SMILES string
Cc1c2ccccc2c(C)c3c1ccc4ccccc34
InChI
1S/C20H16/c1-13-16-8-5-6-9-17(16)14(2)20-18(13)12-11-15-7-3-4-10-19(15)20/h3-12H,1-2H3
InChI key
ARSRBNBHOADGJU-UHFFFAOYSA-N
grade
certified reference material, TraceCERT®
packaging
ampule of 1 mL
concentration
1000 μg/mL in methanol
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
application(s)
environmental
format
single component solution
storage temp.
2-8°C
Quality Level
General description
7,12-Dimethylbenz[a]anthracene is a polyaromatic hydrocarbon, which is a pollutant that can be released into the environment due to incomplete combustion.
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Other Notes
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Legal Information
TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany
signalword
Danger
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Flam. Liq. 2 - STOT SE 1
target_organs
Eyes,Central nervous system
存储类别
3 - Flammable liquids
wgk
WGK 3
flash_point_f
49.5 °F - Methanol
flash_point_c
9.7 °C - Methanol
法规信息
危险化学品
此项目有
Bioprotective Efficacy of Erucin Against 7, 12-Dimethylbenz (?) anthracene-Induced Microstructural Changes in Male Wistar Rats
Mannan R, et al.
Turkish Journal of Pathology, 33, 150-156 (2017)
Jitender Monga et al.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 31(4), 313-323 (2013-02-12)
The objective of this study was to investigate the chemopreventive potential of (+)-catechin-rich extract of Acacia catechu heartwood (AQCE) against 7,12-dimethylbenz[a]anthracene (DMBA)-induced hepatocellular carcinoma in Balb/c mice. The levels of liver injury markers, tumor markers, and oxidative stress were measured
Jennifer M Watson et al.
Lasers in surgery and medicine, 45(3), 155-166 (2013-01-31)
Ovarian cancer has an extremely high mortality rate resulting from poor understanding of the disease. In order to aid understanding of disease etiology and progression, we identify the endogenous fluorophores present in a mouse model of ovarian cancer and describe
Norman Sachs et al.
Proceedings of the National Academy of Sciences of the United States of America, 109(52), 21468-21473 (2012-12-14)
Progression through the various stages of skin tumorigenesis is correlated with an altered expression of the integrin α3β1, suggesting that it plays an important role in the tumorigenic process. Using epidermis-specific Itga3 KO mice subjected to the 7,12-dimethylbenzanthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate two-stage
S Manoharan et al.
Asian Pacific journal of cancer prevention : APJCP, 13(11), 5753-5757 (2013-01-16)
Apoptosis, also known as cell suicide or programmed cell death, removes unwanted and genetically damaged cells from the body. Evasion of apoptosis is one of the major characteristic features of rapidly proliferating tumor cells. Chemopreventive agents inhibit or suppress tumor
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