重组
expressed in E. coli
方案
≥95% (SDS-PAGE)
表单
liquid
分子量
47 kDa
运输
dry ice
储存温度
−70°C
基因信息
human ... UBE2D1(7321), UBE2N(7334)
一般描述
Manufactured for Sigma by Boston Biochem., Inc.
生化/生理作用
Human homologs of the yeast UBC4/5 family and play many important regulatory roles in inflammation and cancer.
Mediates the degradation of a myriad of short-lived regulatory proteins including the tumor suppressor p53 in the presence of E6/E6-AP or MDM2, the c-Fos transcription factor, and the signal-induced ubiquitination of IκBα, UBC5 is an essential gene in yeast.
外形
Solution in 50 mM HEPES, pH 8.0, 100 mM NaCl, 1 mM DTT in 10% glycerol.
储存分类代码
12 - Non Combustible Liquids
法规信息
新产品
此项目有
The ubiquitin-proteasome proteolytic pathway.
A Ciechanover
Cell, 79(1), 13-21 (1994-10-07)
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