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Aurélie Frankart et al.
Archives of dermatological research, 304(4), 289-303 (2012-01-25)
Models of reconstructed human epidermis (RHE) holding proliferating and fully differentiated cultured keratinocytes allow in vitro investigation of early molecular and cellular epidermal events during the complex response of keratinocytes at the onset of allergic contact dermatitis (ACD) or sensitization.
Charlotte Menné Bonefeld et al.
Contact dermatitis, 65(6), 336-342 (2011-07-20)
Perfumes are complex mixtures composed of many fragrance ingredients, many of which are known to be only weak allergens when tested individually. It is therefore surprising that fragrance contact allergy is one of the most common forms of contact allergy.
Esra Fındık et al.
European journal of medicinal chemistry, 46(9), 4618-4624 (2011-08-17)
We are attempting to develop the novel phenolic synthetic antioxidants aimed at retarding the effects of free radicals and oxidants. The phenolic compounds (7-12) were synthesized by Friedel-Crafts alkylation of isoeugenol (1) and phenol derivatives (2-6) and their structures were
Valentina Galbiati et al.
Archives of toxicology, 86(2), 239-248 (2011-10-05)
We previously demonstrated in the human promyelocytic cell line THP-1 that all allergens tested, with the exception of the prohapten isoeugenol, induced a dose-related release of interleukin-8 (IL-8). In the present study, we investigated whether this abnormal behavior was regulated
Elvira M Gaspar et al.
Journal of the science of food and agriculture, 99(4), 1668-1674 (2018-09-11)
Food irradiation is a widely used technique for improving the safety and shelf life of foods, including most spices. However, growing concerns by consumers about this technique require further investigation on the effects of radiation, both on the safety of
Yu-Ping Cao et al.
Immunopharmacology and immunotoxicology, 34(2), 196-204 (2011-07-05)
Many attempts have been made to develop in vitro sensitization tests that employ dendritic cells (DCs), DC-like cell lines or keratinocytes. The aim of the present investigation was to establish a co-culture of THP-1 cells and keratinocytes for evaluation of
Morten Hyldgaard et al.
International journal of food microbiology, 215, 131-142 (2015-10-05)
Proliferation of microbial population on fresh poultry meat over time elicits spoilage when reaching unacceptable levels, during which process slime production, microorganism colony formation, negative organoleptic impact and meat structure change are observed. Spoilage organisms in raw meat, especially Gram-negative
Ji-Young Ryu et al.
Bioscience, biotechnology, and biochemistry, 76(10), 1891-1896 (2012-10-11)
Vanillin is one of the most valuable compounds in the flavoring and fragrance industries, and many attempts to produce natural vanillin have been made in recent years. Isoeugenol monooxygenase (Iem) converts the phenylpropanoid compound isoeugenol to vanillin. In Pseudomonas nitroreducens
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