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Matej Adámik et al.
Biochemical and biophysical research communications, 456(1), 29-34 (2014-12-03)
Site-specific DNA recognition and binding activity belong to common attributes of all three members of tumor suppressor p53 family proteins: p53, p63 and p73. It was previously shown that heavy metals can affect p53 conformation, sequence-specific binding and suppress p53
Determination of vanadium in groundwater samples with an improved kinetic spectrophotometric method.
Esra Bağda
Environmental technology, 35(9-12), 1165-1174 (2014-04-08)
A kinetic catalytic method has been developed for the determination of vanadium based on its catalytic effect on the redox reaction of azorubin S and bromate in the presence of a sulphuric and nitric acid mixture. The reaction is monitored
Theodore A Craig et al.
Biochemical and biophysical research communications, 433(4), 508-512 (2013-03-26)
The EF-hand protein, DREAM/KChIP3 (henceforth referred to as DREAM), regulates apoptosis by incompletely understood mechanisms. We demonstrate that in the presence of Ca2+, DREAM interacts with hexokinase I, a protein known to bind mitochondria and regulate apoptosis. A mutant DREAM
Mingqiang Li et al.
Biomaterials, 51, 161-172 (2015-03-17)
As a synergistic drug combination, doxorubicin-loaded cisplatin crosslinked polysaccharide-based nanoparticles (Dex-SA-DOX-CDDP) have demonstrated enhanced antitumor efficacy and reduced systemic toxicity via optimized biodistribution, controlled drug release, prolonged blood circulation, and improved tolerability, compared to the non-crosslinked nanoparticles or free doxorubicin.
Lili Ma et al.
Molecular medicine reports, 12(2), 2529-2538 (2015-05-09)
Premature ovarian failure (POF) is an ovarian defect characterized by the premature depletion of ovarian follicles in individuals <40 years old, and is a major cause of infertility in females. Genetic factors are considered to be responsible for the development
Naoko Ohashi et al.
The American journal of emergency medicine, 31(7), 1157-1157 (2013-05-25)
EDTA-dependent pseudothrombocytopenia (EDTA-PTCP) is a phenomenon that occurs in vitro when EDTA reacts with harvested blood. EDTA-dependent pseudothrombocytopenia usually does not indicate thrombocytopenia in vivo. Here, we report the first case of EDTA-PTCP complicated by eosinophilic pneumonia. A 70-year-old man
Iman Tahmasbian et al.
Environmental monitoring and assessment, 185(11), 8847-8860 (2013-05-21)
The application of electrical fields and chelating agents is an innovative hybrid technology used for the decontamination of soil polluted by heavy metals. The effects of four center-oriented electrical fields and chelating agents on active fractions of lead and zinc
Samuel T Coradetti et al.
eLife, 7 (2018-03-10)
The basidiomycete yeast Rhodosporidium toruloides (also known as Rhodotorula toruloides) accumulates high concentrations of lipids and carotenoids from diverse carbon sources. It has great potential as a model for the cellular biology of lipid droplets and for sustainable chemical production.
Jose Manuel Vagace et al.
Journal of clinical pathology, 66(9), 811-814 (2013-06-01)
We investigated the case of a 14-year-old girl with an ethylenediaminetetraacetic acid (EDTA)-dependent haemagglutination detected by macrocytosis, which was only evident by an abnormal red blood cell (RBC) population in the histogram. Investigations included haemograms with different anticoagulants and experimental
Carolina Kato Prado et al.
Food additives & contaminants. Part B, Surveillance, 8(2), 81-84 (2014-09-24)
The aim of this study was to investigate the presence of tetracycline residues in pasteurised cow's milk using high-performance liquid chromatography coupled with UV/VIS detection to determine the exposure of Brazilian's population to antibiotic residues. One hundred samples collected from
Catherine W Macharia-Mutie et al.
Public health nutrition, 16(9), 1605-1613 (2012-12-12)
Simulating the probable impact of grain amaranth and highly absorbable, low-Fe micronutrient powder (MNP) on Fe status in a potential target population is an essential step in choosing and developing an appropriate actual intervention. We simulated the potential effect of
Chien-Hui Chien et al.
STAR protocols, 5(2), 103136-103136 (2024-06-14)
Peyer's patches, splenic, and peritoneal B cells induce regulatory T (Treg-of-B) cells in vitro without exogenous chemicals and cytokines. Treg-of-B cells exert suppressive function both in vitro and in vivo. Here, we demonstrate experimental procedures for the generation and characterization of Treg-of-B cells.
Concerns about reliability in the Trial to Assess Chelation Therapy (TACT).
Steven E Nissen
JAMA, 309(12), 1293-1294 (2013-03-28)
S N Kozlov et al.
Zhurnal mikrobiologii, epidemiologii, i immunobiologii, (2)(2), 3-12 (2013-06-29)
Detection ofproteases in outer membranes (OM) of ompT+ and ompT- Vibrio cholerae strains of O1 and O139 serogroups. Specific sterile preparations of OM were obtained by lysis of live V. cholerae cells by 4.5 M urea solution with subsequent differential
Emily Hodges et al.
Nature protocols, 4(6), 960-974 (2009-05-30)
Complementary techniques that deepen information content and minimize reagent costs are required to realize the full potential of massively parallel sequencing. Here, we describe a resequencing approach that directs focus to genomic regions of high interest by combining hybridization-based purification
J Y Hilary Wong et al.
Learning & memory (Cold Spring Harbor, N.Y.), 28(2), 53-71 (2021-01-17)
Discrimination of sensory signals is essential for an organism to form and retrieve memories of relevance in a given behavioral context. Sensory representations are modified dynamically by changes in behavioral state, facilitating context-dependent selection of behavior, through signals carried by
Sonia Rodríguez-Fdez et al.
Nature communications, 11(1), 5808-5808 (2020-11-18)
Skeletal muscle promotes metabolic balance by regulating glucose uptake and the stimulation of multiple interorgan crosstalk. We show here that the catalytic activity of Vav2, a Rho GTPase activator, modulates the signaling output of the IGF1- and insulin-stimulated phosphatidylinositol 3-kinase
S de Vries et al.
Poultry science, 93(8), 2010-2017 (2014-06-17)
Marker methodologies to measure ileal and total tract digestibilities of diets varying in content and degradability of dietary fiber in broiler chickens were evaluated. Chromium sesquioxide (Cr2O3) and cobalt-ethylenediamine tetraacetic acid (Co-EDTA) were used as markers of solid and soluble
Tamar B Wissing et al.
Frontiers in bioengineering and biotechnology, 7, 87-87 (2019-05-14)
In situ tissue engineering is a technology in which non-cellular biomaterial scaffolds are implanted in order to induce local regeneration of replaced or damaged tissues. Degradable synthetic electrospun scaffolds are a versatile and promising class of biomaterials for various in
Gervasio A Lamas et al.
American heart journal, 168(1), 37-44 (2014-06-24)
Disodium ethylenediaminetetraacetic acid (EDTA) reduced adverse cardiac outcomes in a factorial trial also testing oral vitamins. This report describes the intent-to-treat comparison of the 4 factorial groups overall and in patients with diabetes. This was a double-blind, placebo-controlled, 2 ×
Salah Al Zadjali et al.
International journal of clinical and experimental medicine, 8(5), 7160-7167 (2015-07-30)
Lead is a widely-spread environmental pollutant and a commonly-used industrial chemical that can cause multisystemic adverse health effects. However, the effects of lead exposure on diabetic animals have not been reported so far. The aim of this study is to
Luminita David et al.
Colloids and surfaces. B, Biointerfaces, 122, 767-777 (2014-09-02)
This research aimed at reporting the synthesis, characterization and evaluation of the anti-inflammatory effects of some new biomaterials based on silver nanoparticles and polyphenols rich natural extracts. A fast and eco-friendly extracellular biosynthesis of silver nanoparticles (AgNPs), using European black
Lara Marrone et al.
Human molecular genetics, 31(16), 2693-2710 (2022-03-22)
Hereditary spastic paraplegia type 15 (HSP15) is a neurodegenerative condition caused by the inability to produce SPG15 protein, which leads to lysosomal swelling. However, the link between lysosomal aberrations and neuronal death is poorly explored. To uncover the functional consequences
Ilya B Zavodnik et al.
Life sciences, 92(23), 1110-1117 (2013-05-07)
The present study was designed for further evaluation of the biochemical mechanism of hepatic mitochondrial dysfunction under oxidative damages induced by organic hydroperoxide, tert-butyl hydroperoxide (tBHP), for estimation of the molecular targets impaired during oxidative stress, and for investigation of
[Alternative medicine sensation. Surprisingly effective: chelates and multivitamins in coronary heart disease].
Dirk Einecke
MMW Fortschritte der Medizin, 155(6), 23-23 (2013-05-25)
Quan Zhang et al.
Environmental science & technology, 48(12), 6995-7001 (2014-05-23)
As the substitute of polybrominated diphenyl ethers (PBDEs), further assessments about the potential ecological safety and health risks of phosphorus-containing flame retardants (PFRs) are required because the worldwide demand for PFRs has been increasing every year. In this study, we
O-GlcNAcylation is crucial for sympathetic neuron development, maintenance, functionality and contributes to peripheral neuropathy.
Wu, et al.
Frontiers in Neuroscience, 17, 1137847-1137847 (2023)
Q Chu et al.
Cell proliferation, 46(3), 254-262 (2013-05-23)
Human CAP10-like protein 46 kDa (hCLP46), also known as Poglut1, has been shown to be an essential regulator of Notch signalling. hCLP46 is overexpressed in primary acute myelogenous leukaemia, T-acute lymphoblastic leukaemia samples and other leukaemia cell lines. However, effects
M C Wiltbank et al.
Biology of reproduction, 40(6), 1194-1200 (1989-06-01)
The activity and steroidogenic action of protein kinase C were evaluated in small and large steroidogenic ovine luteal cells. Protein kinase C activity (per mg protein) was threefold greater in large than in small luteal cells, whereas protein kinase A
Peter Schuff-Werner et al.
British journal of haematology, 162(5), 684-692 (2013-07-03)
Pseudothrombocytopenia remains a challenge in the haematological laboratory. The pre-analytical problem that platelets tend to easily aggregate in vitro, giving rise to lower platelet counts, has been known since ethylenediamine-tetra acetic acid EDTA and automated platelet counting procedures were introduced
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