跳转至内容
Merck
CN

V900926

氟维司群

Vetec™, reagent grade, >98%

别名:

氟维司群, (7α,17β)-7-[9-[(4,4,5,5,5-五氟戊基)亚磺酰基]壬基]雌-1,3,5(10)-三烯-3,17-二醇, ICI 182,780, ZD 182780, ZD 9238, ZM 182780, 与法洛德

登录 查看组织和合同定价。

选择尺寸

关于此项目

经验公式（希尔记法）:
C32H47F5O3S
化学文摘社编号:
129453-61-8
分子量:
606.77
UNSPSC Code:
12352200
PubChem Substance ID:
329830230
MDL number:
MFCD00903953

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

InChI

1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1

SMILES string

[H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc4cc(O)ccc24

InChI key

VWUXBMIQPBEWFH-WCCTWKNTSA-N

grade

reagent grade

product line

Vetec™

assay

>98%

storage temp.

2-8°C

Gene Information

human ... ESR1(2099), ESR2(2100)

正在寻找类似产品? 访问 产品对比指南

Biochem/physiol Actions

氟维司群是一种选择性雌激素受体下调剂（SERD）；具有高亲和力的雌激素受体拮抗剂。
氟维司群（ICI 182,780）是一种选择性雌激素受体下调剂（SERD）。氟维司群是一种具有高亲和力的雌激素受体拮抗剂。IC50 = 0.29 nM。氟维司群是第一种“纯”抗雌激素，在体外和体内均无激动活性。

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

wgk

WGK 3

Hazard Classifications

Aquatic Chronic 1 - Lact. - Repr. 1B

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

pictograms

Health hazardEnvironment
GHS08,GHS09

signalword

Danger

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

监管及禁止进口产品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
WXBF1898V
WXBD7227V
WXBD3304V
WXBC9975V
WXBC6882V

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Haimei Li et al.
Life sciences, 344, 122581-122581 (2024-03-22)
Hypocretin is synthesized exclusively in the hypothalamus and distributes inputs to several areas of the brain, which may play an important role in depression. Our previous study showed that hypocretin-1 was increased in the lateral hypothalamus in female patients with
Meng-Yuan Li et al.
Cells, 13(3) (2024-02-09)
(1) Background: Inflammatory responses are implicated in embryo implantation, decidualization, pregnancy maintenance and labor. Both embryo implantation and decidualization are essential to successful pregnancy in rodents and primates. S100A6 is involved in inflammation, tumor development, apoptosis and calcium homeostasis. S100A6
Jieyu He et al.
Aging medicine (Milton (N.S.W)), 6(4), 379-385 (2024-01-19)
To investigate the relationship between icariin and the osteoblastic differentiation of vascular smooth muscle cells (VSMCs) and the signal pathway involved. We applied a universally accepted calcification model of VSMCs induced by β glycerophosphate. Then the VSMCs calcification was observed
Yuet-Kin Leung et al.
PloS one, 9(5), e98037-e98037 (2014-05-20)
Fulvestrant (ICI-182,780) has recently been shown to effectively suppress prostate cancer cell growth in vitro and in vivo. But it is unclear whether microRNAs play a role in regulating oncogene expression in fulvestrant-treated prostate cancer. Here, this study reports hsa-miR-765
Ke-Wei Zhang et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 237, 110328-110328 (2019-08-29)
Insulin-like growth factors (Igf1 and Igf2) play a key role in growth and development of vertebrates. In mammals, the expression of IGFs is regulated by estradiol-17β (E2) via estrogen receptors (ESRs). The expression of igfs can also be regulated by
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持