UC456
盐酸曲马多
≥98% (HPLC), solid
别名:
(±)-cis-2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol hydrochloride
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关于此项目
经验公式（希尔记法）:
C16H25NO2 · HCl
化学文摘社编号:
分子量:
299.84
UNSPSC Code:
12161501
PubChem Substance ID:
EC Number:
252-950-2
MDL number:
InChI key
PPKXEPBICJTCRU-XMZRARIVSA-N
InChI
1S/C16H25NO2.ClH/c1-17(2)12-14-7-4-5-10-16(14,18)13-8-6-9-15(11-13)19-3;/h6,8-9,11,14,18H,4-5,7,10,12H2,1-3H3;1H/t14-,16+;/m1./s1
SMILES string
Cl.COc1cccc(c1)[C@@]2(O)CCCC[C@@H]2CN(C)C
assay
≥98% (HPLC)
form
solid
drug control
USDEA Schedule IV
color
white to off-white
mp
178-181 °C
solubility
H2O: soluble
storage temp.
2-8°C
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Application
Tramadol hydrochloride has been used for pharmacokinetic studies after its oral administration in female goats.
Biochem/physiol Actions
Opioid analgesic; P450 substrate.
Features and Benefits
This compound was developed by Shionogi. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Preparation Note
Tramadol hydrochloride is soluble in water.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Chronic 2 - STOT SE 3
target_organs
Central nervous system
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
法规信息
新产品
此项目有
A B de Sousa et al.
Journal of veterinary pharmacology and therapeutics, 31(1), 45-51 (2008-01-08)
The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of these substances following intravenous (i.v.) and oral
Arshi Kizilbash et al.
Journal of pain research, 7, 149-161 (2014-04-09)
Patients with chronic non-malignant pain report impairments of physical, social, and psychological well-being. The goal of pain management should include reducing pain and improving quality of life. Patients with chronic pain require medications that are able to provide adequate pain
Jennifer L Boonstra et al.
Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 46(3), 476-481 (2015-09-10)
Tramadol is a synthetic, centrally acting, opiate-like analgesic that is structurally related to codeine and morphine. The objective of this study was to determine the pharmacokinetics of tramadol hydrochloride and its major active metabolite O-desmethyltramadol (M1) in the California sea
Emrah Yuruk et al.
Journal of endourology, 29(4), 463-467 (2014-10-01)
To compare the outcomes of these minimally invasive procedures in this patient population. The database of our institution has been retrospectively reviewed, and medical records of urolithiasis patients with a solitary kidney who underwent flexible ureteroscopy (F-URS) or extracorporeal shock
Hiroyuki Sekiguchi et al.
Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 20(4), 617-623 (2015-04-26)
Nonsteroidal anti-inflammatory drugs (NSAIDs) are often used to treat inflammation, pain, and fever, but no criterion standard exists for the management of postoperative pain following spinal surgery. In the present study, we compared the analgesic efficacy of loxoprofen sodium (loxoprofen)
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