V000590
2-巯基乙醇
99.0%
别名:
β-巯基乙醇, 2-羟乙基硫醇, BME, 硫代二甘醇
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线性分子式:
HSCH2CH2OH
化学文摘社编号:
分子量:
78.13
EC Number:
200-464-6
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
773648
InChI key
DGVVWUTYPXICAM-UHFFFAOYSA-N
InChI
1S/C2H6OS/c3-1-2-4/h3-4H,1-2H2
SMILES string
OCCS
grade
synthesis grade
vapor density
2.69 (vs air)
vapor pressure
1 mmHg ( 20 °C)
assay
99.0%
expl. lim.
18 %
concentration
14.3 M (pure liquid)
Quality Level
bp
157 °C (lit.)
density
1.114 g/mL at 25 °C (lit.)
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Application
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
signalword
Danger
Hazard Classifications
Acute Tox. 2 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Repr. 2 - Skin Irrit. 2 - Skin Sens. 1A - STOT RE 2 Oral
target_organs
Liver,Heart
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
165.2 °F - closed cup
flash_point_c
74 °C - closed cup
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