This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.comSpiroxamine is a systemic fungicide that belongs to the class of synthetic amines or morpholines. It targets the ∆14-reductase enzyme and inhibits sterol biosynthesis. It is used against powdery mildew, rust, and spot fungi on cereals and grapes for its protective, curative, and eradicative activities.
As per Regulation (EC) No. 1107/2009, repealing directive 91/414/EEC, spiroxamine is approved for use in the European Union (EU). A maximum residue limit (MRL) of 0.01 mg/kg and 0.05 mg/kg is applicable for the presence of spiroxamine in fresh/frozen fruits and tree nuts respectively, in accordance with Regulation (EC) No. 2016/452. Spiroxamine is to be monitored in the Multiannual Control Programme for Pesticides Residues (MACP), run within the EU and EFTA in/on products of plant origin.

The certified reference material (CRM) is intended to be used as a calibrant for chromatography and other analytical techniques.
The spiroxamine CRM may also find the following uses:

• Development of an enantioselective method to determine three fungicide residues in grapevine, sugar beet, and wheat samples by gas chromatography-tandem mass spectrometry (GC-MS/MS)
• Quantification of 19 neonicotinoids and fungicides from pollen and individual bumblebee samples using modified QuEChERS extraction with ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS)
• Evaluation of a gas chromatographic method with electron capture and nitrogen phosphorus detection (GC/ECD/NPD) for the analysis of 46 pesticides in fresh peppermint samples
• Multi-residue determination of 25 pesticide residues in red wine by gas chromatography-mass spectrometry(GC-MS)
• QuEChERS extraction and liquid chromatography-tandem mass spectrometry based determination of 42 pesticides in six marijuana samples
• Investigation of three different sample preparation methods to select the most suitable one for the analysis of 98 pesticides in globe artichoke leaves and fruit samples by LC-MS and GC-MS

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany