Mixed Gender Human LiverPool^™ 20-donor pooled Cryopreserved Hepatocytes

Purpose-pooled hepatocytes provided by BioreclamationIVT are designed for your unique purposes that have the characterization and quality you need for your research. LiverPool^™ hepatocytes are used to conduct toxicity, inhibition and metabolism studies.

See technical bulletins for detailed protocols.

Click here to get a complete list of available hepatocyte lots from BioreclamationIVT.

Once the lot number(s) of interest are determined enter the lot number into the “Certificate of Analysis” request search engine at the bottom of the page to obtain a pdf copy of the CoA. Note, lot number CoA upload is only available on the product number detail page corresponding with the lot number.

The patented LiverPool^™ hepatocytes are blended to ensure sufficient activity levels in all CYP categories. This makes your research more focused and productive. With our large lots sizes and ability to reproduce activity levels, your research results are consistent and repeatable. You benefit from clear data that helps speed discovery and pre-clinical research.

• Purpose-Pooled: A proprietary algorithm, drawing up a cell database of known substrate performances, selects hepatocyte lots from a well-characterized cell bank to achieve targeted enzyme levels*
• Characterization: All LiverPool^™ products are fully characterized across numerous substrates to ensure consistency and reliability
• Format Choice: Available in 5-, 10-, 20- and 50-donor pool sizes
• Savings: In both time and money, LiverPool hepatocytes enable researchers to eliminate pooling procedures, characterization testing and costly multi-donor work
• Large Lot Sizes: All contributory hepatocyte lots are sourced from whole, intact, transplant-quality livers, ensuring each donor lot can create large product sizes. This enables researchers to have great consistency across multiple experiments.
• Quality: All LiverPool lots must meet and exceed stringent quality control specifications prior to release.

* The process for producing the LiverPool^™ pooled human hepatocyte products is covered by one or more U.S. or foreign
patents and patent applications, including U.S. Patent No. 7,604,929.

This product will be shipped in a liquid nitrogen dry shipper supplied from Cryoport. Please remember to ship the container back to Cryoport once you have removed the materials. Additional Cryoport shipping charges may apply.

Please see the Cryoport website for more details on the dry shipper.

Cryopreserved hepatocytes contain a range of metabolizing enzymes which are useful for conducting metabolic pathway identification experiments as stated in the FDA Guidance.*

* Drug Interaction Studies - Study Design, Data Analysis, and Implications for Dosing and Labeling Recommendations (draft):Guidance for Industry, FDA, September 2012.

Liverpool is a trademark of Bioreclamation-IVT Holdings, LLC