V900411
组胺 二盐酸盐
Vetec™, reagent grade, 98%
别名:
2-(4-咪唑)乙胺 二盐酸盐
等级
reagent grade
产品线
Vetec™
方案
98%
mp
249-252 °C (lit.)
储存温度
2-8°C
SMILES字符串
Cl[H].Cl[H].NCCc1c[nH]cn1
InChI
1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
InChI key
PPZMYIBUHIPZOS-UHFFFAOYSA-N
基因信息
human ... HRH1(3269)
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生化/生理作用
内源性 H1 和 H2 组胺受体激动剂;可活化一氧化氮合成酶;有效的血管舒张剂。
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
警示用语：
Danger
危险分类
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
储存分类代码
11 - Combustible Solids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Yuki Bessho et al.
Neuroscience letters, 578, 106-110 (2014-07-06)
In mammals, it is established that histamine is a neurotransmitter and/or neuromodulator in the central nervous system. It is produced by the enzyme histidine decarboxylase (HDC) in the tuberomammillary nucleus of the posterior hypothalamus. However, HDC as well as histaminergic
Chayon Goswami et al.
PloS one, 10(6), e0131554-e0131554 (2015-06-27)
Motilin and ghrelin constitute a peptide family, and these hormones are important for the regulation of gastrointestinal motility. In this study, we examined the effect of motilin and ghrelin on gastric acid secretion in anesthetized suncus (house musk shrew, Suncus
Kevin B Freeman et al.
Psychopharmacology, 231(12), 2395-2403 (2014-01-09)
Recent research has demonstrated that the drug, histamine, can function as a punisher of cocaine self-administration. However, little is known about how drug punishers affect the maximum reinforcing effectiveness of drugs as reinforcers. The goal of the present study was
Guadalupe-Elide Morales-Figueroa et al.
ACS chemical neuroscience, 5(8), 637-645 (2014-06-03)
High levels of histamine H3 receptors (H3Rs) are found in the globus pallidus (GP), a neuronal nucleus in the basal ganglia involved in the control of motor behavior. By using rat GP isolated nerve terminals (synaptosomes), we studied whether H3R
Carlos Daniel Zappia et al.
Scientific reports, 5, 17476-17476 (2015-12-05)
Histamine H1 receptor (H1R) antagonists and glucocorticoid receptor (GR) agonists are used to treat inflammatory conditions such as allergic rhinitis, atopic dermatitis and asthma. Consistent with the high morbidity levels of such inflammatory conditions, these receptors are the targets of
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