Pesticide residue testing of turmeric and other (dried) spices is challenging due to their complex compositions and high matrix. An efficient SPE clean-up can be achieved by a new Dual-layer cartridge.

Thermal Transitions of Homopolymers: Glass Transition & Melting Point

Literature values for the glass transition temperature, (Tg), and melting temperature, (Tm), are given for the more common homopolymers.

Improving the Chromatographic Separation of DMB-Labeled Sialic Acids for the Comparison of Biosimilars to Reference Materials

A significantly improved HPLC-fluorescence method for DMB-NANA and -NGNA, and application of this method to compare 2 candidate biosimilar therapeutic proteins to their respective RMs.

Perfluorosulfonic Acid Membranes for Fuel Cell and Electrolyser Applications

Advances in the electrochemical conversion of water to and from hydrogen and oxygen have principally been achieved through the development of new materials and by understanding the mechanisms of the degradation of proton exchange membrane fuel cells (PEMFC) during operation.

Overcoming Aggregation in Solid-phase Peptide Synthesis

The ease of assembly of a given peptide sequence is hard to predict, which makes peptide synthesis challenging. Review methods and reagents for avoiding aggregation in solid-phase peptide synthesis.

Knoevenagel Condensation Reaction

Knoevenagel Condensation is an organic reaction named after Emil Knoevenagel. It is a classic C-C bond formation reaction and a modification of the Aldol Condensation.

Simplified LC-MS/MS Method for Glyphosate, AMPA, and Glufosinate in Oat-Based Cereals

A simplified LC-MS/MS method to determine glyphosate and related compounds using a Supel™ Carbon LC U/HPLC column for stability under higher pH conditions and sufficient retention for the polar analytes in the presence of methanol as an extraction solvent.

Hexafluoroalcohol-functionalized Methacrylate Monomers for Lithographic/nanopatterning materials

To keep pace with Moore′s Law, there is a continuing need in the semiconductor industry to achieve higher circuit density in microelectronic devices.

Peptide Labeling

Chromogenic and fluorogenic derivatives are invaluable tools for biochemistry, having numerous applications in enzymology, protein chemistry, immunology and histochemistry.

Cultrex^® 3-D Culture Matrix™ Laminin I Protocol

3-D Culture Matrix™ Mouse Laminin I may be used as a gel or as a media additive to study cellular growth and differentiation in three dimensions in vitro.

MSTFA/MSTFA-d9 Derivatization of Amphetamine for GC/MS Detection and Identification

Example displays how MSTFA/MSTFA-d9 derivatization of amphetamine provides valuable information in mass spectra and chromatograms using SLB-5ms GC column.

384- vs. 96-Well Multiplex Analysis of Low-Level Cytokines | MILLIPLEX^® Assays

High sensitivity multiplex panels allow researchers to detect low-level cytokines and study multiple cytokines at once to dive deeper into low-level inflammation processes. See a performance comparison of the 384-well assay and the 96-well assay formats for the MILLIPLEX® Human

Ionic Liquids

Ionic Liquids have experienced a comet-like boost in the last few years. In this edition of ChemFiles, we highlight some current applications of this fascinating class of new materials. We present over 50 new additions to our portfolio of 130+

A Serum-Free and Feeder-Free Defined Medium That Enables Weekend-Free Culture of Undifferentiated Human ES/iPS Cells

Skip weekend feedings. Defined serum-free and feeder-free expansion media for human pluripotent stem cells (ES and iPS cells). See publications and protocols.

Immunohistochemistry: Current Applications in Skin Cancer

Immunohistochemistry (IHC) techniques and applications have greatly improved, dermatopathology is still largely based on H&E stained slides.This paper outlines ways in which IHC antibodies can be utilized for dermatopathology.

Nanoparticle-Based Drug and Gene Delivery for Tumor Targeting

Professor Yoshiki Katayama (Kyushu University, Japan) discusses recent advances in drug delivery systems and strategies that exploit the EPR effect, with a special focus on stimuli-responsive systems based on novel materials.

Highly Efficient Nanoscale Inorganic Light Harvesters for Dye-sensitized Solar Cells

Since the first report of the low-cost dye-sensitized solar cell (DSSC) in 1991 by Gratzel and his coworker,1 dye-sensitized solar cells (DSSC) has been regarded as one of the most promising photovoltaic technologies because of their transparent and colorful characteristics

Chemical Synthesis of Monodisperse Magnetic Nanoparticles

Magnetic nanoparticles have attracted tremendous attention due to their novel properties and their potential applications in magnetic recording, magnetic energy storage and biomedicine.

Using Probe-Based Quantitative PCR (Qpcr) to Measure Gene-Level Expression

Quantitative PCR (qPCR) provides information about gene expression, gene amplification or loss, and small alterations. qPCR is often used to investigate tumor biology and to discover the genetic and epigenetic causes of cancer

Calcitonin Gene-Related Peptides

Sigma-Aldrich offers many products related to calcitonin gene-related peptides for your research needs.

Chitosan: A Versatile Platform for Pharmaceutical Applications

The development of new medical devices and pharmaceuticals plays an integral role in the medical industry. Both natural and synthetic polymers possess benefits that make them valuable components in therapeutics.

Reversible Addition Fragmentation Chain Transfer (RAFT) Polymerization

RAFT (Reversible Addition Fragmentation chain Transfer) polymerization is a reversible deactivation radical polymerization (RDRP) and one of the more versatile methods for providing living characteristics to radical polymerization.

Zinc Finger Nuclease References

Zinc Finger Nuclease References: Human, Rat, Mouse, Zebrafish, Plasmodium, Xenopus, Rainbow Trout, Mosquito, Pig, Rabbit, Cattle, CHO, ZFN Technology, Reviews, Posters, Label License

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