表单
solid
颜色
white to off-white
mp
94-95 °C
储存温度
2-8°C
SMILES字符串
OC(=O)\C=C/C(O)=O.C[N+](C)([O-])CCCOc1nn(Cc2ccccc2)c3ccccc13
InChI
1S/C19H23N3O2.C4H4O4/c1-22(2,23)13-8-14-24-19-17-11-6-7-12-18(17)21(20-19)15-16-9-4-3-5-10-16;5-3(6)1-2-4(7)8/h3-7,9-12H,8,13-15H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
QFAFNBZWRXPMSY-BTJKTKAUSA-N
应用
Benzydamine N-oxide hydrogen maleate can be used for spectroscopic analyses.
生化/生理作用
CYP2C9 substrate
包装
Bottomless glass bottle. Contents are inside inserted fused cone.
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?
A E Rettie et al.
Pharmacogenetics, 10(3), 275-277 (2000-05-10)
A Santi et al.
Xenobiotica; the fate of foreign compounds in biological systems, 32(1), 73-86 (2002-02-01)
1. Benzydamine (BZ), a non-steroidal anti-inflammatory drug used in human and veterinary medicine, is not licensed for use in food-producing species. Biotransformation of BZ in cattle has not been reported previously and is investigated here using liver microsomes and precision-cut
B Catanese et al.
Pharmacological research communications, 18(4), 385-403 (1986-04-01)
A method for the extraction and quantification of benzydamine and its metabolite N-oxide by liquid chromatography with fluorescence detection in plasma samples is described. This method has adequate sensitivity, specificity and is reproducible. The use of the extraction column allowed
G A Baldock et al.
Journal of chromatography, 529(1), 113-123 (1990-07-13)
A simple, sensitive and selective method for the determination of benzydamine in human plasma and urine, and for benzydamine N-oxide in urine, has been developed using high-performance liquid chromatography in the reversed-phase mode. The limit of reliable determination of benzydamine
A Kawaji et al.
Biochimica et biophysica acta, 1425(1), 41-46 (1998-11-14)
Benzydamine (BZY) N-oxidation mediated by flavin-containing monooxygenase (FMO) was evaluated in perfused brain and liver. Following 20 min of perfusion with modified Ringer solution, the infusion of BZY into brain or liver led to production of BZY N-oxide. BZY N-oxide
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