CN
184861
应用筛选条件
关键词:'184861'
显示 1-30 共 374 条结果 关于 "184861" 范围 论文
Zhi Xiong Chong et al.
Archives of biochemistry and biophysics, 695, 108583-108583 (2020-09-22)
miRNAs are short non-coding RNA molecules that regulate the expression of mRNA post-transcriptionally. MiRNAs that are secreted into the circulation, also termed circulating miRNAs, have been studied extensively for their roles in diagnosis, treatment and prognosis of human breast cancer.
Parker M Pennington et al.
Journal of equine veterinary science, 88, 102938-102938 (2020-04-19)
Insulin resistance (IR) is characterized by an increase in biomarkers of systemic inflammation and susceptibility to laminitis in horses. Impacts on reproduction include a lengthened interovulatory period in horses. Dietary omega-3 (docosahexaenoic acid [DHA]) promotes anti-inflammatory processes, has been implicated
Iwona Jarocka-Karpowicz et al.
Molecules (Basel, Switzerland), 25(8) (2020-04-25)
Subarachnoid hemorrhage (SAH) accounts for 3% of all strokes. As more and more data indicates the role of oxidative stress in acute brain damage caused by SAH, an attempt was made to correlate the clinical status of patients with systemic
Anushobha Regmi et al.
Plant physiology, 184(2), 720-737 (2020-08-01)
Seed triacylglycerol (TAG) biosynthesis involves a metabolic network containing multiple different diacylglycerol (DAG) and acyl donor substrate pools. This network of pathways overlaps with those for essential membrane lipid synthesis and utilizes multiple different classes of TAG biosynthetic enzymes. Acyl
Marieta Georgieva et al.
Pain, 160(12), 2724-2742 (2019-08-01)
About half of patients with spinal cord injury (SCI) develop debilitating central neuropathic pain (CNP), with no effective treatments. Thus, effective, safe, and novel therapies are needed urgently. Previously, docosahexaenoic acid (DHA) was reported to confer neuroprotection in preclinical SCI
Parisa Ghaffari-Makhmalbaf et al.
Life sciences, 264, 118719-118719 (2020-11-08)
As a natural compound, docosahexaenoic acid (DHA) exerts anti-cancer and anti-angiogenesis functions through exosomes; however, little is known about the molecular mechanisms. Breast cancer (BC) cells were treated with DHA (50 μM) and then tumor cell-derived exosomes (TDEs) were collected and
Koji Karasawa et al.
Chemical & pharmaceutical bulletin, 68(8), 762-765 (2020-08-04)
The excellent antibacterial activity of manuka honey has been well-documented and is often evaluated according to the unique manuka factor (UMF) index. UMF is determined by an assay based on a bacterial culture, which is time-consuming and does not allow
Ke Chen et al.
Apoptosis : an international journal on programmed cell death, 25(3-4), 192-204 (2020-01-03)
Artemisinin (ART) and dihydroartemisinin (DHA) are first-line antimalarial drugs and have been reported to have anti-obesity effects. Hyperlipidemia is associated with β-cell damage in obese subjects, which could contribute to the pathogenesis of type 2 diabetes. In addition to their
Structural chemistry and guest inclusion of a new supramolecular material showing sensitivity to organic solvent vapors.
Meinhold D, et al.
Advanced Materials, 9(12), 958-961 (1997)
M Chataigner et al.
Brain, behavior, and immunity, 91, 716-730 (2020-09-26)
Brain aging is characterized by a decline in cognitive functions, which can lead to the development of neurodegenerative pathologies. Age-related spatial learning and memory deficits are associated with a chronic low-grade inflammation. Anxiety disorders and stress response alterations, occurring for
Michele Mietus-Snyder et al.
PloS one, 15(10), e0240437-e0240437 (2020-10-21)
Poor diets contribute to metabolic complications of obesity, insulin resistance and dyslipidemia. Metabolomic biomarkers may serve as early nutrition-sensitive health indicators. This family-based lifestyle change program compared metabolic outcomes in an intervention group (INT) that consumed 2 nutrient bars daily
Wenju Xu et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 240, 110373-110373 (2019-11-05)
The Japanese eel Anguilla japonica is a catadromous fish species with considerable farming scale. Previous studies showed that dietary α-linolenic acid (18:3n-3) and linoleic acid (18:2n-6) satisfied essential fatty acid requirements in eel, which suggested that Japanese eel should have
Samuel C R Sherratt et al.
Biochimica et biophysica acta. Biomembranes, 1862(7), 183254-183254 (2020-03-07)
Oxidation of small dense low-density lipoprotein (sdLDL) and membranes is causally related to atherosclerosis. The omega-3 fatty acid (FA) eicosapentaenoic acid (EPA, 20:5, ω-3) significantly reduced oxidized LDL in patients with hypertriglyceridemia by unknown mechanisms. We compared EPA effects to
Claudia Delgadillo-Puga et al.
Animals : an open access journal from MDPI, 9(8) (2019-08-04)
Research efforts have focused on the evaluation of the bioactive quality of animal products (milk, cheese, meat, and other by-products) contrasting various feeding strategies coming from different ecological zones. The study aimed to describe the fatty acids (FA), polyphenols (P)
Mardia Guadalupe López-Alarcón et al.
Journal of pediatric endocrinology & metabolism : JPEM, 33(3), 347-354 (2020-02-19)
Introduction Hyperandrogenism (HA), either clinical or biochemical, is associated with obesity in adolescent girls. Long chain polyunsaturated fatty acids ω3 (LCPUFA-ω3) play protective roles in some obesity-associated morbidities, but their contribution to preventing HA is unclear. Our aim was to
Isabella C Arellanes et al.
EBioMedicine, 59, 102883-102883 (2020-07-22)
Past clinical trials of docosahexaenoic Acid (DHA) supplements for the prevention of Alzheimer's disease (AD) dementia have used lower doses and have been largely negative. We hypothesized that larger doses of DHA are needed for adequate brain bioavailability and that
R Akbari Moghaddam Kakhki et al.
Poultry science, 99(4), 2087-2099 (2020-04-04)
Impact of feeding n-3 fatty acids (FA) to ISA brown and Shaver white breeders and their progeny on bone development in pullets was investigated. Breeders were fed Control (CON); CON + 1% microalgae (DMA: Aurantiochytrium limacinum) as the source of docosahexaenoic acid;
Manuel Saenz de Viteri et al.
Antioxidants (Basel, Switzerland), 9(9) (2020-09-10)
Retinal pigment epithelium (RPE) is a key regulator of retinal function and is directly related to the transport, delivery, and metabolism of long-chain n-3 polyunsaturated fatty acids (n3-PUFA), in the retina. Due to their functions and location, RPE cells are
Naoya Kataoka et al.
Applied microbiology and biotechnology, 105(3), 1227-1236 (2021-01-22)
Dihydroxyacetone (DHA), a chemical suntan agent, is produced by the regiospecific oxidation of glycerol with Gluconobacter thailandicus NBRC3255. However, this microorganism consumes DHA produced in the culture medium. Here, we attempted to understand the pathway for DHA metabolism in NBRC3255
Jae-Won Choi et al.
Nutrients, 11(9) (2019-09-11)
Omega-3 polyunsaturated fatty acids (ω3-PUFAs) have potential protective activity in a variety of infectious diseases, but their actions and underlying mechanisms in Toxoplasma gondii infection remain poorly understood. Here, we report that docosahexaenoic acid (DHA) robustly induced autophagy in murine
Chunying Hou et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 126, 109862-109862 (2020-03-03)
Hepatocellular carcinoma (HCC), as the major primary liver cancer, is one of the most prevalent malignant diseases with a high mortality rate worldwide. Prior studies have demonstrated that dihydroartemisinin (DHA), the semisynthetic derivative of artemisinin, possesses anti-HCC activity. The multikinase
Qiong Xiao et al.
International journal of biological macromolecules, 163, 2314-2324 (2020-09-25)
Agarose is a potential wall material for encapsulation owing to its high oxygen barrier, but its high hydrophilia and low emulsifying activity restrict its application as a wall material for hydrophobic actives. The aim of this study was to evaluate
Jong-Jae Yi et al.
Biochemical and biophysical research communications, 533(4), 893-898 (2020-10-04)
Lipoxygenases (LOXs) are implicated in the biosynthesis of pro- and anti-inflammatory lipid mediators involved in immune cell signaling, most of which catalyze peroxidation of polyunsaturated fatty acids by distinct regio- and stereoselectivity. Current reports suggested that conserved amino acid, Gly
Muhammad Usman Jamil et al.
Archives of biochemistry and biophysics, 679, 108156-108156 (2019-10-21)
Recently, growing attention has been given to new classes of bioactive lipid mediators derived from ω-3 polyunsaturated fatty acids, such as docosahexaenoic acid (DHA), especially in the context of their role as endogenous signal modulators. One such molecule is 17-oxo-DHA
T Higuchi et al.
Human & experimental toxicology, 39(4), 500-513 (2019-12-27)
Methotrexate (MTX)-induced intestinal mucosal injury in animals has been studied to understand how MTX can cause gastrointestinal disorders, but the pathogenesis of gastrointestinal disorders is still uncertain. We have attempted to reveal how dietary factors influence intestinal toxicity due to
Cai-Xia Lei et al.
Comparative biochemistry and physiology. Part D, Genomics & proteomics, 33, 100633-100633 (2019-11-17)
Promoting highly unsaturated fatty acid (HUFA) uptake and deposition can improve nutritional value of farmed fish and reduce dietary fish oil addition. Previously, we found that the golden pompano Trachinotus ovatus liver HUFA content increased with the increasing of dietary
Aamir Salam Teeli et al.
Animal reproduction science, 211, 106230-106230 (2019-12-02)
Dietary n-3 polyunsaturated fatty acids (n-3 PUFA) improve utero-ovarian functions and embryonic survival in postpartum dairy cows. Because early embryonic mortality is the major cause of repeat breeding (RB) in cows, there was investigation of the effect of dietary supplementation
Walaa Darwiche et al.
Journal of experimental & clinical cancer research : CR, 39(1), 228-228 (2020-10-30)
Novel, less toxic, cost-effective and safe therapeutic strategies are needed to improve treatment of chronic lymphocytic leukemia (CLL). Ascorbic acid (AA, vitamin C) has shown a potential anti-cancer therapeutic activity in several cancers. However, the anti-cancer effects of ascorbic acid
Zhonghao Jiang et al.
Nature, 572(7769), 341-346 (2019-08-02)
Salinity is detrimental to plant growth, crop production and food security worldwide. Excess salt triggers increases in cytosolic Ca2+ concentration, which activate Ca2+-binding proteins and upregulate the Na+/H+ antiporter in order to remove Na+. Salt-induced increases in Ca2+ have long
Shengdi Guo et al.
Frontiers in pharmacology, 11, 226-226 (2020-03-27)
Recently, chemodynamic therapy (CDT) has represented a new approach for cancer treatment with low toxicity and side effects. Nonetheless, it has been a challenge to improve the therapeutic effect through increasing the amount of reactive oxygen species (ROS). Herein, we
1/13