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Christina M Birch et al.
Scientific reports, 5, 11347-11347 (2015-07-02)
Plasmodium falciparum malaria parasites invade and remodel human red blood cells (RBCs) by trafficking parasite-synthesized proteins to the RBC surface. While these proteins mediate interactions with host cells that contribute to disease pathogenesis, the infected RBC surface proteome remains poorly
Reza Sohrabi et al.
The Plant cell, 27(3), 874-890 (2015-03-01)
Plant-derived volatile compounds such as terpenes exhibit substantial structural variation and serve multiple ecological functions. Despite their structural diversity, volatile terpenes are generally produced from a small number of core 5- to 20-carbon intermediates. Here, we present unexpected plasticity in
Fangchao Yin et al.
Lab on a chip, 21(3), 571-581 (2020-12-16)
The poor predictive power of existing preclinical models has spurred efforts to develop human-relevant models for accurate assessment of drug safety. In this work, we developed a multi-organoids-on-a-chip system derived from human induced pluripotent stem cells (hiPSCs), which allows for
Hao Lu et al.
Applied biochemistry and biotechnology, 177(1), 105-117 (2015-07-15)
The objective of this study was to understand glucose synthesis of a protein-based artificial photosynthesis system affected by operating conditions, including the concentrations of reactants, reaction temperature, and illumination. Results from non-vesicle-based glyceraldehyde-3-phosphate (GAP) and glucose synthesis showed that the
Yuanyuan Cao et al.
Advanced materials (Deerfield Beach, Fla.), 31(21), e1808186-e1808186 (2019-04-09)
Pressure-responsive chiral photonic aerogels are fabricated by combining liquid crystal self-assembly and ice-templating processes. The aerogels have a hierarchical structure in which the primary 2D chiral nematic structured walls of cellulose nanocrystals form ribbons that support a secondary 3D cellular
Hian Hian See et al.
SLAS technology, 23(1), 70-82 (2017-09-19)
Mechanical properties of the extracellular matrix (ECM) have been observed to influence the behavior of cells. Investigations on such an influence commonly rely on using soluble cues to alter the global intrinsic ECM properties in order to study the subsequent
Xiaolin Wang et al.
Lab on a chip, 16(2), 282-290 (2015-12-01)
This paper reports a method for generating an intact and perfusable microvascular network that connects to microfluidic channels without appreciable leakage. This platform incorporates different stages of vascular development including vasculogenesis, endothelial cell (EC) lining, sprouting angiogenesis, and anastomosis in
Anchalee Prasansuklab et al.
BMC complementary and alternative medicine, 18(1), 223-223 (2018-07-26)
Streblus asper is a well-known plant native to Southeast Asia. Different parts of the plant have been traditionally used for various medicinal purposes. However, there is very little scientific evidence reporting its therapeutic benefits for potential treatment of Alzheimer's disease
Xiaoning Yuan et al.
Arthritis & rheumatology (Hoboken, N.J.), 67(1), 182-192 (2014-10-14)
To study the interactions between vascular endothelial cells and meniscal fibrochondrocytes from the inner avascular and outer vascular regions of the meniscus and to identify angiogenic factors that enhance cell migration and integrative repair. Bovine meniscal fibrochondrocytes (bMFCs) from the
Ibolya E Kepiro et al.
ACS nano, 14(2), 1609-1622 (2019-12-04)
Antimicrobial resistance stimulates the search for antimicrobial forms that may be less subject to acquired resistance. Here we report a conceptual design of protein pseudocapsids exhibiting a broad spectrum of antimicrobial activities. Unlike conventional antibiotics, these agents are effective against
Cemile Kilic Bektas et al.
Biomaterials science, 8(1), 438-449 (2019-11-21)
Tissue engineering aims to replace missing or damaged tissues and restore their functions. Three-dimensional (3D) printing has been gaining more attention because it enables the researchers to design and produce cell loaded constructs with predetermined shapes, sizes, and interior architecture.
Reinhard Depping et al.
OncoTargets and therapy, 12, 8387-8399 (2019-10-22)
The nucleocytoplasmic transport of macromolecules is critical for both cell physiology and pathophysiology. Exportin 1 (XPO1), the major nuclear export receptor, is involved in the cellular adaptation to reduced oxygen availability by controlling the nuclear activity of the hypoxia-inducible factors
Rui Guo et al.
The Analyst, 145(10), 3569-3574 (2020-05-01)
CRISPR/Cas9 has become a powerful tool for genomic manipulation, and the evaluation of the Cas9 activity is essential for the precise control of the CRISPR system. Herein, we develop a point-of-care platform for the rapid and visible determination of the
Depeng Liu et al.
Materials science & engineering. C, Materials for biological applications, 90, 180-188 (2018-06-02)
Dissolving microneedles (MNs) display high efficiency, safety and painless in transdermal delivery for poorly permeable drugs. Here, a dissolving composite MNs prepared from insulin-loaded CaCO3 microparticles (INS-CaCO3 MPs) and poly(vinyl pyrrolidone) (PVP) as matrix were fabricated with two-step centrifuging and
Dong Wook Lee et al.
Biotechnology progress, 35(1), e2701-e2701 (2018-10-09)
Perfusion flow is one of the essential elements and advantages of organ-on-a-chip technology. For example, microfluidics have enabled implementation of perfusion flow and recapitulation of fluidic environment for vascular endothelial cells. The most prevalent method of implementing flow in a
Haig A Eskandarian et al.
Nature microbiology, 2, 17094-17094 (2017-06-27)
Cell division is tightly controlled in space and time to maintain cell size and ploidy within narrow bounds. In bacteria, the canonical Minicell (Min) and nucleoid occlusion (Noc) systems together ensure that division is restricted to midcell after completion of
Nandini Bhandaru et al.
Soft matter, 13(27), 4709-4719 (2017-06-15)
Substrate pattern guided self-organization of ultrathin and confined polymeric films on a topographically patterned substrate is a useful approach for obtaining ordered meso and nano structures over large areas, particularly if the ordering is achieved during film preparation itself, eliminating
Nakarin Suwannarach et al.
International journal of food microbiology, 244, 52-61 (2017-01-10)
The presence of microorganisms on the eggshell surface is a factor of consideration in determining egg quality. These microorganisms can contribute to egg spoilage and can infect the egg. In this study, 18 morphotypes of microorganisms were isolated from eggshells.
Jin-Xuan Cao et al.
Food chemistry, 240, 346-353 (2017-09-28)
To investigate the influence of oxidative modifications of G-actin on its binding ability with aroma compounds, the influence of H
Lucia Valverde-Som et al.
Journal of the science of food and agriculture, 98(11), 4245-4252 (2018-02-10)
The organoleptic quality of virgin olive oil depends on positive and negative sensory attributes. These attributes are related to volatile organic compounds and phenolic compounds that represent the aroma and taste (flavour) of the virgin olive oil. The flavour is
Zhaogang Yang et al.
Nature biomedical engineering, 4(1), 69-83 (2019-12-18)
Exosomes are attractive as nucleic-acid carriers because of their favourable pharmacokinetic and immunological properties and their ability to penetrate physiological barriers that are impermeable to synthetic drug-delivery vehicles. However, inserting exogenous nucleic acids, especially large messenger RNAs, into cell-secreted exosomes
Kiran Raj M et al.
Biomicrofluidics, 13(1), 014103-014103 (2019-03-15)
We bring out unique aspects of the pulsatile flow of a blood analog fluid (Xanthan gum solution) in a biomimetic microfluidic channel. Pressure waveforms that mimic biologically consistent pulsations are applied on physiologically relevant cylindrical microchannels fabricated using polydimethylsiloxane. The
Vasiliki Gkarane et al.
Foods (Basel, Switzerland), 9(9) (2020-09-10)
The aim of this study was to investigate the differences in the volatile profile of meat from chickens fed with alternative protein diets (such as algae or insect) through two different trials. In Trial 1, broiler chicken at one day
Lourdes Jachero et al.
Environmental science and pollution research international, 24(32), 25092-25102 (2017-09-19)
The bioavailability of polychlorinated biphenyls (PCBs) in soils amended with biosolids was estimated using an aqueous leaching process of the compounds combined with rotating disk sorptive extraction (RDSE), and compared with bioavailability determined through of PCB absorption in wheat plants
Natalia A Wojas et al.
Journal of colloid and interface science, 541, 42-55 (2019-01-27)
Understanding the complex and dynamic nature of calcite surfaces under ambient conditions is important for optimizing industrial applications. It is essential to identify processes, their reversibility, and the relevant properties of CaCO3 solid-liquid and solid-gas interfaces under different environmental conditions
Samantha K Schmitt et al.
Advanced healthcare materials, 4(10), 1555-1564 (2015-05-23)
Human mesenchymal stem cells (hMSCs) are a widely available and clinically relevant cell type with a host of applications in regenerative medicine. Current clinical expansion methods can lead to selective changes in hMSC phenotype potentially resulting from relatively undefined cell
Nandini Debnath et al.
Scientific reports, 9(1), 10587-10587 (2019-07-25)
The work investigates fouling in a microfluidic membrane mimic (MMM) filtration system for foulants such as polystyrene particles and large polymeric molecules. Our MMM device consists of a staggered arrangement of pillars which enables real-time visualization and analysis of pore-scale
Ivo Oliveira et al.
Journal of food science and technology, 56(8), 3764-3776 (2019-08-16)
In almonds, volatile compounds are major contributors to flavour, being scarce the current knowledge about their volatile profile. Hence, this work intended to characterize the volatile profile, using headspace solid-phase microextraction and gas chromatography-mass spectrometry, in raw and roasted almond
Nati Weinblum et al.
Frontiers in plant science, 12, 630155-630155 (2021-03-16)
The two-spotted spider mite (TSSM; Tetranychus urticae) is a ubiquitous polyphagous arthropod pest that has a major economic impact on the tomato (Solanum lycopersicum) industry. Tomato plants have evolved broad defense mechanisms regulated by the expression of defense genes, phytohormones
Microrheological characterization of covalent adaptable hydrogels for applications in oral delivery.
Nan Wu et al.
Soft matter, 15(29), 5921-5932 (2019-07-10)
The feasibility of a covalent adaptable hydrogel (CAH) as an oral delivery platform is explored using μ2rheology, microrheology in a microfluidic device. CAH degradation is initiated by physiologically relevant pHs, including incubation at a single pH and consecutively at different
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