V2390

VRT-532

Name: VRT-532
Brand: SIGMA

≥98% (HPLC)

别名:

4-Methyl-2-(5-phenyl-1H-pyrazol-3-yl)phenol, CFpot 532

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关于此项目

经验公式（希尔记法）:

C₁₆H₁₄N₂O

化学文摘社编号:

38214-71-0

分子量:

250.30

UNSPSC代码:

12352200

主要文件

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方案

≥98% (HPLC)

表单

solid

溶解性

DMSO: >20 mg/mL

储存温度

−20°C

InChI

1S/C16H14N2O/c1-11-7-8-16(19)13(9-11)15-10-14(17-18-15)12-5-3-2-4-6-12/h2-10,19H,1H3,(H,17,18)

InChI key

AQWKVJFRGORALM-UHFFFAOYSA-N

生化/生理作用

VRT-532 is a mutated G551D CFTR corrector.

VRT-532 is a mutated G551D CFTR corrector. VRT-532 mediates G551D-CFTR by enhancement of ATP affinity of the mutant. VRT-532 also potentiates F508del mutated CFTR and works specifically on mutant CFTR rather than other membrane proteins.

特点和优势

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.