UC456
盐酸曲马多
≥98% (HPLC), solid
别名:
(±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
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关于此项目
经验公式（希尔记法）:
C16H25NO2 · HCl
化学文摘社编号:
分子量:
299.84
UNSPSC Code:
12161501
PubChem Substance ID:
EC Number:
252-950-2
MDL number:
assay
≥98% (HPLC)
form
solid
drug control
USDEA Schedule IV
color
white to off-white
mp
178-181 °C
solubility
H2O: soluble
storage temp.
2-8°C
SMILES string
Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
InChI
1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
InChI key
PPKXEPBICJTCRU-XMZRARIVSA-N
Application
Tramadol hydrochloride has been used for pharmacokinetic studies after its oral administration in female goats.
Biochem/physiol Actions
Opioid analgesic; P450 substrate.
Features and Benefits
This compound was developed by Shionogi. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
Tramadol hydrochloride is soluble in water.
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signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
A B de Sousa et al.
Journal of veterinary pharmacology and therapeutics, 31(1), 45-51 (2008-01-08)
The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of these substances following intravenous (i.v.) and oral
Arshi Kizilbash et al.
Journal of pain research, 7, 149-161 (2014-04-09)
Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain
Jennifer L Boonstra et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 46(3), 476-481 (2015-09-10)
Tramadol is a synthetic, centrally acting, opiate-like analgesic that is structurally related to codeine and morphine. The objective of this study was to determine the pharmacokinetics of tramadol hydrochloride and its major active metabolite O-desmethyltramadol (M1) in the California sea