59357-U40
Discovery® Cyano (5 µm) HPLC Columns
L × I.D. 25 cm × 4 mm, HPLC Column
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关于此项目
UNSPSC Code:
41115700
eCl@ss:
32110501
NACRES:
SB.52
L × i.d.:
25 cm × 4 mm
Particle size:
5 μm
Matrix active group:
cyano phase
Pore size:
180 Å
Matrix:
silica gel, high purity, spherical base material, fully porous particle
产品名称
Cyano HPLC 色谱柱 ®, 5 μm particle size, L × I.D. 25 cm × 4 mm
material
stainless steel column
agency
suitable for USP L10
product line
Discovery®
feature
endcapped
manufacturer/tradename
Discovery®
packaging
1 ea of
extent of labeling
4.5% Carbon loading
parameter
≤70 °C temp. range, 400 bar pressure (5801 psi)
technique(s)
HPLC: suitable, LC/MS: suitable
L × I.D.
25 cm × 4 mm
surface area
200 m2/g
surface coverage
3.5 μmol/m2
impurities
<10 ppm metals
matrix
silica gel, high purity, spherical base material, fully porous particle
matrix active group
cyano phase
particle size
5 μm
pore size
180 Å
operating pH range
2-8
application(s)
food and beverages
separation technique
hydrophilic interaction (HILIC), normal phase, reversed phase
Quality Level
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Features and Benefits
- 低疏水性可实现对疏水性化合物的快速洗脱
- 分析强碱性化合物具有优良的峰形和保留性能
- 对极性化合物具有较强的保留能力
- 独特的选择性
- 保留时间显著小于 C18 柱（通常流动相中所需有机相比例更低）
- 稳定性好、低流失，适用于 LC-MS 分析
- 与高含水量的流动相兼容
Legal Information
Discovery is a registered trademark of Merck KGaA, Darmstadt, Germany
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Two classes of molecules were designed and synthesized based on a 6-CH(3) cyclopenta[d]pyrimidine scaffold and a pyrrolo[2,3-d]pyrimidine scaffold. The pyrrolo[2,3-d]pyrimidines were synthesized by reacting ethyl 2-cyano-4,4-diethoxybutanoate and acetamidine, which in turn was chlorinated and reacted with the appropriate anilines to
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A novel series of pyrazolines 2 have been designed, synthesized, and evaluated by in vivo screening as tissue-selective androgen receptor modulators (SARMs). Structure-activity relationships (SAR) were investigated at the R1 to R6 positions as well as the core pyrazoline ring
Graciela B Arhancet et al.
Journal of medicinal chemistry, 53(16), 5970-5978 (2010-08-03)
A new 1,4-dihydropyridine 5a, containing a cyano group at the C3 position, was recently reported to possess excellent mineralocorticoid receptor (MR) antagonist in vitro potency and no calcium channel-blocker (CCB) activity. In the present study, we report the structure-activity relationships
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