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Daniel J T Kyle et al.
Biomaterials, 52, 88-102 (2015-03-31)
Reproducing extracellular matrix topographical cues, such as those present within acellular dermal matrix (ADM), in synthetic implant surfaces, may augment cellular responses, independent of surface chemistry. This could lead to enhanced implant integration and performance while reducing complications. In this
Qing Li et al.
Journal of biomechanics, 48(8), 1364-1370 (2015-03-31)
This study aimed to quantify the biomechanical properties of murine meniscus surface. Atomic force microscopy (AFM)-based nanoindentation was performed on the central region, proximal side of menisci from 6- to 24-week old male C57BL/6 mice using microspherical tips (Rtip≈5µm) in
A I S Neves et al.
Scientific reports, 5, 9866-9866 (2015-05-09)
Transparent and flexible electrodes are widely used on a variety of substrates such as plastics and glass. Yet, to date, transparent electrodes on a textile substrate have not been explored. The exceptional electrical, mechanical and optical properties of monolayer graphene
Mengmeng Cui et al.
Scientific reports, 5, 11616-11616 (2015-06-26)
Zoige wetland, locating on the Tibet Plateau, accounts for 6.2% of organic carbon storage in China. However, the fate of the organic carbon storage in the Zoige wetland remains poorly understood despite the Tibetan Plateau is very sensitive to global
Alice Cheng et al.
Biofabrication, 6(4), 045007-045007 (2014-10-08)
Additive manufacturing by laser sintering is able to produce high resolution metal constructs for orthopedic and dental implants. In this study, we used a human trabecular bone template to design and manufacture Ti-6Al-4V constructs with varying porosity via laser sintering.
Guobao Chen et al.
ACS applied materials & interfaces, 7(29), 15790-15802 (2015-07-08)
A growing body of evidence has shown that extracellular matrix (ECM) stiffness can modulate stem cell adhesion, proliferation, migration, differentiation, and signaling. Stem cells can feel and respond sensitively to the mechanical microenvironment of the ECM. However, most studies have
Iain P Hartley et al.
Global change biology, 21(10), 3712-3725 (2015-05-15)
Quantifying landscape-scale methane (CH4 ) fluxes from boreal and arctic regions, and determining how they are controlled, is critical for predicting the magnitude of any CH4 emission feedback to climate change. Furthermore, there remains uncertainty regarding the relative importance of
Paul Carini et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(25), 7767-7772 (2015-06-10)
Phytoplankton inhabiting oligotrophic ocean gyres actively reduce their phosphorus demand by replacing polar membrane phospholipids with those lacking phosphorus. Although the synthesis of nonphosphorus lipids is well documented in some heterotrophic bacterial lineages, phosphorus-free lipid synthesis in oligotrophic marine chemoheterotrophs
Alexander N Hristov et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(34), 10663-10668 (2015-08-01)
A quarter of all anthropogenic methane emissions in the United States are from enteric fermentation, primarily from ruminant livestock. This study was undertaken to test the effect of a methane inhibitor, 3-nitrooxypropanol (3NOP), on enteric methane emission in lactating Holstein
Weimin Sun et al.
Applied microbiology and biotechnology, 99(23), 10271-10282 (2015-08-08)
The shift of microbial communities during a transition from mesophilic anaerobic digestion (MAD) to thermophilic anaerobic digestion (TAD) was characterized in two treatments. One treatment was inoculated with sludge and the other was inoculated with manure. In this study, methane
Jessica L Terrell et al.
Nature communications, 6, 8500-8500 (2015-10-13)
Advances in nanotechnology have provided unprecedented physical means to sample molecular space. Living cells provide additional capability in that they identify molecules within complex environments and actuate function. We have merged cells with nanotechnology for an integrated molecular processing network.
Emil Bujak et al.
Investigational new drugs, 33(4), 791-800 (2015-05-20)
Phosphatidylserine (PS) and other anionic phospholipids, which become exposed on the surface of proliferating endothelial cells, tumor cells and certain leukocytes, have been used as targets for the development of clinical-stage biopharmaceuticals. One of these products (bavituximab) is currently being
Hiroshi Yoshitake et al.
PloS one, 10(7), e0133784-e0133784 (2015-07-30)
Ts4, an anti-sperm auto-monoclonal antibody, possesses immunoreactivity to the acrosomal region of mouse epididymal spermatozoa. In addition, the mAb shows specific immunoreactivity to reproduction-related regions such as testicular germ cells and early embryo. Our qualitative study previously showed that the
Isabel Wittenbrink et al.
Biomaterials, 62, 58-65 (2015-05-30)
Topographical features on the nanometer scale are known to influence cellular behavior. The response of specific cell types to various types of surface structures is currently still being investigated. Alumina ceramics play an important role as biomaterials, e.g., in medical
Kusum Mehla et al.
Omics : a journal of integrative biology, 19(7), 393-406 (2015-06-11)
Campylobacters are a major global health burden and a cause of food-borne diarrheal illness and economic loss worldwide. In developing countries, Campylobacter infections are frequent in children under age two and may be associated with mortality. In developed countries, they
Katrin Kittler et al.
Analytical and bioanalytical chemistry, 406(24), 5765-5774 (2014-07-30)
Cylindrospermopsin (CYN) is a cyanobacterial toxin associated with human and animal poisonings. Due to its toxicity in combination with its widespread occurrence, the development of reliable methods for selective, sensitive detection and accurate quantification is mandatory. Liquid chromatography tandem mass
Lian Bai et al.
Soft matter, 11(26), 5282-5293 (2015-06-09)
Bicontinuous, interfacially jammed, emulsion gels (bijels) are a novel class of materials composed of two immiscible phases with interpenetrating domains that are stabilized by a monolayer of colloidal particles at the interface. However, existing bijel systems so far all consist
Zuzana Urbanová et al.
FEMS microbiology ecology, 90(3), 633-646 (2014-09-10)
It is not well understood how the ecological status and microbial community composition of spruce swamp forests (SSF) relate to those found in bogs and fens. To clarify this, we investigated biogeochemical parameters and microbial community composition in a bog
Harumi Osago et al.
Analytical biochemistry, 467, 62-74 (2014-09-10)
We developed a method using liquid chromatography-electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) with a selected reaction monitoring (SRM) mode for simultaneous quantitative analysis of glycosaminoglycans (GAGs). Using one-shot analysis with our MS/MS method, we demonstrated the simultaneous quantification of a total
T Yin et al.
Journal of dairy science, 98(8), 5748-5762 (2015-06-01)
This study presents an approach combining phenotypes from novel traits, deterministic equations from cattle nutrition, and stochastic simulation techniques from animal breeding to generate test-day methane emissions (MEm) of dairy cows. Data included test-day production traits (milk yield, fat percentage
Sarah J Burke et al.
Organic & biomolecular chemistry, 13(9), 2726-2744 (2015-01-20)
Due to the profound extent to which natural products inspire medicinal chemists in drug discovery, there is demand for innovative syntheses of these often complex materials. This article describes the synthesis of tricarbocyclic natural product architectures through an extension of
O G Davies et al.
Journal of bone and mineral metabolism, 33(4), 371-382 (2014-07-07)
Stem-cell-based therapies provide a biological basis for the regeneration of mineralised tissues. Stem cells isolated from adipose tissue (ADSCs), bone marrow (BMSCs) and dental pulp (DPSCs) have the capacity to form mineralised tissue. However, studies comparing the capacity of ADSCs
Adrien Vigneron et al.
Applied and environmental microbiology, 81(10), 3451-3459 (2015-03-15)
In the Sonora Margin cold seep ecosystems (Gulf of California), sediments underlying microbial mats harbor high biogenic methane concentrations, fueling various microbial communities, such as abundant lineages of anaerobic methanotrophs (ANME). However, the biodiversity, distribution, and metabolism of the microorganisms
Yun-Jung Kim et al.
ChemSusChem, 8(15), 2496-2502 (2015-07-17)
The problem of high charge polarization is one of the most significant challenges in current nonaqueous Li-O2 batteries. The development of an electrode for the oxygen evolution reaction (OER) at reduced overpotential is thus essential. Here, we suggest a binder-free
Friederike S Rossmann et al.
PLoS pathogens, 11(2), e1004653-e1004653 (2015-02-24)
The microbiome and the phage meta-genome within the human gut are influenced by antibiotic treatments. Identifying a novel mechanism, here we demonstrate that bacteria use the universal communication molecule AI-2 to induce virulence genes and transfer them via phage release.
Ján Žabka et al.
European journal of mass spectrometry (Chichester, England), 20(3), 233-247 (2014-06-04)
2,2-Dinitroethene-1,1-diamine (FOX-7) was studied by means of electrospray ionization (ESI) and chemical ionization (CI) mass spectrometry in both positive and negative ion mode. Detailed mechanisms of unimolecular fragmentations of protonated and deprotonated FOX-7 were investigated using high- and low- energy
Xiaohu Dai et al.
Journal of hazardous materials, 297, 320-328 (2015-06-01)
In the present study, the feasibility of hygienic treatment and energy recovery of dead animals (pork as an experimental alternative) by high solid co-digestion with vinasse under mesophilic condition was investigated. A lab-scale digester was operated for 125 days with
A Romero-Perez et al.
Journal of animal science, 93(4), 1780-1791 (2015-05-29)
The objective was to evaluate whether long-term addition of 3-nitrooxypropanol (NOP) to a beef cattle diet results in a sustained reduction in enteric CH4 emissions in beef cattle. Eight ruminally cannulated heifers (637 ± 16.2 kg BW) were used in
Shaomei He et al.
mBio, 6(3), e00066-e00015 (2015-05-21)
Wetland restoration on peat islands previously drained for agriculture has potential to reverse land subsidence and sequester atmospheric carbon dioxide as peat accretes. However, the emission of methane could potentially offset the greenhouse gas benefits of captured carbon. As microbial
Yu Jia et al.
Environmental science and pollution research international, 22(13), 10047-10057 (2015-02-14)
To evaluate the potential suitability of digested sewage sludge (frequently termed biosolids) for use as underwater cover material for mine waste tailings, the degradability of biosolids at 20 - 22 °C under flooded anaerobic conditions was evaluated during incubation for 230 days.
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