V3265
VU0029767
≥98% (HPLC)
别名:
(E)-2-(4-Ethoxyphenylamino)-N′-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide
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关于此项目
经验公式（希尔记法）:
C21H21N3O3
化学文摘社编号:
分子量:
363.41
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
InChI
1S/C21H21N3O3/c1-2-27-17-10-8-16(9-11-17)22-14-21(26)24-23-13-19-18-6-4-3-5-15(18)7-12-20(19)25/h3-13,22,25H,2,14H2,1H3,(H,24,26)/b23-13+
SMILES string
CCOc1ccc(NCC(=O)N\N=C\c2c(O)ccc3ccccc23)cc1
InChI key
JWRJGCUSLSJMMD-YDZHTSKRSA-N
assay
≥98% (HPLC)
form
powder
color
gray-brown
solubility
DMSO: >10 mg/mL
storage temp.
room temp
Biochem/physiol Actions
VU0029767 is a selective, positive allosteric modulator at the muscarinic M1 acetylcholine receptor. It shifts concentration-dependent response to acetylcholine at least five-fold, but does not compete at the ACh binding site. VU0029767 also potentiates the effects of allosteric agonist TBPB.
VU0029767 is a selective, positive allosteric modulator at the muscarinic M1 acetylcholine receptor. VU0029767 also potentiates the effects of allosteric agonist TBPB.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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