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Merck
CN

T8451

Sigma-Aldrich

MonoclonalAnti-Tau, First N-terminal Insert 小鼠抗

clone DC 39N1, purified immunoglobulin, buffered aqueous solution

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MDL编号:
UNSPSC代码:
12352203
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生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

DC 39N1, monoclonal

表单

buffered aqueous solution

分子量

antigen 45-68 kDa

种属反应性

human

技术

immunohistochemistry: 1:1,000
indirect ELISA: 1:2,000
western blot: 1:2,000

同位素/亚型

IgG1

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... MAPT(4137)

免疫原

first tau insert (N1).

外形

Solution in serum-free DMEM (without sodium pyruvate and sodium bicarbonate) containing 0.1% thimerosal as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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象形图

Health hazard

警示用语:

Warning

危险声明

预防措施声明

危险分类

STOT RE 2

靶器官

Kidney

储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Novel Anti-tau Monoclonal antibody With Specificity for NI Terminal Insert.
Mikulova K, et al.,
Neurobiology of Aging, 25, S432-S434 (2004)
Giuseppina Amadoro et al.
Journal of Alzheimer's disease : JAD, 21(2), 445-470 (2010-06-24)
Synapses are ultrastructural sites for memory storage in brain, and synaptic damage is the best pathologic correlate of cognitive decline in Alzheimer's disease (AD). Post-translational hyperphosphorylation, enzyme-mediated truncation, conformational modifications, and aggregation of tau protein into neurofibrillary tangles (NFTs) are
Veronica Corsetti et al.
Brain communications, 2(1), fcaa039-fcaa039 (2020-09-22)
Clinical and neuropathological studies have shown that tau pathology better correlates with the severity of dementia than amyloid plaque burden, making tau an attractive target for the cure of Alzheimer's disease. We have explored whether passive immunization with the 12A12
Valentina Latina et al.
Acta neuropathologica communications, 9(1), 38-38 (2021-03-23)
Retina and optic nerve are sites of extra-cerebral manifestations of Alzheimer's Disease (AD). Amyloid-β (Aβ) plaques and neurofibrillary tangles of hyperphosphorylated tau protein are detected in eyes from AD patients and transgenic animals in correlation with inflammation, reduction of synapses

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