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Wasim Ahmad et al.
Journal of chromatographic science, 52(8), 911-918 (2013-08-28)
Safoof-e-Pathar phori (SPP) is a traditional polyherbal formulation and has been used since long time for its anti-urolithiatic activity. It contains three plant constituents Didymocarpous pedicellata, Dolichous biflorus and Rheum emodi. Emodin and chrysophanic acid were selected as chemical markers
Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV.
Liu R
Journal of Pharmaceutical and Biomedical Analysis, 43(3), 1007-1012 (2007)
Xue-ru Zhang et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 45(9), 1144-1148 (2011-03-01)
Through our pre-investigation and literature analysis, it was found that rhubarb could be categorized into two types, chrysophanol-type and rhein-type, based on the proportion of the two constituents in the total content of anthraquinones after acid hydrolysis. In this paper
Xiaoping Huang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 35(16), 2065-2067 (2010-11-05)
To improve the determination method of Cassiae Semen in China Pharmacopeia edition 2005. MMETHOD: Aurantio-obtusin and chrysophanol were separated on an Inertsil ODS-3 column with acetonitrile-0.1% phosphoric acid solutiona as mobile phase in gradient elution. The linear ranges of aurantio-obtusin
Zhi-Xiong Zhang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(9), 1371-1373 (2012-01-21)
To study the chemical constituents root of Hemerocallis citrina. The chemical constituents were extracted by microwave method and purified by silica gel column. Their structures were elucidated by their physical and chemical properties and spectral methods. 7 compounds were isolated
Shu-Jen Chang et al.
Archives of pharmacal research, 37(9), 1117-1123 (2014-01-08)
Rheum palmatum, Chinese traditional herb, exhibits a great variety of anti-cancer and anti-viruses properties. This study rates antiviral activity of R. palmatum extracts and its components against Japanese encephalitis virus (JEV) in vitro. Methanol extract of R. palmatum contained higher
Fang Fang et al.
Journal of ethnopharmacology, 137(3), 1492-1497 (2011-09-03)
The present study comparatively investigated the tissue distributions of rhubarb anthraquinone derivatives (AQs) to examine whether they undergo different uptakes in normal or CCl(4)-induced liver-damaged rats, to explore possible reasons for the different toxicities of AQs in pathological model rats
Chrysophanol, an antimicrobial anthraquinone from the root extract of Colubrina greggii.
Garcia-Sosa, Karlina, et al.
Journal of the Mexican Chemical Society, 50.2, 76-78 (2006)
Chien-Hang Ni et al.
Archives of pharmacal research, 35(5), 887-895 (2012-05-31)
Liver cancer is the most common form of cancer in Taiwan and it usually responds to chemotherapy. However, patients often have side effects to the chemotherapeutic drugs. Thus new agents are urgently required to treat liver cancer. Chrysophanol, one of
Myung Sun Lee et al.
Phytotherapy research : PTR, 25(6), 833-837 (2010-11-23)
Inactivation of epidermal growth factor receptor (EGFR) is a prime method used in colon cancer therapy. Here it is shown that chrysophanic acid, a natural anthraquinone, has anticancer activity in EGFR-overexpressing SNU-C5 human colon cancer cells. Chrysophanic acid preferentially blocked
Yuying Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(2), 212-217 (2012-06-29)
To establish a quality evaluation method, quantitative analysis of multi-component with a single-marker (QAMS) to determine the contents of four rhubarb anthraquinones in Sanhuang tablets. Emodin was used as the internal reference substance, the relative correlation factors (RCF) of rhein
De-lin Wu et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 34(7), 1055-1057 (2011-11-10)
To investigate the chemical constituents of Carya cathayensis and their antitumor bioactivity. The compounds were isolated by Sephadex LH-20 and silica gel column chromatography. Their structures were identified by physicochemical properties and spectroscopic analysis. Then their cytotoxic activity was studied.
Jackson Roberto Guedes da Silva Almeida et al.
TheScientificWorldJournal, 2012, 859210-859210 (2012-05-31)
The ethanol extract from the fruits of Duguetia chrysocarpa was evaluated for its antinociceptive activity in chemical and thermal models of nociception in mice. The intraperitoneal administration of the ethanol extract (100, 200, and 400 mg/kg body weight) showed a
Lijia Xu et al.
Phytochemical analysis : PCA, 23(2), 110-116 (2011-05-28)
Semen Cassiae (SC), a traditional Chinese herbal medicine for the treatment of various diseases, is known to contain active anthraquinone ingredients. However, since the content of some anthraquinones is too low, previous analytical methods only allow the quantitation of a
Li Chu et al.
DNA and cell biology, 34(3), 178-188 (2015-01-22)
The traditional Chinese medicinal formula BDL301 has been used to inhibit inflammation for hundreds of years. The development of colorectal cancer and chronic inflammation are closely related. In this study, we investigated whether BDL301 could inhibit tumor growth. We found
Chu VanMen et al.
Phytochemical analysis : PCA, 23(4), 359-364 (2011-10-20)
Rhubarb is a traditional Chinese medicine derived from the rhizome of three species: Rheum tanguticum, Rheum palmatum and Rheum officinale. There are several species that are often misidentified as rhubarb. Taxonomical identification of these various species can be challenging. We
Xiao Liu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 980, 88-93 (2015-01-20)
Most herbal medicines are prescribed in combination based on the theory of TCM to obtain synergistic effects or diminish the possible adverse reactions. Compatibility refers to the combination of two or more herbs based on the clinical settings and the
Yuanyuan Zhang et al.
Colloids and surfaces. B, Biointerfaces, 103, 94-98 (2012-12-04)
Acetylene black (AB) nanoparticles were readily dispersed into water in the presence of dihexadecyl hydrogen phosphate. After evaporation of water, the surface of glassy carbon electrode (GCE) was coated with AB nanoparticles as confirmed from the scanning electron microscopy measurements.
Hui Zhang et al.
Molecules (Basel, Switzerland), 17(1), 843-850 (2012-01-19)
An ethyl acetate extract of the roots of Rumex dentatus L. was investigated. Three compounds were identified by their spectroscopic data as chrysophanol (1), 6-methyl-7-acetyl-1, 8-dihydroxy-3-methoxy naphthalene-1-O-β-D(L)-glucoside (2) and 6-methyl-7-acetyl-1, 8-dihydroxy naphthalene-1-O-β-D(L)-glucoside (3) were found in the plant for the
Haiming Chen et al.
Biomedical chromatography : BMC, 27(9), 1092-1099 (2013-03-19)
Pogostone is an important constituent of Pogostemon cablin (Blanco) Benth., and possesses various known bioactivities. A rapid, simple and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method was developed for the analysis of pogostone in rat plasma using chrysophanol as
Chrysophanol induces necrosis through the production of ROS and alteration of ATP levels in J5 human liver cancer cells.
Lu CC
Molecular Nutrition And Food Research, 54(7), 967-976 (2010)
Zhi-sen Wang et al.
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 35(5), 699-702 (2012-12-12)
To establish a simple, rapid and usable new method of processing on Rhei Radix Et Rhizoma and the quality control standard on its processing products. The studies of processing on Rhei Radix Et Rhizoma were proceed using yellow rice wine
Tiffany Chien-Ting Lo et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 893-894, 101-106 (2012-03-23)
Chrysophanol has high pharmaceutical values. However, it was difficult to use the traditional extraction method to extract high-concentration chrysophanol. Therefore, the purpose of this study is to purify and separate chrysophanol in traditional herb, Rheum Palmatum LINN, by using supercritical
Su-Jin Kim et al.
Molecules (Basel, Switzerland), 15(9), 6436-6451 (2010-09-30)
Chrysophanol is a member of the anthraquinone family and has multiple pharmacological effects, but the exact mechanism of the anti-inflammatory effects of chrysophanol has yet to be thoroughly elucidated. In this study, we attempted to determine the effects of chrysophanol
Li-Chun Zhao et al.
Molecules (Basel, Switzerland), 16(7), 5928-5937 (2011-07-19)
In this paper, ultrasound-assisted extraction (UAE) was applied to the extraction of anthraquinones (aloe-emodin, rhein, emodin, chrysophanol and physcion) from Rheum palmatum L. The five anthraquinones were quantified and analyzed by high performance liquid chromatography coupled with UV detection (HPLC-UV).
Xian Ding et al.
Journal of medical microbiology, 60(Pt 12), 1827-1834 (2011-08-20)
The objective of this study was to screen for novel quorum-sensing inhibitors (QSIs) from traditional Chinese medicines (TCMs) that inhibit bacterial biofilm formation. Six of 46 active components found in TCMs were identified as putative QSIs based on molecular docking
H Ibrahim et al.
African journal of traditional, complementary, and alternative medicines : AJTCAM, 8(2), 140-143 (2012-01-13)
Cissus populnea has been used locally to treat many ailments such as venereal, stomach and skin infections; and also used as laxative or purgative. Economically it has been used as binder in food and in lining dye pits. This work
Ying Shi et al.
Journal of chromatography. A, 1218(42), 7655-7662 (2011-09-09)
A method for simultaneous determination of eight adulterants including two appetite suppressants, two energy expenditure-enhancing drugs, one diuretic and three cathartics in slimming functional foods by high performance liquid chromatography with electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS) was established. After samples
Shuying Guo et al.
Molecules (Basel, Switzerland), 16(2), 1201-1210 (2011-01-29)
Three anthraquinones--emodin, chrysophanol, and physcion--were successfully purified from the dichloromethane extract of the Chinese medicinal herb Rumex japonicus by high-speed counter-current chromatography (HSCCC). The extract was separated with n-hexane-ethanol-water (18:22:3, v/v/v) as the two-phase solvent system and yielded 3.4 mg
Han-Lin Gong et al.
Chinese journal of integrative medicine, 18(9), 708-713 (2012-09-01)
To investigate the effect of prescription compatibility on the pharmacokinetics of components from Dachengqi Decoction (DCQD, ) in rats. Twenty-four male rats were randomly and equally divided into the DCQD group, Dahuang (Radix et Rhizoma Rhei, Polygonaceae) group, Houpo (Magnolia
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