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Merck
CN

V900919

两性霉素B 来源于链霉菌

suitable for cell culture, Vetec, BioReagent

别名:

两性霉素B 来源于链霉菌 属, Fungizone

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关于此项目

经验公式(希尔记法):
C47H73NO17
化学文摘社编号:
分子量:
924.08
UNSPSC Code:
12352207
PubChem Substance ID:
EC Number:
215-742-2
Beilstein/REAXYS Number:
78342
MDL number:
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产品名称

两性霉素B 来源于链霉菌 属, Vetec, reagent grade, BioReagent, suitable for cell culture, ~80%

InChI

1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1

InChI key

APKFDSVGJQXUKY-INPOYWNPSA-N

SMILES string

C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O

grade

reagent grade

product line

BioReagent
Vetec

assay

~80%

technique(s)

cell culture | mammalian: suitable

antibiotic activity spectrum

fungi
yeast

mode of action

cell membrane | interferes

storage temp.

2-8°C

Quality Level

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Biochem/physiol Actions

两性霉素B可与甾醇结合,在膜中形成孔,并导致小分子的泄漏。该产品对真菌和酵母最有效。
两性霉素B可用于急性侵袭性真菌感染的初级治疗,例如曲霉菌病。

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

pictograms

Health hazard

signalword

Danger

hcodes

Hazard Classifications

STOT RE 1

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis.
Herbrecht R, et al.
The New England Journal of Medicine, 347(6), 408-415 (2002)
Randomized, double-blind clinical trial of amphotericin B colloidal dispersion vs. amphotericin B in the empirical treatment of fever and neutropenia.
White MH, et al.
Clinical Infectious Diseases, 27(2), 296-302 (1998)
Chitralekha Mohanty et al.
Anticancer research, 34(6), 2801-2806 (2014-06-13)
The use of ion radiation therapy is growing due to the continuously increasing positive clinical experience obtained. Therefore, there is a high interest in radio-biological experiments comparing the relative efficiency in cell killing of ions and photons as photons are
Malav S Trivedi et al.
The Journal of nutritional biochemistry, 25(10), 1011-1018 (2014-07-16)
Dietary interventions like gluten-free and casein-free diets have been reported to improve intestinal, autoimmune and neurological symptoms in patients with a variety of conditions; however, the underlying mechanism of benefit for such diets remains unclear. Epigenetic programming, including CpG methylation
Rujiu Hu et al.
Journal of animal science and biotechnology, 12(1), 25-25 (2021-02-18)
Lactobacillus reuteri strains are widely used as probiotics to prevent and treat inflammatory bowel disease by modulating the host's immune system. However, the underlying mechanisms by which they communicate with the host have not been clearly understood. Bacterial extracellular vesicles

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