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Dae Woo Lee et al.
Oncology reports, 45(1), 390-400 (2020-11-18)
The present study aimed to analyze the compensatory signaling pathways induced by forkhead domain inhibitor‑6 (FDI‑6), which is a forkhead box protein M1 (FOXM1) inhibitor, in ovarian cancer cells and evaluate the effectiveness of simultaneous inhibition of FOXM1 and the compensatory signaling pathway
Eva Baldrich et al.
Analytical chemistry, 83(6), 2097-2103 (2011-02-18)
n-Acyl homoserine lactones (AHLs) are produced by gram-negative bacteria to regulate gene expression in a cell density dependent manner. For instance, expression of virulence factors by pathogens such as Pseudomonas aeruginosa is induced only when a threshold concentration of AHLs
Nan Li et al.
Analytical chemistry, 85(20), 9699-9704 (2013-08-29)
Cancer is a major global health challenge that would benefit from advances in screening methods for early detection that are rapid and low cost. TF-antigen is a tumor-associated antigen displayed on cell surface proteins of a high percentage of human
D M Belen'kiĭ et al.
Biokhimiia (Moscow, Russia), 48(5), 851-856 (1983-05-01)
The antibodies were prepared from antisera of rabbits immunized with bovine serum albumin containing covalently bound p-aminophenyl-beta-D-galactopyranoside (APG) and purified by affinity chromatography on APG-containing ovalbumin immobilized by BrCN-activated Sepharose 4B. The antibodies possessed a selective specificity for APG and
M Naoi et al.
Journal of neurochemistry, 47(6), 1879-1884 (1986-12-01)
Using a synthesized glycoprotein, beta-galactosidase modified with p-aminophenyl beta-D-galactopyranoside (beta-D-Gal beta-gal), the incorporation of the glycoprotein into bovine brain synaptosomes was studied. The uptake was mediated by a specific receptor to beta-D-galactoside, and was inhibited by GM1 ganglioside. The uptake
Effect of membrane composition on the immune reactivity of galactosylated liposomes.
D P Sarkar et al.
Indian journal of biochemistry & biophysics, 21(3), 155-157 (1984-06-01)
Ardhendu K Mandal et al.
Journal of drug targeting, 13(5), 305-315 (2005-10-04)
Rats were administered a single dose of plant origin phenolic antioxidant Quercetin (QC) in free, liposome encapsulated and galactosylated liposome encapsulated forms 2 h prior to hepatotoxic dose of carbontetrachloride (CCl4, 40% v/v in olive oil, 1 ml/kg b.wt). Among
Daniel Bello-Gil et al.
PloS one, 9(1), e87995-e87995 (2014-02-06)
We have developed a general method for the specific and reversible immobilization of proteins fused to the choline-binding module C-LytA on functionalized graphite electrodes. Graphite electrode surfaces were modified by diazonium chemistry to introduce carboxylic groups that were subsequently used
Ardhendu K Mandal et al.
The Journal of pharmacology and experimental therapeutics, 320(3), 994-1001 (2006-12-02)
Arsenic, the environmental metalloid toxicant, is known to induce oxidative damage to liver and produce hepatic fibrosis. The theme of our study was to optimize and evaluate the therapeutic efficacy of galactosylated liposomal flavonoidal antioxidant, quercetin (QC), in combating arsenic-induced
[p-Aminophenyl-beta-D-galactopyranoside as an antigenic determinant in neoglycoproteins].
D M Belen'kiĭ
Molekuliarnaia biologiia, 17(1), 54-61 (1983-01-01)
D P Sarkar et al.
Immunological communications, 13(1), 5-13 (1984-01-01)
The kinetics of the immune response to galactosylated liposomes in saline was studied in rabbits. The antibody level in the secondary immunization was found to be higher compared to that in the primary response. The antibodies were purified on an
D M Belenky
Biochimica et biophysica acta, 786(3), 197-203 (1984-05-17)
Human liver acid alpha-glucosidase (1,4-alpha-D-glucan glucohydrolase, EC 3.2.1.3) was modified with water soluble carbodiimide in the presence of p-aminophenyl-beta-D-galactopyranoside. The incorporation of the aminophenyl derivative of galactose into alpha-glucosidase caused some changes in the physiocochemical properties of the enzyme: a
Benoît Limoges et al.
Journal of the American Chemical Society, 128(18), 6014-6015 (2006-05-04)
Electrochemical responses (e.g., chronoamperometric) obtained with an immobilized enzyme that produces an electroactive species may be used to quantitate the amount of enzyme or the concentration of its substrate. It is shown, on theoretical and experimental bases, that product-to-substrate coupling
Qijing Chen et al.
Journal of controlled release : official journal of the Controlled Release Society, 323, 179-190 (2020-04-26)
Macrophages are attractive therapeutic targets due to their contributions to many pathological processes including cancers, atherosclerosis, obesity, diabetes and other inflammatory diseases. Macrophage-targeted gene therapy is an effective strategy for regulating macrophage function at the site of inflammation to treat
Takatoshi Kaya et al.
Chemical communications (Cambridge, England), (2)(2), 248-249 (2004-01-23)
[small beta]-Galactosidase expression in a small number of Escherichia coli cells has been measured in real time with an electrochemical sensor chip. E. coli cells were embedded using collagen gel within a micropore which was microfabricated onto a chip. The
D M Belen'kiĭ et al.
Biokhimiia (Moscow, Russia), 47(7), 1141-1146 (1982-07-01)
Chemical modification of the COOH-groups of acid alpha-glucosidase from human liver by 1-ethyl-3 (3'-dimethylaminopropyl) carbodiimide. HCl in the presence of rho-aminophenyl-beta-D-galactopyranoside was carried out. The presence of covalently bound galactose derivative in the enzyme was followed by changes in the
Olivier Laczka et al.
Analytica chimica acta, 677(2), 156-161 (2010-09-15)
Two simple methodologies are compared for the detection of faecal contamination in water using amperometry at gold interdigitated microelectrodes. They rely on the detection of β-galactosidase (β-gal) by redox cycling amperometry of the p-aminophenol (PAP) produced by the enzyme from
D P Sarkar et al.
Immunological communications, 11(3), 175-188 (1982-01-01)
Negatively-charged, multilamellar liposomes, covalently coupled with p-aminophenyl-beta-D-galactopyranoside, elicited the rabbits a nearly equivalent anti-galactosyl immune response in both the presence and the absence of complete Freund's-adjuvant (CFA). The antibody response obtained using liposomes both as the carrier and adjuvant was
Sebastian Buchinger et al.
Analytica chimica acta, 659(1-2), 122-128 (2010-01-28)
Electrochemical signal detection can be readily integrated in biosensors and is thus an attractive alternative to optical detection methods. In the field of environmental chemistry and ecotoxicology there is a growing demand for lab-independent devices based on whole cell biosensors
Olivier Laczka et al.
Analytica chimica acta, 641(1-2), 1-6 (2009-04-28)
Here a novel electrochemical method for the rapid detection of anti-HIV antibodies in serum is presented. The novelty lies in the combination of allosteric enzymes and coulometry to yield a fast, simple and reliable HIV diagnostic method. We have used
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