生物来源
mouse
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
LG1, monoclonal
表单
buffered aqueous solution
分子量
antigen ~51 kDa
种属反应性
mouse, yeast, human
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
indirect ELISA: suitable
western blot: 20-30 μg/mL using total cell extracts of the A431 human epidermoid carcinoma cell line
同位素/亚型
IgG1
运输
dry ice
储存温度
−20°C
基因信息
human ... ZNF259(8882)
mouse ... Zfp259(22687)
一般描述
ZPR1 is a zinc finger protein that interacts with eEF-1α to modulate cell proliferation. Upon mitogenic stiμLation, cytoplasmic ZPR1 moves to the nucleus and accuμLates in the nucleolus of dividing cells. ZPR1 deficiency causes decreased viability of cells and impaired nucleolar functions . Monoclonal Anti-ZPR1 antibody is specific for human, mouse, and yeast ZPR1.
免疫原
full length human ZPR1.
应用
Monoclonal Anti-ZPR1 antibody is suitable for use in western blot (20-30 μg/mL using total cell extracts of the A431 human epidermoid carcinoma cell line). The product may also be used for immunocytochemistry, indirect ELISA and immunohistochemistry.
外形
0.01M 磷酸缓冲盐溶液，pH 7.4，含 15mM 叠氮化钠。
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
Z Galcheva-Gargova et al.
Molecular biology of the cell, 9(10), 2963-2971 (1998-10-08)
The zinc finger protein ZPR1 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. The function of nuclear ZPR1 has not been defined. Here we demonstrate that ZPR1 accumulates in the nucleolus of proliferating cells. The
L Gangwani et al.
The Journal of cell biology, 143(6), 1471-1484 (1998-12-16)
The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins
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