biological source
mouse
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
LG1, monoclonal
form
buffered aqueous solution
mol wt
antigen ~51 kDa
species reactivity
mouse, yeast, human
technique(s)
immunocytochemistry: suitable, immunohistochemistry: suitable, indirect ELISA: suitable, western blot: 20-30 μg/mL using total cell extracts of the A431 human epidermoid carcinoma cell line
isotype
IgG1
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... ZNF259(8882)
mouse ... Zfp259(22687)
General description
ZPR1 is a zinc finger protein that interacts with eEF-1α to modulate cell proliferation. Upon mitogenic stiμLation, cytoplasmic ZPR1 moves to the nucleus and accuμLates in the nucleolus of dividing cells. ZPR1 deficiency causes decreased viability of cells and impaired nucleolar functions . Monoclonal Anti-ZPR1 antibody is specific for human, mouse, and yeast ZPR1.
Immunogen
full length human ZPR1.
Application
Monoclonal Anti-ZPR1 antibody is suitable for use in western blot (20-30 μg/mL using total cell extracts of the A431 human epidermoid carcinoma cell line). The product may also be used for immunocytochemistry, indirect ELISA and immunohistochemistry.
Physical form
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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存储类别
12 - Non Combustible Liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
法规信息
新产品
此项目有
L Gangwani et al.
The Journal of cell biology, 143(6), 1471-1484 (1998-12-16)
The zinc finger protein ZPR1 is present in the cytoplasm of quiescent mammalian cells and translocates to the nucleus upon treatment with mitogens, including epidermal growth factor (EGF). Homologues of ZPR1 were identified in yeast and mammals. These ZPR1 proteins
Z Galcheva-Gargova et al.
Molecular biology of the cell, 9(10), 2963-2971 (1998-10-08)
The zinc finger protein ZPR1 translocates from the cytoplasm to the nucleus after treatment of cells with mitogens. The function of nuclear ZPR1 has not been defined. Here we demonstrate that ZPR1 accumulates in the nucleolus of proliferating cells. The
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