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Franca Franchi et al.
Haematologica, 89(4), 444-449 (2004-04-13)
Intrauterine growth restriction is an important cause of morbidity and mortality. Its pathogenesis is still a matter of debate. The aim of this study was to evaluate the association between intrauterine growth restriction (diagnosed in utero by serial ultrasound examinations
Na Sun et al.
Journal of food science, 84(5), 1002-1011 (2019-04-13)
Although phosphatidylethanolamine (PE) is an important functional phospholipid, there have been very few reports on its antioxidant activity and corresponding molecular composition. Crude PE was extracted from egg yolk with various solvents, and response surface modeling was carried out to
Tobias Broger et al.
The Lancet. Infectious diseases, 19(8), 852-861 (2019-06-04)
Most tuberculosis-related deaths in people with HIV could be prevented with earlier diagnosis and treatment. The only commercially available tuberculosis point-of-care test (Alere Determine TB LAM Ag [AlereLAM]) has suboptimal sensitivity, which restricts its use in clinical practice. The novel
Marcia M Wright et al.
Lipids, 37(7), 663-672 (2002-09-10)
The human choline/ethanolamine phosphotransferase 1 (CEPT1) gene codes for a dual-specificity enzyme that catalyzes the de novo synthesis of the two major phospholipids through the transfer of a phosphobase from CDP-choline or CDP-ethanolamine to DAG to form PC and PE.
Wonwoo Shon et al.
Journal of cutaneous pathology, 38(12), 961-966 (2011-11-05)
Angiosarcomas may be primary in the skin, primary in soft tissue or viscera, or secondary to irradiation. All angiosarcomas have a poor prognosis. Taxanes may have efficacy in the treatment of angiosarcoma. Expression of TLE3 has been associated with improved
Dimple Kauhanen et al.
Analytical and bioanalytical chemistry, 408(13), 3475-3483 (2016-02-29)
Monitoring the levels of the ceramides (Cer) d18:1/16:0, Cer d18:1/18:0, Cer d18:1/24:0, and Cer d18:1/24:1 and ratios thereof in human plasma empowers the prediction of fatal outcome of coronary artery disease (CAD). We describe a validated liquid chromatography-tandem mass spectrometry
Farhad Mehrkhani et al.
Journal of neuroimaging : official journal of the American Society of Neuroimaging, 28(5), 524-529 (2018-05-12)
Imaging may identify patients with very large infarcts who are unlikely to benefit from intra-arterial therapy. Although computed tomography (CT) is widely used, it suffers from poor sensitivity. We sought to evaluate whether combined evaluation of noncontrast CT (NCCT) and
Colin Patrick Cantwell et al.
Journal of computer assisted tomography, 32(5), 738-744 (2008-10-03)
To compare low-radiation dose non-enhanced fluorine 18 fluorodeoxyglucose (F-18 FDG) positron emission tomography (PET)/computed tomography (CT) (NE-PET/CT), contrast-enhanced fluorine 18 fluorodeoxyglucose PET/CT (CE-PET/CT), and gadolinium-enhanced liver magnetic resonance imaging (MRI) for the detection and characterization of liver lesions in patients
Richard O Adlof et al.
Journal of agricultural and food chemistry, 51(7), 2096-2099 (2003-03-20)
Symmetrical disaturated triacylglycerols of the structure SUS, where S is stearic acid (18:0) and U is an unsaturated fatty acid, either oleic (O; 9cis-18:1), linoleic (L; 9cis,12cis-18:2), or linolenic (Ln; 9cis,12cis,15cis-18:3), are important components providing functionality to interesterified fat blends
Edward B Garon et al.
Lancet (London, England), 384(9944), 665-673 (2014-06-17)
Ramucirumab is a human IgG1 monoclonal antibody that targets the extracellular domain of VEGFR-2. We aimed to assess efficacy and safety of treatment with docetaxel plus ramucirumab or placebo as second-line treatment for patients with stage IV non-small-cell-lung cancer (NSCLC)
Tongfeng Zhao et al.
Clinical endocrinology, 74(2), 214-222 (2010-11-09)
Results from the published studies on the association of adiponectin gene (ADIPOQ) polymorphisms with blood lipids and blood pressure are conflicting. We investigated the association of three ADIPOQ polymorphisms, +45 T > G (rs2241766), +276 G > T (rs1501299) and -11377 C > G (rs266729), with
Ajay Vora et al.
The Lancet. Oncology, 15(8), 809-818 (2014-06-14)
No randomised study has shown whether stratification of treatment by minimal residual disease (MRD) response improves outcome in children and young people with acute lymphoblastic leukaemia (ALL). We assessed whether children and young people with clinical standard and intermediate-risk ALL
Eric D Donnenfeld et al.
Journal of cataract and refractive surgery, 47(2), 158-164 (2020-09-15)
To evaluate the safety and efficacy of a nepafenac punctal plug delivery system (N-PPDS) after cataract surgery. Three U.S. clinical sites. Prospective, multicenter, randomized (2:1), parallel-arm, double-masked, placebo-controlled, phase II pilot study. Fifty-six subjects (aged older than 22 years) with
D E Rico et al.
The British journal of nutrition, 124(4), 386-395 (2020-02-06)
The aim of the present study was to compare the effects of post-ruminally infused fat supplements, varying in fatty acid (FA) chain length, on animal performance, metabolism and milk FA. Eleven multiparous Holstein dairy cows were used in a replicated
Ronghua Dai et al.
Journal of chromatographic science, 42(4), 207-210 (2004-05-25)
High-performance liquid chromatography is employed to determine the contents of six marker components such as mangiferin, jateorrhizine, palmatine, berberine, cinnamic acid, and cinnamaldehyde in the traditional Chinese medicinal preparation Zi-Shen pill. The separation is performed on a C(18) column by
Niikee C Schoendorfer et al.
European journal of clinical investigation, 42(7), 768-776 (2012-02-04)
Methylation cycle and folate-mediated one-carbon metabolism maintenance is important for many physiological processes including neurotransmitter regulation, nerve myelination and DNA synthesis. These processes play an indispensible role in growth and development, as well as in cognitive function and neuromuscular stability
Alessio Imperiale et al.
European journal of nuclear medicine and molecular imaging, 33(12), 1483-1490 (2006-04-29)
Age-related values of (123)I-orthoiodohippurate (OIH) single kidney clearance rate (Cl) were estimated in a large cohort of likely normal children aged between 0 and 18 years. Among 4,111 children examined in the past 10 years, 917 were selected with the
Gary Middleton et al.
The Lancet. Oncology, 15(8), 829-840 (2014-06-24)
We aimed to assess the efficacy and safety of sequential or simultaneous telomerase vaccination (GV1001) in combination with chemotherapy in patients with locally advanced or metastatic pancreatic cancer. TeloVac was a three-group, open-label, randomised phase 3 trial. We recruited patients
C Vipin et al.
Journal of applied microbiology, 126(2), 641-650 (2018-10-30)
The aim of this study was to investigate the natural variation in the antibiotic sensitivity, biofilm formation and virulence among Pseudomonas aeruginosa isolated from the catheter-associated urinary tract infection (CAUTI) from a single centre. Pseudomonas aeruginosa strains were isolated from
Gerhard Binder et al.
Clinical endocrinology, 82(1), 100-105 (2014-09-11)
The distinction between constitutional delay of growth and puberty (CDGP) and isolated hypogonadotropic hypogonadism (IHH) in males with delayed puberty is difficult but important for timely treatment. We assessed the accuracy of the GnRH agonist test (triptorelin 0·1 mg) in
Peter Kämpfer et al.
International journal of systematic and evolutionary microbiology, 64(Pt 5), 1736-1742 (2014-02-21)
A yellow-pigmented, Gram-negative, rod-shaped, non-spore-forming bacterium (strain JM-1070T) was isolated as a presumptive endophyte from internal stem tissue of a healthy corn stem. Phylogenetic analyses based on the 16S rRNA gene sequence placed strain JM-1070T in the monophyletic cluster of
Joseph T Rabban et al.
The American journal of surgical pathology, 34(2), 137-146 (2010-01-12)
Mesonephric remnants of the cervix are vestiges of the embryonic mesonephric system which typically regresses during female development. Uncommonly, hyperplasia of the mesonephric remnants may occur. The differential diagnosis of exuberant mesonephric hyperplasia includes minimal deviation adenocarcinoma of the cervix
F Ducray et al.
Neurology, 72(2), 156-161 (2009-01-14)
alpha-Internexin (INA) is a proneural gene encoding a neurofilament interacting protein that is upregulated in some gliomas, particularly oligodendrogliomas. INA expression was evaluated by immunohistochemistry in a series of 122 gliomas, and correlated to the 1p19q codeletion, a favorable prognostic
W A Moats
Journal of AOAC International, 76(3), 535-540 (1993-05-01)
A simple and sensitive method was developed for determination of cephapirin and its metabolite, desacetylcephapirin, in milk. For extraction/deproteinization, 2 mL 0.2M tetraethylammonium chloride and 28 mL acetonitrile are added to 10 mL milk, and 20 mL clear filtrate (=
Marcia S Brose et al.
Lancet (London, England), 384(9940), 319-328 (2014-04-29)
Patients with radioactive iodine ((131)I)-refractory locally advanced or metastatic differentiated thyroid cancer have a poor prognosis because of the absence of effective treatment options. In this study, we assessed the efficacy and safety of orally administered sorafenib in the treatment
Karim Fizazi et al.
The Lancet. Oncology, 15(13), 1442-1450 (2014-12-03)
Poor prognosis germ-cell tumours are only cured in about half of patients. We aimed to assess whether treatment intensification based on an early tumour marker decline will improve progression-free survival for patients with germ-cell tumours. In this phase 3, multicentre
T L Resende et al.
Journal of dairy science, 98(7), 4785-4799 (2015-05-11)
The objective of this study was to investigate the effect of incremental amounts of ground flaxseed (GFX) on milk yield and concentrations and yields of milk components, milk fatty acids (FA) profile, ruminal metabolism, and nutrient digestibility in dairy cows
Meinolf Suttorp et al.
Leukemia, 32(7), 1657-1669 (2018-06-22)
A total of 156 patients (age range 1.3-18.0 years, median 13.2 years; 91 (58.3%) male) with newly diagnosed CML (N = 146 chronic phase (CML-CP), N = 3 accelerated phase (CML-AP), N = 7 blastic phase (CML-BP)) received imatinib up-front (300, 400, 500 mg/m2, respectively) within a
M Barceló-Fimbres et al.
Theriogenology, 71(2), 355-368 (2008-09-20)
The objective was to evaluate the use of phenazine ethosulfate (PES) during culture of embryos on fetal and postnatal calf development. Oocytes collected from abbatoir-derived ovaries were matured and fertilized, and the resulting embryos were cultured in vitro by standard
Melanie Georgiou et al.
Scientific reports, 8(1), 14440-14440 (2018-09-29)
Olfactory ensheathing cells (OECs) are a promising potential cell therapy to aid regeneration. However, there are significant challenges in isolating and characterizing them. In the current study, we have explored methods to enhance the recovery of cells expressing OEC marker
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