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关键词:'137-16-6'
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C M Branch et al.
Journal of steroid biochemistry, 16(2), 345-347 (1982-02-01)
The concentrations of estrone-3-glucuronide (E1-3-G), estradiol-17 beta-glucuronide (E2-17 beta-G), estriol-16 alpha-glucuronide (E3-16 alpha-G) and LH/hCG have been measured in daily samples of early morning urine from six women who conceived during the period study. The specimens were collected from the
Daniel J Lovell et al.
Arthritis & rheumatology (Hoboken, N.J.), 70(9), 1508-1518 (2018-04-01)
To determine the frequency, time to flare, and predictors of disease flare upon withdrawal of anti-tumor necrosis factor (anti-TNF) therapy in children with polyarticular forms of juvenile idiopathic arthritis (JIA) who demonstrated ≥6 months of continuous clinically inactive disease. In
Azubuike I Okemefuna et al.
The Journal of biological chemistry, 285(2), 1053-1065 (2009-10-24)
Factor H (FH) regulates the activation of C3b in the alternative complement pathway, both in serum and at host cell surfaces. It is composed of 20 short complement regulator (SCR) domains. The Y402H polymorphism in FH is a risk factor
A Benshushan et al.
Fertility and sterility, 59(5), 1065-1069 (1993-05-01)
To examine the effect of GnRH analogue (GnRH-a) on the quality of frozen-thawed embryos and the pregnancy rate (PR) resulting from transfer. A retrospective study of two groups of women undergoing transfers of frozen-thawed embryos. In group 1 ovulation induction
Paolo Peterlongo et al.
Carcinogenesis, 27(11), 2243-2249 (2006-06-16)
The genetic factors that cause clustering of colorectal cancers (CRCs) other than mutations in the mismatch repair (MMR) genes are not well understood. Clustering in families who lack MMR gene mutations may be attributable to low-penetrance mutations. Hypothetically, mono-allelic MYH
Theresa Engels et al.
Hypertension in pregnancy, 32(4), 459-473 (2013-08-21)
The utility of angiogenic and antiangiogenic biomarkers as diagnostic tools in preeclampsia (PE) has been shown in previous studies. Our study's aim was to evaluate the use of automated measurement of sFlt1, PlGF and their ratio (sFlt1/PlGF) in differential diagnosis
Swathi Kaliki et al.
Ophthalmology, 122(6), 1165-1172 (2015-04-07)
To identify the clinical features predictive of high-risk retinoblastoma on histopathology. Case-control study. A total of 145 cases with histopathologic high-risk features of retinoblastoma and 258 controls without high-risk features. Enucleation and adjuvant chemotherapy. High-risk features on histopathology were defined
Heikki Tuominen et al.
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 27(1), 109-117 (2018-05-04)
In up to 65% of cardiac sarcoidosis patients, the disease is confined to the heart. Diagnosing isolated cardiac sarcoidosis is challenging due to the low sensitivity of endomyocardial biopsy. If cardiac sarcoidosis is part of biopsy-confirmed systemic sarcoidosis, the diagnosis
Tetsuo Kobayashi et al.
Journal of periodontology, 80(5), 792-799 (2009-05-02)
Cytokines play a major role in the pathogenesis of rheumatoid arthritis (RA) and periodontitis. Both diseases were previously shown to be partly influenced by cytokine gene polymorphisms. Therefore, we evaluated whether the distributions of the cytokine genotypes were unique to
S Roncella et al.
Journal of experimental & clinical cancer research : CR, 24(2), 265-271 (2005-08-23)
Occult carcinoma cells in peripheral blood of breast cancer (BC) patients is generally associated with poor disease prognosis. Reverse transcriptase-polymerase chain reaction (RT-PCR) is a sensitive method for revealing rare circulating cancer cells. The target mRNA must be carefully chosen
H Weston et al.
Internal medicine journal, 41(5), 408-415 (2010-08-05)
Thrombotic events in essential thrombocythaemia (ET) are difficult to predict with current risk stratification based on age and prior history of thrombosis. We aimed to assess the predictive value of the JAK2 V617F mutation (JAK2) and spontaneous erythroid colony (SEC)
Xiaodong Zhou et al.
Arthritis and rheumatism, 60(12), 3807-3814 (2009-12-02)
To identify systemic sclerosis (SSc) susceptibility loci via a genome-wide association study. A genome-wide association study was performed in 137 patients with SSc and 564 controls from Korea using the Affymetrix Human SNP Array 5.0. After fine-mapping studies, the results
Bolesław Rutkowski et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 39(4), 335-343 (2019-05-28)
Background:Residual renal function (RRF) affects sodium and fluid balance. The aim of this analysis was to examine the impact of RRF on the effect of a sodium-reduced peritoneal dialysis fluid (PDF) on blood pressure (BP).Methods:This is a post-hoc analysis of
H S Kang et al.
American journal of physiology. Renal physiology, 281(6), F1141-F1147 (2001-11-13)
tk;1Adenosine plays a role in the control of water and electrolyte reabsorption in the distal tubule. As the distal convoluted tubule is important in the regulation of renal Mg(2+) balance, we determined the effects of adenosine on cellular Mg(2+) uptake
Benjamin Brokinkel et al.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 21(12), 2077-2082 (2014-07-30)
During treatment of large vestibular schwannomas, incomplete resection (IR) followed by Gamma Knife surgery (GKS; Elekta AB, Stockholm, Sweden) possibly offers tumor growth control and good clinical outcome, and is being discussed as an alternative to complete tumor removal with
I M Modlin et al.
Regulatory peptides, 1(4), 279-288 (1981-01-01)
Four dogs with chronic gastric fistulas were give intravenous bombesin nonapeptide (B9), ranatensin, and litorin by constant infusion for 90 min at 1.2 micrograms x kg-1 on separate days. A dose response study with substance P (1.5, 3.0, 60, 18
Simone Helmig et al.
International journal of molecular medicine, 26(1), 143-149 (2010-06-02)
Cytochrome P450 2E1 (CYP2E1), a phase I enzyme, is involved in the activation of a broad spectrum of pro-carcinogens. The importance of this enzyme for pharmacology is derived from its unique substrate spectrum. Large inter-individual differences in the toxicity of
M Miettinen et al.
Human pathology, 31(9), 1062-1067 (2000-10-03)
Vascular endothelial cells are specialized mesenchyme-derived epithelial-like lining cells which are the essential participants in benign and malignant vascular tumors. Although endothelia in lower animals often express keratins (K), human endothelia are generally K negative and vimentin-positive. However, K expression
B Kögel et al.
Arzneimittel-Forschung, 49(8), 679-684 (1999-09-14)
The inotropic efficacy, arrhythmogenicity and cardiohaemodynamic properties of AL 107 (3-alpha-methyl-digitoxigenin glucoside, CAS 62190-59-4), a novel cardiac glycoside, were studied in anaesthetized dogs with pentobarbital-induced acute cardiac insufficiency. Three groups of dogs received AL 107, ouabain or verhicle. The cardiac
Dirk Weismann et al.
Clinical endocrinology, 82(2), 188-196 (2014-07-22)
In patients with a relapse-free history of phaeochromocytoma/paraganglioma (PCC/PGL), persistent hypertension has been reported, but has not been well characterized. In 28 patients [mean age 54·5 (26-81) years] with a relapse-free history of PCC/PGLs, we prospectively analysed resting, supine blood
Robert Jablonowski et al.
Radiology, 274(2), 370-378 (2014-09-24)
To provide proof of concept that expansion of myocardial extracellular volume (MECV), measured at contrast material-enhanced multidetector computed tomography (CT), can be used as a (a) marker for viability based on histologic confirmation and (b) predictor of severity of myocardial
S Mohan et al.
Bone, 41(5), 860-868 (2007-09-22)
Phenotype-driven mutagenesis approach in the mouse holds much promise as a method for revealing gene function. Earlier, we have described an N-ethyl-N-nitrosourea (ENU) mutagenesis screen to create genome-wide dominant mutations in the mouse model. Using this approach, we describe identification
A Cristina Rossi et al.
European journal of obstetrics, gynecology, and reproductive biology, 158(1), 9-16 (2011-06-07)
The aim of this study is to review literature about the efficacy of low dose aspirin (LDA) and vitamins C/E (VCE) to prevent pre-eclampsia in women at high and low risk. Randomized clinical trials were included and stratified for high
Fred Saad et al.
The Lancet. Oncology, 16(3), 338-348 (2015-02-24)
Orteronel is an investigational, partially selective inhibitor of CYP 17,20-lyase in the androgen signalling pathway, a validated therapeutic target for metastatic castration-resistant prostate cancer. We assessed orteronel in chemotherapy-naive patients with metastatic castration-resistant prostate cancer. In this phase 3, double-blind
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