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Merck
CN

V119

Supelco

Verruculogen

powder

别名:

1,10,10a,14,14a,15b-Hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5a,11a,15a-triazacyclooct[1m]indeno[5,6-b]fluorene-11,15(2H,13H)-dione, TR 1

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关于此项目

MDL编号:
UNSPSC代码:
41116107
PubChem化学物质编号:
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表单

powder

技术

HPLC: suitable
gas chromatography (GC): suitable

颜色

white

溶解性

chloroform: 20 mg/mL

包装形式

neat

储存温度

−20°C

SMILES字符串

COc1ccc2c3[C@H](O)[C@]4(O)N([C@H]5CC(C)(C)OO[C@H](\C=C(\C)C)n(c35)c2c1)C(=O)[C@@H]6CCCN6C4=O

InChI

1S/C27H33N3O7/c1-14(2)11-20-29-18-12-15(35-5)8-9-16(18)21-22(29)19(13-26(3,4)37-36-20)30-24(32)17-7-6-10-28(17)25(33)27(30,34)23(21)31/h8-9,11-12,17,19-20,23,31,34H,6-7,10,13H2,1-5H3/t17-,19-,20+,23-,27+/m0/s1

InChI key

LRXYHMMJJCTUMY-GWXUGYLUSA-N

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

生化/生理作用

Selective blocker of high conductance Ca2+-activated (Maxi-K) potassium channels.

免责声明

Photosensitive

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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M I Selala et al.
Journal of natural products, 54(1), 207-212 (1991-01-01)
Paxilline was isolated from Penicillium paxilli (NRRL 6110). It was studied together with penitrem B and verruculogen in the electrically stimulated guinea pig ileum. All three mycotoxins enhanced the electrically induced twitch contractions, without influencing the contractions provoked by exogenous
H G Knaus et al.
Biochemistry, 33(19), 5819-5828 (1994-05-17)
Tremorgenic indole alkaloids produce neurological disorders (e.g., staggers syndromes) in ruminants. The mode of action of these fungal mycotoxins is not understood but may be related to their known effects on neurotransmitter release. To determine whether these effects could be

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