V5387
Anti-Vesicular Acetylcholine Transporter (VAChT) antibody produced in rabbit
affinity isolated antibody, buffered aqueous solution
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
form
buffered aqueous solution
mol wt
antigen ~70 kDa
species reactivity
rat, human
technique(s)
immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using 4% paraformaldehyde perfusion-fixed, floating tissue sections of rat brain, indirect immunofluorescence: 1:500 using NGF-treated PC12 cells, western blot: 1:2,000 using rat brain extract
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... SLC18A3(6572)
rat ... Slc18a3(60422)
Immunogen
synthetic peptide corresponding to the C-terminal of rat vesicular acetylcholine transporter (VAChT) (amino acids 512-530).
Application
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (2 papers)
Immunohistochemistry (2 papers)
Biochem/physiol Actions
The sequence is highly conserved in human VAChT.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.
法规信息
新产品
此项目有
David Moszkowicz et al.
The journal of sexual medicine, 8(4), 1112-1122 (2011-01-29)
Little detailed information is available concerning autonomic and somatic nerve supply to the clitoris, potentially causing difficulties for nerve preservation during pelvic and perineal surgery. To identify the location and type (nitrergic, adrenergic, cholinergic and sensory) of nerve fibers in
Helene Bensoussan et al.
Toxicology, 261(1-2), 59-67 (2009-05-05)
Uranium is a heavy metal naturally present in the environment that may be chronically ingested by the population. Previous studies have shown that uranium is present in the brain and alters behaviour, notably locomotor activity, sensorimotor ability, sleep/wake cycle and
T L Powley et al.
Neuroscience, 186, 188-200 (2011-05-03)
Intramuscular arrays (IMAs), vagal mechanoreceptors that innervate gastrointestinal smooth muscle, have not been completely described structurally or functionally. To delineate more fully the architecture of IMAs and to consider the structure-function implications of the observations, the present experiment examined the
Keith N Darrow et al.
The Journal of comparative neurology, 498(3), 403-414 (2006-07-28)
Immunostaining mouse cochleas for tyrosine hydroxylase (TH) and dopamine beta-hydroxylase suggests that there is a rich adrenergic innervation throughout the auditory nerve trunk and a small dopaminergic innervation of the sensory cell areas. Surgical cuts in the brainstem confirm these
Neuropeptide coding of sympathetic preganglionic neurons; focus on adrenally projecting populations.
N N Kumar et al.
Neuroscience, 170(3), 789-799 (2010-08-03)
Chemical coding of sympathetic preganglionic neurons (SPN) suggests that the chemical content of subpopulations of SPN can define their function. Since neuropeptides, once synthesized are transported to the axon terminal, most demonstrated chemical coding has been identified using immunoreactive terminals
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