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关键词:'C0543'
显示 31-60 共 183 条结果 关于 "C0543" 范围 论文
Yuzhu Hou et al.
Journal of immunology (Baltimore, Md. : 1950), 193(1), 130-138 (2014-06-08)
The high temperature requirement A1 (HTRA1) is a potent protease involved in many diseases, including rheumatoid arthritis (RA). However, the regulatory mechanisms that control HTRA1 expression need to be determined. In this study, we demonstrated that IFN-γ significantly inhibited the
Joanne B Tayapad et al.
Current opinion in ophthalmology, 24(4), 288-290 (2013-05-25)
This review presents current data regarding the use of collagen cross-linking in the management of corneal infections. Infectious keratitis can lead to blindness without proper antimicrobial therapy. The disease can still progress and lead to corneal melt despite early detection
Marco Rossi et al.
Investigative ophthalmology & visual science, 54(6), 4148-4157 (2013-05-25)
To evaluate the effect of corneal deswelling prior to a microkeratome and femtosecond (fs) laser cut and the impact of the fs laser energy settings on the tissue surface and collagen quality. Porcine and human corneas were incubated in THIN-C
Schwann Cell Autophagy and Necrosis as Mechanisms of Cell Death by Acanthamoeba
Ismael Castelan-Ramirez, et al.
Journal of Separation Science, 9(6), 458-458 (2020)
Shulei Liu et al.
The Canadian journal of cardiology, 30(12), 1689-1699 (2014-11-25)
Micro-RNA 21 (miR-21) has been shown to contribute to cardiac fibrosis in many diseases. In this study we investigated the role of miR-21 in excessive production of collagen in diabetic cardiomyopathy. The proliferation rate of cardiac fibroblasts was analyzed by
Jonathan E Moore et al.
The British journal of ophthalmology, 98(2), 270-274 (2013-11-30)
Cross-linking of the cornea is usually carried out at a young age as a treatment to manage ectasia. The corneal limbal region contains delicate long-lived stem cells, which could potentially be deleteriously affected by Ultraviolet A (UV-A) radiation. Damage to
Brittany J Behar et al.
Journal of wound care, 23(7), S15-S19 (2014-08-27)
Lower extremity traumatic wounds can be difficult to treat owing to limb ischaemia and large zones of injury. Often, muscle or fasciocutaneous flaps are used in the presence of severe open orthopaedic injuries with soft tissue defects. Sometimes local flaps
Alejandro Arboleda et al.
Investigative ophthalmology & visual science, 55(4), 2731-2738 (2014-03-29)
To evaluate the efficacy of coulomb-controlled iontophoresis (CCI) for delivery of riboflavin prior to corneal collagen cross-linking (CXL). The eyes of 20 8-week-old Lewis rats, subject to epithelium-ON (epi-ON, n = 20 eyes) or epithelium-OFF (epi-OFF, n = 20 eyes)
Jun-Hui Choi et al.
Journal of bioscience and bioengineering, 118(4), 372-377 (2014-04-22)
A thrombolytic protease named kitamase possessing anticoagulant property was purified from edible and medicinal plant Aster yomena (Kitam.) Honda. Kitamase showed a molecular weight of 50 kDa by SDS-PAGE and displayed a strong fibrin zymogram lysis band corresponding to the similar
Ken Nakata et al.
Clinical calcium, 23(12), 1731-1739 (2013-12-03)
Meniscus is one of the most important tissues in knee joint from the biomechanical point of view. Meniscus injury is well known to cause osteoarthritis. At moment, there is a limitation of operative repair procedure especially for the meniscus injury
Paolo Vinciguerra et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(11), 746-753 (2014-11-07)
To report initial clinical results of transepithelial corneal collagen cross-linking with iontophoresis (I-CXL). Twenty eyes of 20 patients diagnosed as having progressive keratoconus who underwent I-CXL were included in this prospective non-randomized clinical study. Corrected distance visual acuity (CDVA), spherical
James R W Conway et al.
Nature reviews. Cancer, 14(5), 314-328 (2014-04-18)
Integrating biological imaging into early stages of the drug discovery process can provide invaluable readouts of drug activity within complex disease settings, such as cancer. Iterating this approach from initial lead compound identification in vitro to proof-of-principle in vivo analysis
PACK-CXL: defining CXL for infectious keratitis.
Farhad Hafezi et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(7), 438-439 (2014-07-02)
Daichi Morikawa et al.
Journal of shoulder and elbow surgery, 23(5), 628-635 (2014-04-22)
Rotator cuff degeneration is one of the multiple factors that lead to rotator cuff tears; however, the precise mechanism of such degeneration still remains unclear. In this study, we investigated the supraspinatus tendon enthesis to clarify the link between rotator
Omar Z Ameer et al.
American journal of physiology. Heart and circulatory physiology, 307(2), H143-H151 (2014-05-20)
This study investigated the effects of hypertension on regional aortic biomechanical and structural properties in three rat models of vascular calcification: the hypertensive Lewis polycystic kidney (LPK; n = 13) model of chronic kidney disease, spontaneously hypertensive rats (SHRs; n
Atsushi Kimura et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(10), 2015-2031 (2014-05-27)
The aim of the present study was to evaluate the feasibility of a gelatin hydrogel system to enhance recombinant human fibroblast growth factor-2 (rhFGF-2)-induced osteogenic effects during rat mandibular distraction. Mandibular distraction was performed in 28 male Wistar rats. Then
J H Darrien et al.
Annals of the Royal College of Surgeons of England, 96(4), 271-274 (2014-05-02)
Gastrocutaneous fistulas remain an uncommon complication of upper gastrointestinal surgery. Less common but equally problematic are gastrocutaneous fistulas secondary to non-healing gastrostomies. Both are associated with considerable morbidity and mortality. Surgical repair remains the gold standard of care. For those
Xiaofeng Zhu et al.
Zoological science, 30(12), 1032-1037 (2013-12-11)
Autologous bone marrow-derived mesenchymal stem cell (BMSCs)-based therapies show great potential in regenerative medicine. However, long-term storage and preservation of BMSCs for clinical use is still a great clinical challenge. The present study aimed to analyze the effect of long-term
Xiaoyu Liu et al.
Investigative ophthalmology & visual science, 55(4), 2739-2746 (2014-04-03)
To develop a mechanical model with which to investigate the relationship between the crimping morphology of collagen fibrils and the nonlinear mechanical behavior of the cornea. Uniaxial tensile experiments were performed with corneal strips to test their mechanical behavior. A
N Grotenhuis et al.
The British journal of surgery, 101(8), 983-992 (2014-05-20)
Macrophages play an important role in the reaction to biomaterials, which sometimes have to be used in a surgical field at risk of contamination. The macrophage phenotype in reaction to biomaterials in an inflammatory environment was evaluated in both an
Christopher M Runyan et al.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 72(5), 1000-1000 (2014-04-20)
"Allograft revitalization" is a process in which cadaveric bone is used to generate well-vascularized living bone. We had previously found that porcine allograft hemimandibles filled with autologous adipose-derived stem cells (ASCs) and recombinant human bone morphogenetic protein-2-soaked absorbable collagen sponge
Dividutta Das et al.
The Journal of heart valve disease, 22(5), 621-630 (2014-01-05)
Aortic valve stenosis is a major cause of valve replacement, particularly in the elderly. TGF-beta1 is upregulated in stenotic valves and induces calcification and collagen synthesis in cultured valve interstitial cells. It has been shown previously that TGF-beta1 increases reactive
An unusual finding in a man with GERD.
Garrett M Harp et al.
Gastroenterology, 147(2), e7-e9 (2014-06-29)
The needle in the ECM haystack.
Karl E Kadler
Nature reviews. Molecular cell biology, 15(12), 769-769 (2014-10-31)
Roger Svensson et al.
Swedish dental journal, 37(2), 71-77 (2013-08-21)
The aim of this retrospective study was to assess the frequency of postoperative bleeding in patients on warfarin after tooth removal followed by a complete soft tissue closure of the surgical site. A total of 124 consecutive patients, 69 males
Thanh-Thuy T Le et al.
Journal of immunology (Baltimore, Md. : 1950), 193(7), 3755-3768 (2014-08-31)
Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease with progressive fibrosis and death within 2-3 y of diagnosis. IPF incidence and prevalence rates are increasing annually with few effective treatments available. Inhibition of IL-6 results in the attenuation of
Hesam Hashemian et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 30(12), 837-842 (2014-12-02)
To evaluate the outcome of accelerated and conventional corneal cross-linking (CXL) procedures regarding their effect on morphological and optical properties of the cornea. One hundred fifty-three eyes of 153 patients were evaluated before and during a 15-month follow-up period after
Abel Arul Nathan et al.
Tropical medicine & international health : TM & IH, 22(11), 1414-1427 (2017-09-05)
The underlying problem in lymphatic filariasis is irreversible swelling of the limbs (lymphoedema), which is a unique feature of lymphatic insufficiency. It is still unclear whether the natural ability of lymphatics to form functional lymphatic vasculature is achieved or attenuated
Leonardo Mastropasqua et al.
Investigative ophthalmology & visual science, 55(4), 2526-2533 (2014-03-29)
The aim of this study is to investigate modifications in human cadaver corneas after different crosslinking procedures, including standard epi-off treatment, iontophoresis imbibition, and different exposure to ultraviolet A (UVA) sources (30 minutes at 3 mW and 9 minutes at
Yuxin Pang et al.
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 34(6), 716-724 (2015-01-27)
To assess the effectiveness of violate oil from Blumea Balsamifera (L.) DC. leaves (BB oil) on wound healing in mice. Undiluted BB oil and its diluted solutions with olive oil to 1/5 and 1/10 to yield BB oil1/5 and BB
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