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Merck
CN

WH0051156M2

Sigma-Aldrich

Monoclonal Anti-SERPINA10 antibody produced in mouse

clone 1E11, purified immunoglobulin, buffered aqueous solution

别名:

Anti-PZI, Anti-ZPI, Anti-serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10

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关于此项目

UNSPSC代码:
12352203
NACRES:
NA.41
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生物来源

mouse

偶联物

unconjugated

抗体形式

purified immunoglobulin

抗体产品类型

primary antibodies

克隆

1E11, monoclonal

表单

buffered aqueous solution

种属反应性

human

技术

immunoprecipitation (IP): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL

同位素/亚型

IgG2aκ

GenBank登记号

UniProt登记号

运输

dry ice

储存温度

−20°C

基因信息

human ... SERPINA10(51156)

一般描述

Serpin family A member 10 (SERPIN10) or protein Z-dependent inhibitor is a single-chain glycoprotein which is expressed in the liver. The gene encoding it is localized on human chromosome 14q32.13.

免疫原

SERPINA10 (AAH22261, 22 a.a. ~ 444 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
LAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL

生化/生理作用

Serpin family A member 10 (SERPIN10) inhibits coagulation factors X and XI. Variations in the gene encoding this protein have been associated with thrombophilia.

外形

Solution in phosphate buffered saline, pH 7.4

法律信息

GenBank is a registered trademark of United States Department of Health and Human Services

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储存分类代码

12 - Non Combustible Liquids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Single Nucleotide Variant rs2232710 in the Protein Z-Dependent Protease Inhibitor (ZPI, SERPINA10) Gene Is Not Associated with Deep Vein Thrombosis.
Gorski MM
PLoS ONE, 11(3), e0151347-e0151347 (2016)
Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas
Masashi S, et.al
Oncology Reports, 24(1), 241-249 (2010)
Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas
Justyna L, et.al
Modern Pathology, 22, 261-272 (2009)
Down-regulated expression of SERPIN genes located on chromosome 18q21 in oral squamous cell carcinomas.
Shiiba M
Oncology Reports, 24(1), 241-249 (2010)
Justyna Leja et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 22(2), 261-272 (2008-10-28)
The gene expression profile of metastasizing serotonin-producing neuroendocrine carcinomas, which arise from enterochromaffin cells in the jejunum and ileum, is still largely unknown. The aim of this study was to identify genes and proteins, which are preferentially expressed by neuroendocrine

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