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Merck
CN

U3133

Sigma-Aldrich

UDP-Glucuronosyltransferase 2B4 Microsomes

from human, recombinant, expressed in baculovirus infected insect cells

别名:

UGT2B4

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EC 号:
MDL编号:
UNSPSC代码:
12352204
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生物来源

human

重组

expressed in baculovirus infected insect cells

包装

vial of ~2.5 mg

UniProt登记号

运输

dry ice

储存温度

−70°C

基因信息

human ... UGT2B4(7363)

生化/生理作用

The UDP-Glucuronosyltransferases (UGT) comprise a family of enzymes that detoxify and enhance the urinary excretion of a wide variety of xenobiotic and endogenous substrates by transferring glucuronic acid to sulfhydryl, hydroxyl, aromatic amino, or carboxylic acid groups.

储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Cyril Bigo et al.
Drug metabolism reviews, 45(1), 34-47 (2013-01-22)
The recent progresses in molecular biology and pharmacology approaches allowed the characterization of a series of nuclear receptors (NRs) as efficient regulators of uridine diphosphate glucuronosyltransferase (UGT) genes activity. These regulatory processes ensure an optimized UGT expression in response to
Cong Liu et al.
Fitoterapia, 83(8), 1415-1419 (2013-01-23)
Deoxyschizandrin and schisantherin A are major bioactive lignans isolated from Fructusschisandrae which has been widely used as a tonic in traditional Chinese medicine for manyyears. Inhibition of UDP-glucuronosyltransferases (UGTs) by herbal components might be animportant reason for clinical herb–drug interaction.
Hye Young Ji et al.
Archives of pharmacal research, 36(1), 1-5 (2013-02-02)
DA-9801, the mixture extract of Dioscoreae rhizoma and Dioscorea nipponica Makino, is a new herbal drug currently being evaluated in a phase II clinical study for the treatment of diabetic peripheral neuropathy in Korea. The inhibitory potentials of DA-9801, D.
[Meulengracht disease].
Jonas Zeitz et al.
Praxis, 102(3), 129-135 (2013-02-07)
UGT2B17 as a disease accelerator in CLL.
Yiming Zhong et al.
Blood, 121(7), 1067-1068 (2013-02-16)

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