V900570
2,3,5,6-四甲基吡嗪
Vetec™, reagent grade, 98%
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关于此项目
经验公式（希尔记法）:
C8H12N2
化学文摘社编号:
分子量:
136.19
EC Number:
214-391-2
UNSPSC Code:
12352100
PubChem Substance ID:
Beilstein/REAXYS Number:
113100
MDL number:
Assay:
98%
InChI key
FINHMKGKINIASC-UHFFFAOYSA-N
InChI
1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
SMILES string
Cc1nc(C)c(C)nc1C
grade
reagent grade
product line
Vetec™
assay
98%
bp
190 °C (lit.)
mp
77-80 °C (lit.)
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Legal Information
Vetec is a trademark of Merck KGaA, Darmstadt, Germany
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Xuesong Zhang et al.
Journal of cellular physiology (2019-02-17)
Inadequate oxygen supply is probably one of the most important pathophysiological mechanisms of cardiomyocyte damage in ischemic heart disease. Tetramethylpyrazine (TMP, also known as ligustrazine) is the main active ingredient isolated from the rhizome of Ligusticum chuanxiong Hort. A previous
Penglong Wang et al.
Die Pharmazie, 68(9), 782-789 (2013-10-24)
A new anticancer ligustrazine derivative, 3beta-hydroxyolea-12-en-28-oic acid-3,5,6-trimethylpyrazin-2-methyl ester (T-OA, C38H58O3N2), was previously reported. It was synthesized via conjugating the effective antitumor ingredients of a classic traditional Chinese medicine (TCM) formulation. In the present study, anticancer efficacy of T-OA was evaluated
Yaogui Sun et al.
Pharmaceutical biology, 51(9), 1137-1143 (2013-04-24)
The prevalence of infectious bursal disease has brought about enormous financial losses to the world poultry industry. Chinese herb medicines can provide valuable materials for discovery and development of new drugs. To screen constituents derived from Chinese herb medicines for
Yu-Fang Leng et al.
The American journal of Chinese medicine, 40(6), 1229-1239 (2012-12-12)
The Bennett and Xie (1988) model of chronic constriction injury (CCI) investigated the effects of tetramethylpyrazine (TMP) on neuropathic pain-associated behaviors and neuronal apoptosis in the spinal dorsal horn. Fifty-four male rats were randomly divided into sham (group S), CCI
Lijun Wei et al.
International journal of pharmaceutics, 437(1-2), 203-212 (2012-09-05)
Ligustrazine is a traditional Chinese medicine used to treat various cardiovascular and neurovascular complications. However, this compound exhibits rapid first-pass metabolism, a short biological half-life, low stability and potential vascular irritation that restrict its use for long-term therapy. The use
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