V119
Verruculogen
powder
别名:
1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[1m]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, TR 1
表单
powder
技术
HPLC: suitable
gas chromatography (GC): suitable
颜色
white
溶解性
chloroform: 20 mg/mL
包装形式
neat
储存温度
−20°C
SMILES字符串
COc1ccc2c3[C@H](O)[C@]4(O)N([C@H]5CC(C)(C)OO[C@H](\C=C(\C)C)n(c35)c2c1)C(=O)[C@@H]6CCCN6C4=O
InChI
1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1
InChI key
LRXYHMMJJCTUMY-GWXUGYLUSA-N
应用
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
生化/生理作用
Selective blocker of high conductance Ca2+-activated (Maxi-K) potassium channels.
免责声明
Photosensitive
法规信息
新产品
此项目有
M I Selala et al.
Journal of natural products, 54(1), 207-212 (1991-01-01)
Paxilline was isolated from Penicillium paxilli (NRRL 6110). It was studied together with penitrem B and verruculogen in the electrically stimulated guinea pig ileum. All three mycotoxins enhanced the electrically induced twitch contractions, without influencing the contractions provoked by exogenous
H G Knaus et al.
Biochemistry, 33(19), 5819-5828 (1994-05-17)
Tremorgenic indole alkaloids produce neurological disorders (e.g., staggers syndromes) in ruminants. The mode of action of these fungal mycotoxins is not understood but may be related to their known effects on neurotransmitter release. To determine whether these effects could be
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