V900491
3-吲哚丙酸
Vetec™, reagent grade, 99%
别名:
3-(3-吲哚基)丙酸, IPA, NSC 3252, NSC 47831, 吲哚-3-丙酸
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关于此项目
经验公式（希尔记法）:
C11H11NO2
化学文摘社编号:
分子量:
189.21
Beilstein:
147733
EC 号:
MDL编号:
UNSPSC代码:
12352100
PubChem化学物质编号:
等级
reagent grade
产品线
Vetec™
方案
99%
mp
134-135 °C (lit.)
SMILES字符串
OC(=O)CCc1c[nH]c2ccccc12
InChI
1S/C11H11NO2/c13-11(14)6-5-8-7-12-10-4-2-1-3-9(8)10/h1-4,7,12H,5-6H2,(H,13,14)
InChI key
GOLXRNDWAUTYKT-UHFFFAOYSA-N
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应用
反应物用于制备：
- 独脚金内酯的荧光类似物
- 抗肿瘤剂
- 黑皮质素受体配体
- 免疫抑制剂
- 丙肝病毒抑制剂
- 组胺H4受体激动剂
- NR2B/NMDA受体拮抗剂
- CB1拮抗剂用于治疗肥胖症免疫抑制剂
- 抗细菌剂
- TGF-β受体结合抑制剂
法律信息
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Youjia Yu et al.
Frontiers in physiology, 11, 65-65 (2020-03-03)
Paraquat (PQ) is a widely used herbicide which can cause high mortality to humans. However, relatively few studies focus on metabolic feature of PQ intoxication for investigating the underlying mechanisms. Here we performed non-targeted metabolomics profiling of serum samples from
Paul E Bendheim et al.
Journal of molecular neuroscience : MN, 19(1-2), 213-217 (2002-09-06)
The accumulation of amyloid-beta and concomitant oxidative stress are major pathogenic events in Alzheimer's disease. Indole-3-propionic acid (IPA, OXIGON) is a potent anti-oxidant devoid of pro-oxidant activity. IPA has been demonstrated to be an inhibitor of beta-amyloid fibril formation and
Qiaomei Lu et al.
Rapid communications in mass spectrometry : RCM, 22(16), 2565-2572 (2008-07-26)
Auxin is an important phylohormone, which regulates specific physiological responses such as division, elongation and differentiation of cells. A new method using liquid chromatography/electrospray ionization ion trap mass spectrometry (LC/ESI-ITMS) has been developed for identification and quantitation of four auxins.
Y J Chyan et al.
The Journal of biological chemistry, 274(31), 21937-21942 (1999-07-27)
Widespread cerebral deposition of a 40-43-amino acid peptide called the amyloid beta-protein (Abeta) in the form of amyloid fibrils is one of the most prominent neuropathologic features of Alzheimer's disease. Numerous studies suggest that Abeta is toxic to neurons by
Bernd Kuhn et al.
Bioorganic & medicinal chemistry letters, 16(15), 4016-4020 (2006-06-02)
In the quest for novel PPARalpha/gamma co-agonists as putative drugs for the treatment of type 2 diabetes and dyslipidemia, we have used a structure-based design approach to identify propionic acids with a 1,5-disubstituted indole scaffold as potent PPARalpha/gamma activators. Compounds
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