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Merck
CN

T8753

2-(p-Toluidino)-6-naphthalenesulfonic acid potassium salt

suitable for fluorescence, BioReagent

别名:

TNS

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关于此项目

线性分子式:
C17H14NO3SK
化学文摘社编号:
分子量:
351.46
UNSPSC Code:
12352200
PubChem Substance ID:
EC Number:
251-196-1
MDL number:
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SMILES string

[K+].Cc1ccc(Nc2ccc3cc(ccc3c2)S([O-])(=O)=O)cc1

product line

BioReagent

suitability

suitable for fluorescence

storage temp.

2-8°C

Application

Fluorescent probe for the conformational state of proteins.

pictograms

Exclamation mark

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

法规信息

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历史批次信息供参考:

分析证书(COA)

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S Shankara Narayanan et al.
Langmuir : the ACS journal of surfaces and colloids, 23(12), 6712-6718 (2007-05-04)
In this contribution, we report studies on nonspecific protein-DNA interactions of an enzyme protein bovine pancreatic alpha-chymotrypsin (CHT) with genomic DNA (from salmon testes) using two biologically common fluorescent probes: 1-anilinonaphthalene-8-sulfonate (ANS) and 2,6-p-toluidinonaphthalene sulfonate (TNS). TNS molecules that are
Ilona Fitos et al.
Biochimica et biophysica acta, 1760(11), 1704-1712 (2006-09-30)
Imatinib is a selective tyrosine kinase inhibitor, successfully used for the treatment of chronic myelogenous leukaemia. Its strong plasma protein binding referred to alpha1-acid glycoprotein (AGP) component was found to inhibit the pharmacological activity. AGP shows genetic polymorphism and the
Zhi-Jun Wang et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 70(4), 892-897 (2007-12-07)
The interaction between 2-p-toluidinylnaphthalene-6-sulfonate (TNS) and ciliate Euplotes Octocarinatus centrin (Cen) has been studied by fluorescence spectroscopy. The binding constants of TNS with Cen were measured at different temperature in the 0.01M Hepes, pH 7.4. The binding process is exothermic
Martin Stefl et al.
Analytical biochemistry, 410(1), 62-69 (2010-11-17)
The phasor method of treating fluorescence lifetime data provides a facile and convenient approach to characterize lifetime heterogeneity and to detect the presence of excited state reactions such as solvent relaxation and Förster resonance energy transfer. The method uses a
Guoting Li et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 67(5), 1189-1193 (2006-11-28)
Glu is highly conserved as the first amino acid of E-helix of the EF-hand protein. In this paper, Glu 101, the first amino acid of E-helix of the third EF-hand motif in Euplotes octocarinatus centrin (EoCen) was mutated to be

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