InChI
1S/C19H23N3O2.C4H4O4/c1-22(2,23)13-8-14-24-19-17-11-6-7-12-18(17)21(20-19)15-16-9-4-3-5-10-16;5-3(6)1-2-4(7)8/h3-7,9-12H,8,13-15H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
InChI key
QFAFNBZWRXPMSY-BTJKTKAUSA-N
SMILES string
OC(=O)\C=C/C(O)=O.C[N+](C)([O-])CCCOc1nn(Cc2ccccc2)c3ccccc13
form
solid
color
white to off-white
mp
94-95 °C
storage temp.
2-8°C
Application
Benzydamine N-oxide hydrogen maleate can be used for spectroscopic analyses.
Biochem/physiol Actions
CYP2C9 substrate
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
A Santi et al.
Xenobiotica; the fate of foreign compounds in biological systems, 32(1), 73-86 (2002-02-01)
1. Benzydamine (BZ), a non-steroidal anti-inflammatory drug used in human and veterinary medicine, is not licensed for use in food-producing species. Biotransformation of BZ in cattle has not been reported previously and is investigated here using liver microsomes and precision-cut
B Catanese et al.
Pharmacological research communications, 18(4), 385-403 (1986-04-01)
A method for the extraction and quantification of benzydamine and its metabolite N-oxide by liquid chromatography with fluorescence detection in plasma samples is described. This method has adequate sensitivity, specificity and is reproducible. The use of the extraction column allowed
Can caffeine metabolism be used as an in-vivo probe for human flavin-containing monooxygenase activity?
A E Rettie et al.
Pharmacogenetics, 10(3), 275-277 (2000-05-10)
G A Baldock et al.
Journal of chromatography, 529(1), 113-123 (1990-07-13)
A simple, sensitive and selective method for the determination of benzydamine in human plasma and urine, and for benzydamine N-oxide in urine, has been developed using high-performance liquid chromatography in the reversed-phase mode. The limit of reliable determination of benzydamine
A Kawaji et al.
Biochimica et biophysica acta, 1425(1), 41-46 (1998-11-14)
Benzydamine (BZY) N-oxidation mediated by flavin-containing monooxygenase (FMO) was evaluated in perfused brain and liver. Following 20 min of perfusion with modified Ringer solution, the infusion of BZY into brain or liver led to production of BZY N-oxide. BZY N-oxide
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持