U3128
Uroporphyrin I dihydrochloride
≥95%
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关于此项目
经验公式（希尔记法）:
C40H38N4O16 · 2HCl
化学文摘社编号:
分子量:
903.67
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352300
EC Number:
273-038-0
MDL number:
InChI key
DZLKLVAJOHLPKP-ARSPAUKVSA-N
InChI
1S/C40H38N4O16.2ClH/c45-33(46)5-1-17-21(9-37(53)54)29-14-26-19(3-7-35(49)50)23(11-39(57)58)31(43-26)16-28-20(4-8-36(51)52)24(12-40(59)60)32(44-28)15-27-18(2-6-34(47)48)22(10-38(55)56)30(42-27)13-25(17)41-29;;/h13-16,41,44H,1-12H2,(H,45,46)(H,47,48)(H,49,50)(H,51,52)(H,53,54)(H,55,56)(H,57,58)(H,59,60);2*1H/b25-13-,26-14-,27-15-,28-16-,29-14-,30-13-,31-16-,32-15-;;
SMILES string
Cl.Cl.OC(=O)CCc1c(CC(O)=O)c2cc3[nH]c(cc4nc(cc5[nH]c(cc1n2)c(CC(O)=O)c5CCC(O)=O)c(CC(O)=O)c4CCC(O)=O)c(CC(O)=O)c3CCC(O)=O
assay
≥95%
form
powder
reaction suitability
core: porphyrin, reagent type: catalyst
storage temp.
−20°C
Preparation Note
Enzymatically prepared
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
S G Afonso et al.
Journal of enzyme inhibition, 10(2), 141-146 (1996-01-01)
The effect of uroporphyrin I (UI) on several cytosolic and mitochondrial enzymes (succinyl CoA synthetase, delta-aminolevulinic acid synthetase, rhodanese, lactate dehydrogenase) has been examined. All the enzymes were inactivated in the presence of the porphyrin both in the dark and
S G Afonso et al.
Journal of enzyme inhibition, 5(3), 225-233 (1991-01-01)
The action of uroporphyrin I (URO I) on the activity of red cell uroporphyrinogen decarboxylase (URO-D) in the dark and under UV light was studied. Light-dependent-and light-independent inactivation was observed. Both effects increased at increasing concentrations of URO I, the
S Afonso et al.
The international journal of biochemistry & cell biology, 30(4), 535-543 (1998-07-24)
Uroporphyrin and protoporphyrin produce alterations on 5-aminolevulinic acid dehydratase and porphobilinogen deaminase, as a result of a direct effect of porphyrins on the protein structure. With the aim of assessing the possible protection from the porphyrins effect on the proteins
Simon Y L Ching et al.
Analytical biochemistry, 353(2), 257-265 (2006-03-28)
Few methods for assessing total antioxidant capacity (TAC) include both the percentage of inhibition and the length of inhibition in the measurement. Available methods require above ambient constant temperature incubation, reaction preheating, and/or separate assays for testing hydrophilic and hydrophobic
Remarks on the acute intermittent porphyria.
Albrecht Pfäfflin
Annals of clinical biochemistry, 46(Pt 4), 347-348 (2009-07-01)
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