological chemistry, 276(41), 37967-37973 (2001-08-10)
The microtubule-associated protein tau is a family of six isoforms that becomes abnormally hyperphosphorylated and accumulates in neurons undergoing neurodegeneration in the brains of patients with Alzheimer disease (AD). We investigated the isoform-specific interaction of normal tau with AD hyperphosphorylated

相关内容

Data Sheet - T8326

Instructions

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