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Merck
CN

V1258

[Arg8]-Vasotocin-Gly-Lys-Arg

≥97% (HPLC)

别名:

Hydrin I

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关于此项目

经验公式（希尔记法）:
C57H93N21O16S2
化学文摘社编号:
122842-47-1
分子量:
1392.61
PubChem Substance ID:
24900714
UNSPSC Code:
12352200
MDL number:
MFCD00076729

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产品名称

[Arg8]-Vasotocin-Gly-Lys-Arg, ≥97% (HPLC)

InChI

1S/C57H93N21O16S2/c1-3-29(2)45-53(91)72-35(17-18-41(60)80)49(87)75-38(24-42(61)81)50(88)76-39(28-96-95-27-32(59)46(84)74-37(51(89)77-45)23-30-13-15-31(79)16-14-30)54(92)78-22-8-12-40(78)52(90)71-33(10-6-20-66-56(62)63)47(85)69-25-43(82)68-26-44(83)70-34(9-4-5-19-58)48(86)73-36(55(93)94)11-7-21-67-57(64)65/h13-16,29,32-40,45,79H,3-12,17-28,58-59H2,1-2H3,(H2,60,80)(H2,61,81)(H,68,82)(H,69,85)(H,70,83)(H,71,90)(H,72,91)(H,73,86)(H,74,84)(H,75,87)(H,76,88)(H,77,89)(H,93,94)(H4,62,63,66)(H4,64,65,67)

SMILES string

CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)C(N)CSSCC(NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O)C(=O)N3CCCC3C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NCC(=O)NC(CCCCN)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI key

BJRAYGWQMPNTHC-UHFFFAOYSA-N

assay

≥97% (HPLC)

UniProt accession no.

P01185

storage temp.

−20°C

Gene Information

human ... AVP(551)

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
014H08931

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R Acher et al.
Biology of the cell, 89(5-6), 283-291 (1997-08-01)
Volemia and osmolality homeostasis is ensured in vertebrates through neuroendocrine reflexes, involving an afferent neural branch from baro- and osmo-receptors to hypothalamus and an efferent endocrine branch from secretory neurons to target hydroosmotic cells equipped with receptors and effectors. Whereas
Y Rouille et al.
Neuropeptides, 29(5), 301-307 (1995-11-01)
The biological properties of vasotocin, hydrin 1 (vasotocinyl-Gly-Lys-Arg) and hydrin 2 (vasotocinyl-Gly), in particular the hydro-osmotic activities on the frog skin, the frog urinary bladder and the frog kidney, have been compared. Hydrins are as active or more active than
J T Winslow et al.
European journal of pharmacology, 233(1), 101-107 (1993-03-16)
The neurohypophyseal peptide hormone arginine-vasopressin functions as a neuropeptide in several brain areas in addition to its role as a posterior pituitary hormone. Several studies indicate that arginine-vasopressin and arginine-vasopressin receptors appear early in the infant rat brain. To determine
P Eggena et al.
The American journal of physiology, 259(4 Pt 1), E524-E528 (1990-10-01)
Hydrin 1 is the biosynthetic precursor of vasotocin in Xenopus laevis. We have synthesized deamino and fluorescein analogues of hydrin 1 and characterized their physiological action in the urinary bladder of the toad, Bufo marinus. 1-Deamino-hydrin 1 (d-hydrin) was more
Satomi Kohno et al.
General and comparative endocrinology, 132(3), 485-498 (2003-07-10)
In most amphibians, [Arg(8)] vasotocin (VT) has an antidiuretic effect that is coupled to the activation of adenylate cyclase. In contrast, mesotocin (MT) has a diuretic effect and acts via the inositol phosphate/calcium signaling pathway in amphibians. To further clarify
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