V900331
6-O-棕榈酰-L-抗坏血酸
Vetec™, reagent grade, 95%
别名:
L-抗坏血酰棕榈酸酯, L-抗坏血酸 6-十六烷酸酯, NSC 402451, 抗坏血酸6-棕榈酸酯
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关于此项目
经验公式（希尔记法）:
C22H38O7
化学文摘社编号:
分子量:
414.53
Beilstein:
96552
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
等级
reagent grade
产品线
Vetec™
方案
95%
表单
powder
颜色
light yellow
mp
107-117 °C
SMILES字符串
CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O
InChI
1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1
InChI key
QAQJMLQRFWZOBN-LAUBAEHRSA-N
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一般描述
Palmitoyl-L-ascorbic acid, also known as, ascorbyl palmitate, is the lipid-soluble variant of Vitamin C. It is located on the cellular membranes.
生化/生理作用
Ascorbyl palmitate is widely used in the food industry as an additive and antioxidant. Prior to absorption in the digestive tract, ascorbyl palmitate is catabolized to ascorbic acid and palmitic acid. Ascorbyl palmitate rescues human aortic smooth muscle cells (AoSMC) and aids in overcoming the collagen deposition inhibition by nifedipine. Ascorbic acid-6-palmitate, in the presence of ultraviolet B (UVB), favors lipid peroxidation leading to cytotoxicity in epidermal cells.
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Inhibition of collagen synthesis by select calcium and sodium channel blockers can be mitigated by ascorbic acid and ascorbyl palmitate
Ivanov V, et al.
American Journal of Cardiovascular Disease, 6(2), 26-26 (2016)
Antioxidant role of ascorbic acid and his protective effects on chronic diseases
Oxidative Stress and Chronic Degenerative Diseases-A Role for Antioxidants, 449-449 (2013)
Vitamin C derivative ascorbyl palmitate promotes ultraviolet-B-induced lipid peroxidation and cytotoxicity in keratinocytes
Meves A, et al.
The Journal of Investigative Dermatology, 119(5), 1103-1108 (2002)
Mirjam Gosenca et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 50(1), 114-122 (2013-05-07)
Liquid crystalline systems with a lamellar structure have been extensively studied as dermal delivery systems. Ascorbyl palmitate (AP) is one of the most studied and used ascorbic acid derivatives and is employed as an antioxidant to prevent skin aging. The
P O Nnamani et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(1), 68-74 (2010-06-18)
P90Gylation refers to the modification of lipid molecules by one or more phospholipid chains. Phospholipon 90G (P90G) contains about 94.0% of phosphatidylcholine stabilized with 0.1% ascorbyl palmitate and is a safe (GRAS) FDA-approved parenteral excipient with wide applications in drug
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