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Merck
CN

33097-U

三甲基苯基氢氧化铵

0.2 M in methanol

别名:

三甲基苯基氢氧化铵 溶液, 苯基三甲基氢氧化铵

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关于此项目

线性分子式:
(CH3)3N(OH)C6H5
化学文摘社编号:
分子量:
153.22
PubChem Substance ID:
UNSPSC Code:
12352200
Beilstein/REAXYS Number:
3917033
MDL number:
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grade

derivatization grade ((GC derivatization))

reaction suitability

reagent type: derivatization reagent
reaction type: Esterifications

packaging

pkg of 1 × 10 mL (33097-U)

concentration

0.2 M in methanol

SMILES string

[OH-].C[N+](C)(C)c1ccccc1

InChI

1S/C9H14N.H2O/c1-10(2,3)9-7-5-4-6-8-9;/h4-8H,1-3H3;1H2/q+1;/p-1

InChI key

HADKRTWCOYPCPH-UHFFFAOYSA-M

General description

Trimethylanilinium hydroxide (TMAH) is an alkylating agent, which is effectively used esterification of carboxylic acids, etherfication of alcohols and N-alkylation of amino groups.

Application

It is used to derivatize the serum sample for determination of Topiramate in Epileptic patients using GC-MS analysis.

Other Notes

Reagent for carboxylic acid methyl ester, methyl esters.


signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 1

target_organs

Eyes

存储类别

3 - Flammable liquids

wgk

WGK 3

flash_point_f

51.8 °F - closed cup

flash_point_c

11 °C - closed cup

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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E.W. Robb and J.J. Westbrook III
Analytical Chemistry, 35, 1644-1644 (1963)
Vladimir Zaikin, John M. Halket
A Handbook of Derivatives for Mass Spectrometry, 218-219 (2009)
A capillary GC method using nitrogen phosphorus detection for determination of topiramate in patients with epilepsy.
Malakova, J., et al.
Chromatographia, 66, 363-367 (2007)