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Krystal Nizar et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(19), 8411-8422 (2013-05-10)
Calcium-dependent release of vasoactive gliotransmitters is widely assumed to trigger vasodilation associated with rapid increases in neuronal activity. Inconsistent with this hypothesis, intact stimulus-induced vasodilation was observed in inositol 1,4,5-triphosphate (IP3) type-2 receptor (R2) knock-out (KO) mice, in which the
7.5% saline and 7.5% saline/6% dextran for hypovolemic shock.
Eileen M Bulger
The Journal of trauma, 70(5 Suppl), S27-S29 (2011-06-15)
Zhiyang Li et al.
Journal of biomedical nanotechnology, 9(11), 1945-1949 (2013-09-26)
For reducing the steric hindrance and nonspecific binding of the target DNA, the dextran was used as molecular arms to be immobilized on the surface of magnetic nanoparticles (MNPs). Magnetic separation was used in preparation of dextran-MNPs (DMNPs). Aspartic acid
P Roderick et al.
Health technology assessment (Winchester, England), 9(49), iii-iiv (2005-12-13)
To assess the benefits in terms of reductions in the risks of deep vein thrombosis (DVT) and of pulmonary embolism (PE), and hazards in terms of major bleeding, of: (i) mechanical compression; (ii) oral anticoagulants; (iii) dextran; and (iv) regional
Jorawer S Singh et al.
Experimental eye research, 115, 239-245 (2013-07-09)
Corneal endothelial cells form a leaky barrier on the posterior surface of the cornea, allowing influx of nutrient-carrying aqueous humor through the paracellular space and efflux of excess fluid. Corneal edema arises when the density of these non-proliferative endothelial cells
Do Hyung Kim et al.
Nanoscale research letters, 7(1), 91-91 (2012-01-31)
Sorafenib-incoporated nanoparticles were prepared using a block copolymer that is composed of dextran and poly(DL-lactide-co-glycolide) [DexbLG] for antitumor drug delivery. Sorafenib-incorporated nanoparticles were prepared by a nanoprecipitation-dialysis method. Sorafenib-incorporated DexbLG nanoparticles were uniformly distributed in an aqueous solution regardless of
Elisa Crisci et al.
Molecular immunology, 63(2), 343-354 (2014-10-06)
Cellular therapies using immune cells and in particular dendritic cells (DCs) are being increasingly applied in clinical trials and vaccines. Their success partially depends on accurate delivery of cells to target organs or migration to lymph nodes. Delivery and subsequent
Xing-Bo Li et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(10), 1543-1547 (2013-08-21)
Sixteen compounds were isolated from Conioselinum vaginatum by silica column chromatography over silica gel and Sephadex LH-20, as well as recrystallization. On the basis of their physical and chemical properties and spectral data, their structures were identified as ligustilide (1)
Xiao-Yu Tao et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(24), 3738-3742 (2013-05-01)
The column chromatography on silica gel, Sephadex LH-20 and semi-preparative HPLC were used to separate and purify the compounds from the EtOAc extract of medium and MeOH extract of cell cultures of Morus alba. Eight compounds were isolated. Based on
Gordon M Riha et al.
The journal of trauma and acute care surgery, 75(1), 129-134 (2013-08-14)
Previous studies have shown large-volume resuscitation modulates coagulopathy and inflammation. Our objective was to analyze the effects of initial bolus fluids used in military and civilian settings on coagulation and inflammation in a prospective, randomized, blinded trial of resuscitation of
Aline Mendes Maziero et al.
Life sciences, 93(9-11), 416-422 (2013-07-23)
The relationship between the activity of eosinophils and platelets has been observed in recent decades by many scientists. These observations include increased numbers of eosinophils associated with platelet disorders, including changes in the coagulation cascade and platelet aggregation. Based on
Editorial comment.
Kathleen Kieran
Urology, 83(4), 922-923 (2014-01-15)
Faming Chen et al.
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 19(11), 919-922 (2005-12-13)
To introduce the development of dextran-based hydrogel and its drug delivery system in drug sustained and/or controlled release, and to investigate their application in tissue engineering. Related literature was extensively reviewed and comprehensively analyzed. In recent years, great progress was
[The effect of HES, dextran and gelatin on kidney function].
N Vogt et al.
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS, 33(4), 268-270 (1998-06-09)
Non-adsorbing macromolecules promote endothelial adhesion of erythrocytes with reduced sialic acids.
Yang Yang et al.
Biochimica et biophysica acta, 1840(1), 288-293 (2013-10-01)
Abnormal adhesion of red blood cells (RBCs) to vascular endothelium is often associated with reduced levels of sialic acids on RBC membranes and with elevated levels of pro-adhesive plasma proteins. However, the synergistic effects of these two factors on the
Michael J Pitman et al.
The Annals of otology, rhinology, and laryngology, 122(4), 283-287 (2013-05-24)
We investigated the quantity of recurrent laryngeal nerve motoneurons (RLNMs) that survive after transection and anastomosis of the rat recurrent laryngeal nerve (RLN), as well as the impact of the anastomosis site on RLN regeneration. Ten rats underwent right RLN
Maharajan Sivasubramanian et al.
Carbohydrate polymers, 97(2), 643-649 (2013-08-06)
The extensive therapeutic potential of protein drugs has been severely limited by their instability and short biological half-lives in vivo. To prolong their therapeutic effects, a sustained delivery system is required. In this study, cyclodextrin-based polymeric nanoparticles (CD-NPs), mineralized by
Giuseppe Gambino et al.
Biomaterials, 34(29), 7135-7142 (2013-06-25)
We developed and examined the applicability of two multimodal paramagnetic contrast agents for the longitudinal in vivo investigations of the brain projections. The classical dextran based neuroanatomical tracer was conjugated with mono- and bimetal Gd(3+) complexes and an optical reporter.
Sabine Kling et al.
Journal of refractive surgery (Thorofare, N.J. : 1995), 29(7), 490-497 (2013-07-04)
To evaluate corneal deformation with varying intraocular pressure and the dependency of the biomechanical response on the corneal hydration state, modulated by the storage solutions or postmortem period. Thirty fresh enucleated porcine eyes were used for in vitro whole eye
George P Liao et al.
The Journal of surgical research, 190(2), 628-633 (2014-06-08)
Blood brain barrier (BBB) compromise is a key pathophysiological component of secondary traumatic brain injury characterized by edema and neuroinflammation in a previously immune-privileged environment. Current assays for BBB permeability are limited by working size, harsh extraction processes, suboptimal detection
Yoshikazu Isomura et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(25), 10209-10220 (2013-06-21)
It is widely accepted that dorsal striatum neurons participate in either the direct pathway (expressing dopamine D1 receptors) or the indirect pathway (expressing D2 receptors), controlling voluntary movements in an antagonistically balancing manner. The D1- and D2-expressing neurons are activated
Lamiaa M A Ali et al.
Journal of biomedical nanotechnology, 9(7), 1272-1285 (2013-08-06)
Superparamagnetic iron oxide nanoparticles (SPIONs) are inorganic nanomaterials gaining strong clinical interest due to their increasing number of biological and medical applications. The stabilization of SPIONs in a biocompatible stable suspension (bioferrofluid) is generally achieved by an adequate polymeric coating.
Alexander Zhbanov et al.
PloS one, 10(6), e0129337-e0129337 (2015-06-06)
The erythrocyte sedimentation rate (ESR) test has been used for over a century. The Westergren method is routinely used in a variety of clinics. However, the mechanism of erythrocyte sedimentation remains unclear, and the 60 min required for the test
Yulia Shandalov et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(16), 6010-6015 (2014-04-09)
Large soft tissue defects involve significant tissue loss, requiring surgical reconstruction. Autologous flaps are occasionally scant, demand prolonged transfer surgery, and induce donor site morbidity. The present work set out to fabricate an engineered muscle flap bearing its own functional
G Dolton et al.
Clinical and experimental immunology, 177(1), 47-63 (2014-03-29)
Fluorochrome-conjugated peptide-major histocompatibility complex (pMHC) multimers are widely used for flow cytometric visualization of antigen-specific T cells. The most common multimers, streptavidin-biotin-based 'tetramers', can be manufactured readily in the laboratory. Unfortunately, there are large differences between the threshold of T
Kelli G Sharp et al.
Experimental neurology, 257, 186-204 (2014-04-22)
As part of the NIH "Facilities of Research Excellence-Spinal Cord Injury" project to support independent replication, we repeated key parts of a study reporting robust engraftment of neural stem cells (NSCs) treated with growth factors after complete spinal cord transection
Ji Hong Hwang et al.
Biochimie, 95(10), 1917-1922 (2013-07-03)
In this study, the antifungal activity and mode of action(s) of hibicuslide C derived from Abutilon theophrasti were investigated. Antifungal susceptibility testing showed that hibicuslide C possessed potent activities toward various fungal strains and less hemolytic activity than amphotericin B.
Molecular Weight Effects on the Miscibility Behavior of Dextran and Maltodextrin with Poly(vinylpyrrolidone).
Van Eerdenbrugh B, Taylor LS.
Pharmaceut. Res., doi: 10-doi: 10 (2012)
Veronica L Novosad et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(6), G418-G426 (2013-07-23)
Injury to the intestinal mucosa is a life-threatening problem in a variety of clinical disorders, including hemorrhagic shock, trauma, burn, pancreatitis, and heat stroke. The susceptibility to injury of different regions of intestine in these disorders is not well understood.
Qing-Qing Wang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 38(3), 366-370 (2013-05-15)
To study the chemical constituents of Rhododendron seniavinii. Compounds were isolated from the aqueous extract of the leaves of R. seniavinii by using Sephadex LH-20, ODS open column chromatography and other means. Their structures were elucidated according to spectral data
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