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Merck
CN

V000600

刚果红

别名:

刚果红 4B, 棉红 B, 棉红 C, 煮大红, 直接红 28, 直接红 R, 直接红 Y

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关于此项目

经验公式(希尔记法):
C32H22N6Na2O6S2
化学文摘社编号:
分子量:
696.66
PubChem Substance ID:
EC Number:
209-358-4
Beilstein/REAXYS Number:
3894858
Colour Index Number:
22120
MDL number:
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SMILES string

[Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O

InChI

1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;

InChI key

IQFVPQOLBLOTPF-HKXUKFGYSA-L

mp

>360 °C (lit.)

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pictograms

Health hazard

signalword

Danger

Hazard Classifications

Carc. 1B - Repr. 2

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

法规信息

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Rapidly progressive obstructive jaundice due to Congo red negative amyloidosis.
B M McClements et al.
The Ulster medical journal, 60(2), 229-234 (1991-10-01)
Hideyo Inouye et al.
Sub-cellular biochemistry, 38, 203-224 (2005-02-16)
We consider here the chemistry of Congo red (CR), its binding equilibrium to Alzheimer's beta-amyloid, and the kinetics of beta-amyloid formation. Spectroscopic UV/V is measurements for the pH- and time-dependence binding of CR to Abeta analogues are analysed by Scatchard
Nibaldo C Inestrosa et al.
Current Alzheimer research, 2(3), 301-306 (2005-06-25)
The cholinergic system impairment observed in Alzheimer's disease (AD) patients leads to the cognitive, global and behavioral dysfunction commonly associated with dementia. The only treatment for AD has been the use of inhibitors of acetylcholinesterase (AChE) (E.C. 3.1.1.7), which is
Alexander J Howie et al.
Micron (Oxford, England : 1993), 40(3), 285-301 (2008-11-21)
Amyloid stained by Congo red has striking optical properties that generally have been poorly described and inadequately explained, although they can be understood from principles of physical optics. Molecules of Congo red are orientated on amyloid fibrils, and so the
Biomedicine. Proteins and a pregnancy woe.
Nadia Whitehead
Science (New York, N.Y.), 345(6194), 249-249 (2014-07-19)

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