U5760
(4R)-2-Undecyl-4-thiazolidinecarboxylic acid
≥98% (HPLC)
别名:
2-Undecylthiazolidine-4(R)-carboxylic acid
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关于此项目
经验公式（希尔记法）:
C15H29NO2S
化学文摘社编号:
分子量:
287.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352211
MDL number:
assay
≥98% (HPLC)
form
powder
color
white to off-white
solubility
DMSO: >5 mg/mL
storage temp.
2-8°C
SMILES string
CCCCCCCCCCCC1N[C@@H](CS1)C(O)=O
InChI
1S/C15H29NO2S/c1-2-3-4-5-6-7-8-9-10-11-14-16-13(12-19-14)15(17)18/h13-14,16H,2-12H2,1H3,(H,17,18)/t13-,14?/m0/s1
InChI key
FNBSOIBCKUUVJJ-LSLKUGRBSA-N
Biochem/physiol Actions
BML-241 is a S1P3 (shingosine-1-phosphate receptor) specific antagonist. Treatment with 10 uM BML-241 results in a 40% inhibition of Ca influx in HeLa cells.
BML-241 is a S1P3 receptor antagonist.
Features and Benefits
This compound is featured on the Lysophospholipid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
Preparation Note
(4R)-2-Undecyl-4-thiazolidinecarboxylic acid is soluble in DMSO at a concentration that is >5 mg/ml.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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Bruno Jaime Santacreu et al.
Biochimica et biophysica acta. Molecular and cell biology of lipids, 1866(4), 158888-158888 (2021-01-18)
Collecting duct cells are physiologically subject to the hypertonic environment of the kidney. This condition is necessary for kidney maturation and function but represents a stress condition that requires active strategies to ensure epithelial integrity. Madin-Darby Canine Kidney (MDCK) cells