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About This Item
经验公式（希尔记法）:
C24H32N4O7·2HCl · xH2O
分子量:
561.46 (anhydrous basis)
MDL编号:
UNSPSC代码:
12352203
PubChem化学物质编号:
表单
solid
储存条件
desiccated
溶解性
deionized water: >10 mg/mL
储存温度
2-8°C
SMILES字符串
O.Cl.Cl.[O-][N+](=O)c1ccc(CN2CCOCCOCCN(CCOCC2)Cc3ccc(cc3)[N+]([O-])=O)cc1
InChI
1S/C24H32N4O7.2ClH.H2O/c29-27(30)23-5-1-21(2-6-23)19-25-9-13-33-14-10-26(12-16-35-18-17-34-15-11-25)20-22-3-7-24(8-4-22)28(31)32;;;/h1-8H,9-20H2;2*1H;1H2
InChI key
UARRNDBWOZCTNV-UHFFFAOYSA-N
生化/生理作用
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1
VU590 inhibits ROMK at sub-micromolar affinity (294 nM) and Kir7.1 at low micromolar affinity, but it does not inhibit Kir2.1 or Kir4.1. VU590 appears to act by blocking the ion permeation pathway of the channel.
特点和优势
This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示用语：
Warning
危险分类
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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