InChI
1S/C24H32N4O7.2ClH.H2O/c29-27(30)23-5-1-21(2-6-23)19-25-9-13-33-14-10-26(12-16-35-18-17-34-15-11-25)20-22-3-7-24(8-4-22)28(31)32;;;/h1-8H,9-20H2;2*1H;1H2
SMILES string
O.Cl.Cl.[O-][N+](=O)c1ccc(CN2CCOCCOCCN(CCOCC2)Cc3ccc(cc3)[N+]([O-])=O)cc1
InChI key
UARRNDBWOZCTNV-UHFFFAOYSA-N
form
solid
storage condition
desiccated
solubility
deionized water: >10 mg/mL
storage temp.
2-8°C
Biochem/physiol Actions
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1 at low micromolar affinity, but it does not inhibit Kir2.1 or Kir4.1. VU590 appears to act by blocking the ion permeation pathway of the channel.
Features and Benefits
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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