WH0085313M1
Monoclonal Anti-PPIL4 antibody produced in mouse
clone 1C10, purified immunoglobulin, buffered aqueous solution
别名:
Anti-HDCME13P, Anti-peptidylprolyl isomerase (cyclophilin)-like 4
生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
1C10, monoclonal
表单
buffered aqueous solution
种属反应性
human
技术
indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL
同位素/亚型
IgG2aκ
GenBank登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... PPIL4(85313)
一般描述
Peptidylprolyl isomerase like 4 (PPIL4) is part of the cyclophilin family. This family has a role in protein folding, human immunodeficiency virus-1 (HIV-1) infection and immunosuppression by cyclosporin A. The gene encoding PPIL4 is localized on human chromosome 6q24-->q25. It possesses a PPIase motif, a lysine-rich domain, a RNA recognition motif and two bipartite nuclear targeting sequences. PPIL4 is expressed in the kidneys and other tissues.
免疫原
PPIL4 (NP_624311, 395 a.a. ~ 466 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
EKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLY
Sequence
EKEDEDYMPIKNTNQDIYREMGFGHYEEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLY
生化/生理作用
Peptidylprolyl isomerase like 4 (PPIL4) may have a role in the immune system. Polymorphisms in the PPIL4 gene may enhance inflammation during rheumatoid arthritis.
外形
Solution in phosphate buffered saline, pH 7.4
法律信息
GenBank is a registered trademark of United States Department of Health and Human Services
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
历史批次信息供参考:
Molecular cloning, structure and expression of a novel nuclear RNA-binding cyclophilin-like gene (PPIL4) from human fetal brain.
Zeng L
Cytogenetics and Cell Genetics (2001)
Simultaneous genome-wide association studies of anti-cyclic citrullinated peptide in rheumatoid arthritis using penalized orthogonal-components regression
Yanzhu Lin
BMC Proceedings (2009)
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