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Stuart B Krasnoff et al.
Journal of natural products, 77(7), 1685-1692 (2014-07-06)
Under iron-depleted culture conditions, the entomopathogenic fungus Metarhizium robertsii (Bischoff, Humber, and Rehner) (= M. anisopliae) produces a complex of extracellular siderophores including novel O-glycosylated and N-oxidized coprogen-type compounds as well as the known fungal siderophores N(α)-dimethylcoprogen (NADC) and dimerumic
Joseph D Mancias et al.
Nature, 509(7498), 105-109 (2014-04-04)
Autophagy, the process by which proteins and organelles are sequestered in double-membrane structures called autophagosomes and delivered to lysosomes for degradation, is critical in diseases such as cancer and neurodegeneration. Much of our understanding of this process has emerged from
Ramesh Kumar et al.
Environmental technology, 35(13-16), 2018-2027 (2014-06-25)
Nanofiltration (NF) of ammoniacal wastewater containing phenol and cyanide has been investigated for effective separation of these hazardous pollutants and for the subsequent downstream chemical treatment resulting in valuable by-product generation. Four different types of composite polyamide commercial NF membranes
Vivek Kumar Srivastava et al.
The Biochemical journal, 463(1), 103-114 (2014-07-06)
Iron is an essential nutrient for all living organisms and human pathogens employ a battery of factors to scavenge iron from the high-affinity iron-binding host proteins. In the present study, we have elucidated, via a candidate gene approach, major iron
Florence Lima et al.
Environmental and molecular mutagenesis, 55(3), 266-277 (2014-04-12)
DNA methylation is an epigenetic mechanism that drives phenotype and that can be altered by environmental exposures including radiation. The majority of human radiation exposures occur in a relatively low dose range; however, the biological response to low dose radiation
Koichiro Uto et al.
Journal of nanoscience and nanotechnology, 14(4), 3193-3201 (2014-04-17)
(Apo)ferritins are cage-shaped proteins which have recently received a great deal of attention because the inner cavity of the protein shell can be used as a size-restricted reaction field for the synthesis of nanomaterials. The biomineralization behavior and inorganic nanoparticle
Sandra Isabel Escobar-Megchún et al.
Journal of water and health, 12(4), 722-726 (2014-12-05)
This study relates to a method for evaluating the degradation efficiency of Ascaris lumbricoides eggs through a Fenton reaction, using hydrogen peroxide (H2O2) at 100, 250, and 500 mg/L, ferrous sulfate (FeSO4) at 458 mg/L Fe(2+) and pH values of
Shuichi Sekine et al.
Toxicology and applied pharmacology, 282(3), 237-243 (2014-12-30)
Patients with long-lasting hepatitis C virus (HCV) infection are at major risk of hepatocellular carcinoma (HCC). Iron accumulation in the livers of these patients is thought to exacerbate conditions of oxidative stress. Transgenic mice that express the HCV core protein
Jun-Won Jang et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 59(12), 2503-2507 (2009-06-23)
Zero valent iron has been successfully used for the degradation of a wide range of contaminants. However, this reaction of using ZVI particle produces a large quantity of iron sludge. To solve the problem, we report the synthesis of self-organized
Ewelina Łukaszyk et al.
Przeglad lekarski, 71(2), 95-97 (2014-07-16)
Subclinical inflammation is one of the key mechanisms responsible for the development and progression of chronic kidney disease. It may stem from uremia, ongoing inflammation in kidney as well as latent bacterial and viral infections. Inflammation also plays a significant
Yingxun Liu et al.
Journal of biomedical nanotechnology, 10(8), 1574-1587 (2014-07-16)
To evaluate the effects of iron oxide nanoparticles on genes from different cell lines in this study, mouse macrophage RAW264.7 and hepatocyte Hepa1-6 cell lines were treated with DMSA-coated Fe3O4 nanoparticles. Two doses were used, 50 microg/mL and 100 microg/mL
Corrosion of iron by iodide-oxidizing bacteria isolated from brine in an iodine production facility.
Satoshi Wakai et al.
Microbial ecology, 68(3), 519-527 (2014-05-28)
Elemental iodine is produced in Japan from underground brine (fossil salt water). Carbon steel pipes in an iodine production facility at Chiba, Japan, for brine conveyance were found to corrode more rapidly than those in other facilities. The corroding activity
Julia Steuber et al.
Nature, 516(7529), 62-67 (2014-12-05)
NADH oxidation in the respiratory chain is coupled to ion translocation across the membrane to build up an electrochemical gradient. The sodium-translocating NADH:quinone oxidoreductase (Na(+)-NQR), a membrane protein complex widespread among pathogenic bacteria, consists of six subunits, NqrA, B, C
Nanda Kumar N Shanmugam et al.
Journal of immunology (Baltimore, Md. : 1950), 193(3), 1398-1407 (2014-06-29)
States of chronic inflammation such as inflammatory bowel disease are often associated with dysregulated iron metabolism and the consequent development of an anemia that is caused by maldistribution of iron. Abnormally elevated expression of the hormone hepcidin, the central regulator
James C Barton et al.
The American journal of the medical sciences, 349(1), 50-55 (2015-01-07)
Primary iron overload in African Americans has been reported predominantly from autopsy studies. We characterized hepatic iron phenotypes in 83 African Americans who underwent liver biopsy during the interval 1990 to 1995. We tabulated pathology report form data, iron grades
David Z Mokry et al.
Biochimica et biophysica acta, 1840(10), 3058-3066 (2014-06-28)
For many pathogenic microorganisms, iron acquisition represents a significant stress during the colonization of a mammalian host. Heme is the single most abundant source of soluble iron in this environment. While the importance of iron assimilation for nearly all organisms
[Cutting-edge of medicine; iron metabolism--recent findings].
Hideo Harigae
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 102(10), 2699-2704 (2014-01-10)
Maria Wilhelm et al.
Clinical nephrology, 81(4), 251-258 (2014-03-25)
Hyperphosphatemia in advanced chronic kidney disease (CKD) necessitates the use of phosphate binders. This in vitro study assessed phosphate binding and Fe release properties of the novel iron-based phosphate binder PA21. Phosphate adsorption and Fe release were assessed under conditions
Ahmad Al-As'ad et al.
Environmental technology, 35(13-16), 1630-1638 (2014-06-25)
The use of coagulation and Fenton oxidation was studied for total organic carbon (TOC) and silica removal from steam-assisted gravity drainage (SAGD) water at 800C and two different concentrations replicating the stream feeding the warm lime softening unit having 675
Courtni E Allen et al.
Journal of bacteriology, 197(3), 553-562 (2014-11-19)
The use of hemin iron by Corynebacterium diphtheriae requires the DtxR- and iron-regulated ABC hemin transporter HmuTUV and the secreted Hb-binding protein HtaA. We recently described two surface anchored proteins, ChtA and ChtC, which also bind hemin and Hb. ChtA
Mohiee El-Deen El-Aziz Awad et al.
Journal of the Egyptian Society of Parasitology, 44(3), 695-708 (2015-02-04)
This study assessed the diagnostic approaches of Helicobacter pylori (IP)-associated iron deficiency (ID) and anemia (IDA) in children with dyspeptic symptoms and evaluated the effect of simultaneous anti-H. pylori (anti-HIP) therapy and oral iron in comparison with each of anti?
Biochemistry. Fishing for peroxidase protons.
John T Groves et al.
Science (New York, N.Y.), 345(6193), 142-143 (2014-07-12)
Antonino Missineo et al.
Infection and immunity, 82(6), 2448-2459 (2014-04-02)
Staphylococcus lugdunensis is a coagulase-negative staphylococcus that is a commensal of humans and an opportunistic pathogen. It can cause a spectrum of infections, including those that are associated with the ability to form biofilm, such as occurs with endocarditis or
Alexander Liberman et al.
The Journal of surgical research, 190(2), 391-398 (2014-06-29)
High intensity-focused ultrasound (HIFU) is an alterative ablative technique currently being investigated for local treatment of breast cancer and fibroadenomas. Current HIFU therapies require concurrent magnetic resonance imaging monitoring. Biodegradable 500 nm perfluoropentane-filled iron-silica nanoshells have been synthesized as a sensitizing
V N Marty et al.
Radiation research, 182(6), 653-665 (2014-11-18)
The evaluation of potential health risks associated with neuronal exposure to space radiation is critical for future long duration space travel. The purpose of this study was to evaluate and compare the effects of low-dose proton and high-energy charged particle
Oriana Marques et al.
Cancer letters, 347(1), 1-14 (2014-02-04)
Iron is an essential element and a critical component of molecules involved in energy production, cell cycle and intermediate metabolism. However, the same characteristic chemistry that makes it so biologically versatile may lead to iron-associated toxicity as a consequence of
Microcytic anemia.
Thomas G DeLoughery
The New England journal of medicine, 371(14), 1324-1331 (2014-10-02)
Angelo Belotti et al.
Leukemia research, 39(1), 88-91 (2014-12-02)
We analyzed appearance of non transferrin bound iron (NTBI) in 30 transplant eligible patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL) during conventional chemotherapy treatment program and evaluated possible relationship with transfusional body iron intake, iron parameters
Yukio Miyamoto et al.
AJR. American journal of roentgenology, 202(4), W400-W407 (2014-03-26)
The objective of our study was to compare the efficacy of contrast-enhanced ultrasound (CEUS) using the ultrasound contrast agent Sonazoid (perflubutane) with unenhanced ultrasound and supplementary contrast-enhanced MRI in the differential diagnosis (benign vs malignant) of focal breast lesions. The
Mary K Sherwood et al.
Chemosphere, 113, 56-61 (2014-07-30)
Modified Fenton (MF) chemistry was tested in the laboratory to treat three diesel fuel-contaminated soils from the Canadian arctic rich in soil organic matter (SOM) and Fe oxides. Reactors were dosed with hydrogen peroxide (HP), and treatment was compared in
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