108-58-7

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Low-affinity signature of the rat beta-parvalbumin CD site. Evidence for remote determinants.

Michael T Henzl et al.

Biochemistry, 46(1), 23-35 (2007-01-03)

Although rat beta-parvalbumin and chicken parvalbumin 3 (CPV3) are identical at 74 of 108 residues, rat beta exhibits perceptibly lower Ca2+ and Mg2+ affinities. At 25 degrees C, in Hepes-buffered saline, at pH 7.4, the overall deltadeltaG degrees ' values

Screening rectal culture to identify fluoroquinolone-resistant organisms before transrectal prostate biopsy: do the culture results between office visit and biopsy correlate?

Michael A Liss et al.

Urology, 82(1), 67-71 (2013-06-29)

To investigate the performance of screening rectal cultures obtained 2 weeks before transrectal prostate biopsy to detect fluoroquinolone-resistant organisms and again at transrectal prostate biopsy. After institutional review board approval for observational study, we obtained a rectal culture on patients

Automated HPLC assay of fluoxetine and norfluoxetine in serum.

J H Nichols et al.

Clinical chemistry, 40(7 Pt 1), 1312-1316 (1994-07-01)

This automated assay determines the concentration of the antidepressant fluoxetine (Prozac) and its active metabolite norfluoxetine in serum by reversed-phase HPLC with spectrophotometric detection. Extraction, injection, and quantification are performed by the Gilson Aspec automated sample handler. The patient's specimen

A unique spectrum of somatic PIK3CA (p110alpha) mutations within primary endometrial carcinomas.

Meghan L Rudd et al.

Clinical cancer research : an official journal of the American Association for Cancer Research, 17(6), 1331-1340 (2011-01-27)

The goal of this study was to comprehensively define the incidence of mutations in all exons of PIK3CA in both endometrioid endometrial cancer (EEC) and nonendometrioid endometrial cancer (NEEC). We resequenced all coding exons of PIK3CA and PTEN, and exons

Reduced delayed rectifier K+ current, altered electrophysiology, and increased ventricular vulnerability in MLP-deficient mice.

Ajmal Gardiwal et al.

Journal of cardiac failure, 13(8), 687-693 (2007-10-10)

Mice with a knockout (KO) of muscle LIM protein (MLP) exhibit many morphologic and clinical features of human cardiomyopathy. In humans, MLP-expression is downregulated both in ischemic and dilative cardiomyopathy. In this study, we investigated the effects of MLP on

[The G894T mutation of the endothelial nitric oxide synthase gene is associated with coronary atherosclerotic heart disease in Chinese].

Danhong Wei et al.

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics, 19(6), 471-474 (2002-12-12)

To investigate the association of the endothelial nitric oxide synthase (eNOS) gene polymorphism with coronary atherosclerotic heart disease (CHD) in Chinese Han nationality. For 106 patients with CHD and 108 unrelated health individuals, the G894T mutation at exon 7 of

Low-Volume Lymph Node Metastases in Endometrial Carcinoma.

Lani K Clinton et al.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 27(6), 1165-1170 (2017-06-13)

The aim of this study was to determine the histopathologic characteristics of patients with endometrial carcinoma with low-volume metastases (micrometastases and isolated tumor cells) compared with macrometastases. We performed a retrospective review of patients with endometrial carcinoma. Among 350 robotic-assisted

FDG uptake observed around the lumbar spinous process: relevance to Baastrup disease.

Kayo Nishimatsu et al.

Annals of nuclear medicine, 29(9), 766-771 (2015-07-15)

In positron emission tomography (PET) with F-18-fluorodeoxyglucose (FDG), non-tumorous focal uptake is often observed around the lumbar spinous processes (LSPs). Close approximation of LSPs with sclerosis is often seen, which is called Baastrup disease. The aim of this study was

Endurance training enhances BDNF release from the human brain.

Thomas Seifert et al.

American journal of physiology. Regulatory, integrative and comparative physiology, 298(2), R372-R377 (2009-11-20)

The circulating level of brain-derived neurotrophic factor (BDNF) is reduced in patients with major depression and type-2 diabetes. Because acute exercise increases BDNF production in the hippocampus and cerebral cortex, we hypothesized that endurance training would enhance the release of

Characterization of Shiga toxin-producing Escherichia coli O26 strains and establishment of selective isolation media for these strains.

Reiji Hiramatsu et al.

Journal of clinical microbiology, 40(3), 922-925 (2002-03-07)

We characterized the carbohydrate-fermenting ability of 31 strains of Shiga toxin-producing Escherichia coli (STEC) O26 isolated from diarrhea patients in Aichi Prefecture, Japan, in order to establish selective isolation media for these strains. None of the 31 STEC O26 strains

In vivo study of histamine H4 receptor in immunomodulation.

T Tripathi et al.

Bratislavske lekarske listy, 113(11), 641-647 (2012-11-10)

Recently accumulating evidence has highlighted the role of histamine in inflammation and immune reaction by histamine H4-receptor, however the role of histamine via H4-receptor in immunomodulation is still unclear. Therefore, the present study was designed to study the immunomodulatory role

[The association between polymorphism of the serotonin 2A, 2C receptor genes and obstructive sleep apnea-hypopnea syndrome in Han population].

Jian-Yong Zhu et al.

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 30(12), 912-917 (2008-03-14)

To investigate the association between polymorphisms of the serotonin 2A, 2C receptor genes and obstructive sleep apnea-hypopnea syndrome (OSAHS), and therefore to explore the genotypes related to OSAHS. The T102C and A1438G polymorphisms of the serotonin 2A receptor genes and

Inhibition of CaMKII Attenuates Progressing Disruption of Ca(2+) Homeostasis Upon Left Ventricular Assist Device Implantation in Human Heart Failure.

Thomas H Fischer et al.

Artificial organs, 40(8), 719-726 (2016-01-28)

In heart failure, left ventricular assist device (LVAD) implantation is performed to ensure sufficient cardiac output. Whereas some patients are subsequently weaned from LVAD support, other patients still need heart transplantation. To elucidate underlying mechanisms, we assessed the arrhythmogenic SR-Ca(2+)

Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial.

Benjamin Speich et al.

The Lancet. Infectious diseases, 15(3), 277-284 (2015-01-16)

Existing anthelmintic drugs (eg, albendazole and mebendazole) have low efficacy against the intestinal nematode species Trichuris trichiura and the drug pipeline is exhausted. We aimed to investigate the strategy of combination chemotherapy with existing drugs to establish whether their efficacy

Neoadjuvant carboplatin in patients with triple-negative and HER2-positive early breast cancer (GeparSixto; GBG 66): a randomised phase 2 trial.

Gunter von Minckwitz et al.

The Lancet. Oncology, 15(7), 747-756 (2014-05-06)

Preclinical data suggest that triple-negative breast cancers are sensitive to interstrand crosslinking agents, and that synergy may exist for the combination of a taxane, trastuzumab, and a platinum salt for HER2-positive breast cancer. We therefore aimed to assess the efficacy

[Role of endothelial progenitor cells in optic nerve injury of rats].

Yu-mei Liu et al.

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 47(12), 1089-1095 (2012-02-18)

To investigate the role of endothelial progenitor cells (EPC) in the injury of rat optic nerve. An experimental study. The rat model of optic nerve injury was created by fluid percussion brain injury device (FPI). On hundred and eight rats

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