V900491
3-吲哚丙酸
Vetec™, reagent grade, 99%
别名:
3-(3-吲哚基)丙酸, IPA, NSC 3252, NSC 47831, 吲哚-3-丙酸
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关于此项目
经验公式（希尔记法）:
C11H11NO2
化学文摘社编号:
分子量:
189.21
EC Number:
212-600-1
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
147733
MDL number:
InChI key
GOLXRNDWAUTYKT-UHFFFAOYSA-N
InChI
1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)
SMILES string
OC(=O)CCc1c[nH]c2ccccc12
grade
reagent grade
product line
Vetec™
assay
99%
mp
134-135 °C (lit.)
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Application
反应物用于制备：
- 独脚金内酯的荧光类似物
- 抗肿瘤剂
- 黑皮质素受体配体
- 免疫抑制剂
- 丙肝病毒抑制剂
- 组胺H4受体激动剂
- NR2B/NMDA受体拮抗剂
- CB1拮抗剂用于治疗肥胖症免疫抑制剂
- 抗细菌剂
- TGF-β受体结合抑制剂
Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Youjia Yu et al.
Frontiers in physiology, 11, 65-65 (2020-03-03)
Paraquat (PQ) is a widely used herbicide which can cause high mortality to humans. However, relatively few studies focus on metabolic feature of PQ intoxication for investigating the underlying mechanisms. Here we performed non-targeted metabolomics profiling of serum samples from
Indole-3-propionic acid attenuates neuronal damage and oxidative stress in the ischemic hippocampus.
In Koo Hwang et al.
Journal of neuroscience research, 87(9), 2126-2137 (2009-02-25)
Tryptophan-derived indole compounds have been widely investigated as antioxidants and as free-radical scavengers. Indole-3-propionic acid (IPA), one of these compounds, is a deamination product of tryptophan. In the present study, we used Mongolian gerbils to investigate IPA's neuroprotective effects against
Burkhard Poeggeler et al.
PloS one, 5(4), e10206-e10206 (2010-04-28)
Aging is a multi-factorial process, however, it is generally accepted that reactive oxygen species (ROS) are significant contributors. Mitochondria are important players in the aging process because they produce most of the cellular ROS. Despite the strength of the free-radical
K L Borden et al.
European journal of biochemistry, 202(2), 459-470 (1991-12-05)
The antirepressor indole 3-propanoate has been shown by X-ray crystallography to bind in a different orientation compared with the natural corepressor for the tryp repressor, L-tryptophan (Lawson, C.L. & Sigler, P. B. (1988) Nature 333, 869-871). This suggests a simple
M Karbownik et al.
Journal of cellular biochemistry, 81(3), 507-513 (2001-03-20)
Excessive free iron and the associated oxidative damage are commonly related to carcinogenesis. Among the antioxidants known to protect against iron-induced oxidative abuse and carcinogenesis, melatonin and other indole compounds recently have received considerable attention. Indole-3-propionic acid (IPA), a deamination
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