1.04735
水
tested for PFAS Methods LiChrosolv®
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线性分子式:
H2O
化学文摘社编号:
分子量:
18.02
UNSPSC Code:
41104213
Beilstein/REAXYS Number:
2050024
MDL number:
NACRES:
NA.07
Assay:
≥99.9% (GC)
Bp:
100 °C (lit.)
General description
Per- and polyfluorinated alkyl substances (PFAS) represent a class of synthetic compounds that have gained significant attention due to their widespread use and environmental persistence. Known for their toxicity, PFAS pose serious challenges to both public health and the environment, making effective testing essential. The United States Environmental Protection Agency (US EPA) has established several guidelines for PFAS testing regulations, emphasizing the need for rigorous analytical methods.
Testing for PFAS requires solvents, such as water, acetonitrile, and methanol of exceptionally high purity, which are utilized in both analytical and preparative stages of the analysis. The high sensitivity of liquid chromatography-mass spectrometry (LC-MS) instruments, combined with the need for trace-level detection of PFAS, necessitates the use of solvents that are free from PFAS contamination. Any presence of PFAS in these solvents can lead to misleading results, resulting in false positives or an overestimation of PFAS levels, ultimately compromising the validity of analytical results and conclusions. Therefore, ensuring solvent purity is paramount for accurate and reliable PFAS analysis.
LiChrosolv® solvents, tested for PFAS methods, are engineered to meet the demands of this critical application. Each batch undergoes rigorous testing against all analytes outlined in EPA methods EPA 533, EPA 537.1, and EPA 1633. These solvents are designed to minimize background interference and contain no PFAS compounds above the limit values defined by each EPA method. This ensures reliable and effective testing, facilitating the identification and quantitation of PFAS analytes while eliminating the risk of false positive or negative results in LC-MS/MS analysis.
Testing for PFAS requires solvents, such as water, acetonitrile, and methanol of exceptionally high purity, which are utilized in both analytical and preparative stages of the analysis. The high sensitivity of liquid chromatography-mass spectrometry (LC-MS) instruments, combined with the need for trace-level detection of PFAS, necessitates the use of solvents that are free from PFAS contamination. Any presence of PFAS in these solvents can lead to misleading results, resulting in false positives or an overestimation of PFAS levels, ultimately compromising the validity of analytical results and conclusions. Therefore, ensuring solvent purity is paramount for accurate and reliable PFAS analysis.
LiChrosolv® solvents, tested for PFAS methods, are engineered to meet the demands of this critical application. Each batch undergoes rigorous testing against all analytes outlined in EPA methods EPA 533, EPA 537.1, and EPA 1633. These solvents are designed to minimize background interference and contain no PFAS compounds above the limit values defined by each EPA method. This ensures reliable and effective testing, facilitating the identification and quantitation of PFAS analytes while eliminating the risk of false positive or negative results in LC-MS/MS analysis.
Application
LiChrosolv® PFAS-tested solvents are suitable for testing PFAS in drinking water according to EPA methods 533 and 537.1. These solvents can also be used for testing PFAS in other aqueous matrices including wastewater, surface water, groundwater, and landfill leachate, as well as for soil, sediment, biosolids, and fish and shellfish following the EPA method 1633.
PFAS Testing Features:
PFAS Testing Features:
- QC Batch Tested: 40 PFAS analytes tested according to EPA 533 (25 analytes), EPA 537.1 (18 analytes), and EPA 1633 (40 analytes).
- Lot to Lot Consistency: Multiple batches validated by a third-party accredited testing laboratory and internal laboratories.
Features and Benefits
- Application Security: Quality control on 40 PFAS analytes according to EPA 533, EPA 537.1, and EPA 1633.
- Time and Cost Savings: EPA 1633 requires batch validation unless the vendor tests for PFAS analytes listed in this method.
- Lowest Impurity Profile: Ensures an interference-free baseline.
- LC-MS Suitability: ESI/APCI (+) < 2 ppb; ESI/APCI (-) < 10 ppb.
- Minimized Contamination: Borosilicate glass bottles reduce contamination with metal ions.
- Trace Metal Impurity Control: Levels of trace metal impurities are minimized to <5 ppb, reducing metal ion adduct formation.
- Microfiltration: Solvents are filtered through a 0.2 μm filter to ensure purity.
Legal Information
LICHROSOLV is a registered trademark of Merck KGaA, Darmstadt, Germany
存储类别
12 - Non Combustible Liquids
wgk
nwg
flash_point_f
Not applicable
flash_point_c
Not applicable
商品
LC-MS method separates 32 PFAS compounds in drinking water following EPA methods 533, 537, and 537.1. EPA 8327.
Learn how method EPA 533 is used for sample collection and preparation, featuring Supelclean™ ENVI-WAX™ SPE cartridges for LC-MS analysis on an Ascentis® Express PFAS HPLC Column.
LC-MS/MS determination of per- and polyfluoroalkyl substances (PFAS) in water samples using Supelclean™ ENVI-WAX™ SPE cartridges as per EPA Method 1633.
Liquid Chromatography–Mass Spectrometry (LC-MS) separation of 33 PFAS (Per- and poly-fluoroalkyl substances) using a superficially porous silica particles (SPP) based Ascentis® Express C18 column.
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