WH0158158M1
Monoclonal Anti-RASEF antibody produced in mouse
clone 2D5, purified immunoglobulin, buffered aqueous solution
别名:
Anti-FLJ31614, Anti-RAB45, Anti-RAS and EF-hand domain containing
生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
2D5, monoclonal
表单
buffered aqueous solution
种属反应性
human, rat, mouse
技术
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
indirect ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型
IgG2bκ
GenBank登记号
UniProt登记号
运输
dry ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... RASEF(158158)
一般描述
The gene encoding RAS and EF-hand domain containing protein (RASEF) is located on human chromosome 9q21 and is a tumor suppressor gene.
免疫原
RASEF (AAH23566, 631 a.a. ~ 740 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSITNLTGTNSKKSPQMKNCCNG
Sequence
NIREWVDMIEDAAHETVPIMLVGNKADIRDTAATEGQKCVPGHFGEKLAMTYGALFCETSAKDGSNIVEAVLHLAREVKKRTDKDDSRSITNLTGTNSKKSPQMKNCCNG
生化/生理作用
RAS and EF-hand domain containing protein (RASEF) maybe involved in the Ras pathway. It associates with guanine nucleotide tri- and di-phosphates.
外形
Solution in phosphate buffered saline, pH 7.4
法律信息
GenBank is a registered trademark of United States Department of Health and Human Services
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Willem Maat et al.
Investigative ophthalmology & visual science, 49(4), 1291-1298 (2008-04-04)
Recently, a segregation study in families with uveal and cutaneous melanoma identified 9q21 as a potential locus harboring a tumor-suppressor gene (TSG). One of the genes in this area, RASEF, was then analyzed as a candidate TSG, but lack of
Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.
Shintani M
Biochemical and Biophysical Research Communications, 357(3), 661-667 (2007)
Andrew Wang et al.
BMC endocrine disorders, 21(1), 185-185 (2021-09-15)
Cushing's disease (CD) is defined as hypercortisolemia caused by adrenocorticotropic hormone (ACTH)-secreting pituitary adenomas (corticotroph PA) that afflicts humans and dogs. In order to map common aberrant genomic features of CD between humans and dogs, we performed genomic sequencing and
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