V1260
VEGF Receptor-3 (Flt-4)/Fc Chimera human
>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
别名:
Vascular Endothelial Growth Factor Receptor‑3
生物来源
human
重组
expressed in NSO cells
方案
>95% (SDS-PAGE)
表单
lyophilized powder
分子量
calculated mol wt ~112 kDa
包装
pkg of 50 μg
储存条件
avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
杂质
endotoxin, tested
UniProt登记号
储存温度
−20°C
基因信息
human ... FLT4(2324)
应用
VEGF Receptor-3 (Flt-4)/Fc chimera human is a disulfide-linked homodimeric protein that consists of VEGF Receptor-3 fused with6X histidine tagged Fc portion of human IgG1 by a polypeptide linker. It may be used as a specific marker for lymphatic vessels as well as plays a pivotal role in the development of the lymphatic vessel system.
生化/生理作用
VEGF Receptor-3 (Flt-4) belongs to class III subfamily of RTKs and is expressed mainly in endothelial cells. VEGF Receptor-3 blocks VEGF-C/D and hence inhibits lymphangiogenesis and lymphatic metastasis in orthotopic urinary bladder cancer (OUBC).
外形
Lyophilized from a 2 μm filtered solution in phosphate buffered saline.
分析说明
The binding affinity of recombinant VEGF R3 has not been determined. Its intended use is for western blot and ELISA standards.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
Soluble vascular endothelial growth factor receptor-3 suppresses lymphangiogenesis and lymphatic metastasis in bladder cancer.
Molecular Cancer, 10 (2011)
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