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Merck
CN

T8326

Sigma-Aldrich

MonoclonalAnti-Tau-410, C-terminal 小鼠抗

clone DC39, purified immunoglobulin, buffered aqueous solution

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关于此项目

MDL编号:
MFCD09039234
UNSPSC代码:
12352203

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生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

DC39, monoclonal

表单

buffered aqueous solution

分子量

antigen 45-68 kDa

种属反应性

human, mouse, pig, rat, rabbit

技术

immunohistochemistry: 1:2,000
indirect ELISA: 1:4,000
indirect immunofluorescence: 1:2,000
radioimmunoassay: 1:2,000
western blot: 1:2,000 using whole brain tissue

同位素/亚型

IgG1

UniProt登记号

P10636

运输

dry ice

储存温度

−20°C

基因信息

human ... MAPT(4137)
mouse ... mt-Ta(17726)

免疫原

human tau isoform 39 (Tau-410).

生化/生理作用

Recognizes C-terminus of Tau protein. Reacts with the non-phosphorylated as well as phosphorylated tau isoforms.

外形

Solution in serum-free DMEM (without sodium pyruvate and sodium bicarbonate) containing 0.1% thimerosal as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形图

Health hazard
GHS08

警示用语：

Warning

危险声明

H373

预防措施声明

P260 - P314 - P501

危险分类

STOT RE 2

靶器官

Kidney

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
011M1175
060M1660
129K1205
118K1212
028K1164

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  4. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  5. Do you offer a positive control for use with Product T8326, Monoclonal Anti-Tau-410, C-terminal antibody?

    We offer T0451.

  6. What is the difference between the various Tau isoforms?

    The human brain tau isoforms range from 352 to 441 amino acids. They differ in whether they contain three or four tubulin binding domains (repeats, R) of 31 or 32 amino acids, each in the C-terminal half, and two, one , or no inserts of 29 amino acids each in the N-terminal portion of the molecule.

  7. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

A D Alonso et al.
The Journal of biological chemistry, 276(41), 37967-37973 (2001-08-10)
The microtubule-associated protein tau is a family of six isoforms that becomes abnormally hyperphosphorylated and accumulates in neurons undergoing neurodegeneration in the brains of patients with Alzheimer disease (AD). We investigated the isoform-specific interaction of normal tau with AD hyperphosphorylated

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