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Merck
CN

WH0051156M2

Monoclonal Anti-SERPINA10 antibody produced in mouse

clone 1E11, purified immunoglobulin, buffered aqueous solution

别名:

Anti-PZI, Anti-ZPI, Anti-serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

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关于此项目

NACRES:
NA.41
UNSPSC Code:
12352203
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biological source

mouse

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

1E11, monoclonal

form

buffered aqueous solution

species reactivity

human

technique(s)

immunoprecipitation (IP): suitable, indirect ELISA: suitable, western blot: 1-5 μg/mL

isotype

IgG2aκ

GenBank accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... SERPINA10(51156)

General description

Serpin family A member 10 (SERPIN10) or protein Z-dependent inhibitor is a single-chain glycoprotein which is expressed in the liver. The gene encoding it is localized on human chromosome 14q32.13.

Immunogen

SERPINA10 (AAH22261, 22 a.a. ~ 444 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL

Biochem/physiol Actions

Serpin family A member 10 (SERPIN10) inhibits coagulation factors X and XI. Variations in the gene encoding this protein have been associated with thrombophilia.

Physical form

Solution in phosphate buffered saline, pH 7.4

Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


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存储类别

12 - Non Combustible Liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

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分析证书(COA)

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Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis.
Gorski MM
PLoS ONE, 11(3), e0151347-e0151347 (2016)
Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas
Justyna L, et.al
Modern Pathology, 22, 261-272 (2009)
Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas.
Shiiba M
Oncology Reports, 24(1), 241-249 (2010)