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关键词:'73-31-4'
显示 1-30 共 74 条结果 关于 "73-31-4" 范围 论文
Gabriele Meroni et al.
Microorganisms, 7(12) (2020-01-01)
Staphylococcus pseudintermedius is a commensal bacterium frequently isolated from canine skin and recognized as a zoonotic agent especially for dog-owners. This study focused on (a) the antibiotic-resistance phenotypes; (b) the ability to produce biofilm (slime); and (c) the dissemination of
J Entwistle et al.
Gene, 163(2), 233-238 (1995-10-03)
We describe the isolation and characterization of the murine gene encoding RHAMM, a hyaluronan receptor which regulates focal adhesion turnover, is required for cell locomotion and is a critical downstream regulator of ras transformation. The RHAMM gene spans at least
Erwin Pauws et al.
Thyroid : official journal of the American Thyroid Association, 14(7), 500-505 (2004-08-17)
Serial analysis of gene expression (SAGE) was applied to compare expression profiles of normal thyroid tissue and papillary thyroid carcinoma (PTC). A SAGE tag corresponding to the partial cDNA for the small protein 31 (SMAP31) is upregulated approximately 13-fold in
P C Ho et al.
The pharmacogenomics journal, 3(6), 335-342 (2003-11-05)
The present study investigated the effect of cytochrome P450 2C9 (CYP2C9) genetic polymorphism on the biotransformation of valproic acid (VPA) to its hepatotoxic metabolite, 4-ene-VPA, and compared that to the formation of the inactive 4-OH-VPA and 5-OH-VPA. cDNA-expressed CYP2C9(*)2 and
Ali Dastranj Tabrizi et al.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists, 29(2), 99-107 (2010-02-23)
Primary ovarian mucinous carcinomas of the intestinal type are uncommon and earlier reports have included cases diagnosed according to older, less stringent, criteria (which would now be considered borderline tumors) and variable numbers of cases of metastatic adenocarcinoma. This study
T Doi et al.
Molecular and cellular biology, 7(2), 898-904 (1987-02-01)
A rat platelet factor 4 (PF4) cDNA has been isolated by immunoscreening a g lambda 11 rat megakaryocyte cDNA expression library. Sequence analysis of the rat PF4 cDNA revealed that this megakaryocyte protein is composed of a leader sequence of
Fang Huang et al.
Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 24(3), 179-182 (2006-11-11)
To test the in vitro effect of daphnetin on cytochrome C oxidase (COX) and ribonucleotide reductase (RNR) activity of Plasmodium falciparum. P. falciparum (FCC1/HN) was cultured in vitro using the method of Trager and Jensen. The effect of daphnetin and
Tuvia Hadar et al.
Pathology oncology research : POR, 11(1), 45-49 (2005-04-01)
The aim of this study was to investigate the expression of Ki-67, bcl-2 and p53 in parathyroid adenomas and their residual rim of normal parathyroid tissue. Specimens from 26 parathyroid adenomas were studied by immunohistochemical analysis for Ki-67, bcl-2 and
Rasmus Steen Pedersen et al.
Clinical and experimental pharmacology & physiology, 41(11), 870-878 (2014-08-15)
The aim of the present study was to determine the impact of CYP2C19*17 on the pharmacokinetics and pharmacodynamics of the active metabolite of clopidogrel and the pharmacokinetics of proguanil. Thus, we conducted an open-label two-phase cross-over study in 31 healthy
Fabien Durand et al.
Protein expression and purification, 88(1), 61-66 (2012-12-12)
A new laccase from the filamentous fungus Podospora anserina has been isolated and identified. The 73 kDa protein containing 4 coppers, truncated from its first 31 amino acids, was successfully overexpressed in Pichia pastoris and purified in one step with
H L Bonkovsky et al.
Hepatology (Baltimore, Md.), 27(6), 1661-1669 (1998-06-10)
In some, but not all countries, porphyria cutanea tarda (PCT) has been associated with chronic infection with the hepatitis C virus (HCV). Recently, PCT has also been associated with mutations in the HFE gene that are associated with HLA-linked hereditary
Alex Ward et al.
Neuroepidemiology, 38(1), 1-17 (2011-12-20)
Population allele frequencies of apolipoprotein E (APOE) vary by geographic region. The purpose of this study is to summarize and evaluate published estimates for the prevalence of APOE e4 carrier status among the population diagnosed with Alzheimer's disease (AD) by
Anatoly V Skalny et al.
Metabolic brain disease, 32(1), 195-202 (2016-09-02)
The objective of the study was to investigate hair trace elements content in children suffering from autism spectrum disorder (ASD). A total of 74 ASD children and 74 sex- and age-matched controls divided into two age groups (2-4 and 5-9 years)
Marita Gilljam et al.
Chest, 126(4), 1215-1224 (2004-10-16)
To define the clinical characteristics and diagnostic parameters of patients with cystic fibrosis (CF) diagnosed in adulthood. Retrospective cohort study. Tertiary care center. All patients with a diagnosis of CF made at the Toronto CF Clinics between 1960 and June
Shareef Muzyed et al.
International journal of biological macromolecules, 166, 789-797 (2020-11-07)
The ι-carrageenan degrading marine bacterium, Cellulophaga baltica, was isolated from the surface of a filamentous red alga Vertebrata fucoides. Maximum ι-carrageenase production was optimized by single-factor experiments. Optimal fermentation conditions were 1.6 g/L furcellaran, 4 g/L yeast extract as carbon sources, 5 g/L
Michiko Miyaki et al.
Oncology, 76(6), 430-434 (2009-05-08)
Cdc4 (Fbxw7) is a potential tumor suppressor that regulates ubiquitination and proteolysis of multiple targets such as cyclin E, c-Myc, c-Jun and Notch. CDC4 mutations were investigated in 194 colorectal carcinomas and adenomas for comparison between sporadic and hereditary cancers.
Kathryn M Gauthier et al.
American journal of physiology. Heart and circulatory physiology, 300(3), H725-H735 (2011-01-05)
Arachidonic acid (AA) metabolites function as EDHFs in arteries of many species. They mediate cyclooxygenase (COX)- and nitric oxide (NO)-independent relaxations to acetylcholine (ACh). However, the role of AA metabolites as relaxing factors in mouse arteries remains incompletely defined. ACh
Ruth Frikke-Schmidt et al.
JAMA, 299(21), 2524-2532 (2008-06-05)
Low levels of high-density lipoprotein (HDL) cholesterol are inversely related to cardiovascular risk. Whether this is a causal effect is unclear. To determine whether genetically reduced HDL cholesterol due to heterozygosity for 4 loss-of-function mutations in ABCA1 cause increased risk
J Cai et al.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 25(5), 630-630 (2018-08-05)
To investigate the faecal carriage of optrA-positive enterococci among asymptomatic healthy humans in Hangzhou, China, and to characterize the genetic context of optrA. A total of 3458 stool samples from healthy individuals were collected and cultured on a selective medium
C Labbé-Jullié et al.
Endocrinology, 131(4), 1999-2009 (1992-10-01)
To compare the structural topology of the human TSH to that of the structurally related gonadotropins, 10 peptides covering the entire primary sequence of the alpha- and beta-subunits of TSH were synthesized and used as antigens for the preparation of
Anders Karlsen et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(5), 6418-6436 (2020-03-14)
Blunted muscle hypertrophy and impaired regeneration with aging have been partly attributed to satellite cell (SC) dysfunction. However, true muscle regeneration has not yet been studied in elderly individuals. To investigate this, muscle injury was induced by 200 electrically stimulated
Antonio E Pontiroli et al.
Acta diabetologica, 56(2), 163-169 (2018-11-10)
Long-term comparisons between bariatric surgical techniques have been performed for gastric bypass (RYGB), sleeve gastrectomy (LSG), and biliopancreatic diversion (BPD) vs gastric banding (LAGB), but short-term studies (6 months-4 years) have only compared biliointestinal bypass (BIBP) and LAGB. The participating institutions regularly
Valtcho D Zheljazkov et al.
Journal of agricultural and food chemistry, 56(1), 241-245 (2007-12-13)
A field experiment was conducted to assess yield, oil content, and composition of 38 genotypes of sweet basil ( Ocimum basilicum L.). Overall, biomass yields were high and comparable to those reported in the literature. However, basil genotypes differed significantly
Yan Beauverd et al.
Platelets, 26(7), 632-637 (2014-10-03)
Thrombocytopenia is frequent in hospitalized patients, and heparin-induced thrombocytopenia (HIT) is often suspected when a decrease in platelet count is concomitant with heparin treatment. ELISA tests used for anti-PF4/heparin antibodies detection usually have high sensitivity but only fair specificity for
C Depatie et al.
Genomics, 66(2), 161-174 (2000-06-22)
The host-resistance locus Cmv1 controls viral replication of mouse cytomegalovirus (MCMV) in the spleen of infected mice. Cmv1 maps on distal chromosome 6, very tightly linked to the Ly49 gene family within a 0.35-cM interval defined proximally by Cd94/Nkg2d and
Nubia K Kaba et al.
American journal of physiology. Cell physiology, 295(5), C1454-C1463 (2008-10-03)
Ischemia-reperfusion injury is a common pathological occurrence causing tissue damage in heart attack and stroke. Entrapment of neutrophils in the vasculature during ischemic events has been implicated in this process. In this study, we examine the effects that lactacidosis and
Carole Ayoub Moubareck et al.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 84, 143-150 (2019-06-18)
Carbapenem resistance in Pseudomonas aeruginosa is growing and results from variable mechanisms. The objectives of the current study were to investigate mechanisms of carbapenem resistance and genetic relatedness of P. aeruginosa isolates recovered in Dubai hospitals. From June 2015 through
L U Gerdes et al.
The British journal of surgery, 87(6), 760-765 (2000-06-10)
The common polymorphism of the apolipoprotein E (APOE) gene is associated with differential risk of atherosclerosis; the gene could be a candidate gene in abdominal aortic aneurysms (AAA). APOE genotypes were determined in 57 men aged 65-73 years with a
K M Small et al.
The Journal of biological chemistry, 275(30), 23059-23064 (2000-05-10)
The alpha(2)-adrenergic receptors (alpha(2)ARs) play a critical role in modulating neurotransmitter release in the central and peripheral sympathetic nervous systems. A polymorphism of the alpha(2)AR subtype localized to human chromosome 4 (the pharmacologic alpha(2C)AR subtype) within an intracellular domain has
L R Hall et al.
Journal of immunology (Baltimore, Md. : 1950), 141(8), 2781-2787 (1988-10-15)
Ten genomic DNA clones encoding the human leukocyte common Ag (LCA, CD45) gene were isolated by screening human genomic DNA libraries with LCA cDNA probes. One genomic DNA clone contains the promoter region and the first two exons, as determined
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