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Daniel Melles et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 913-914, 106-112 (2013-01-05)
Skin sensitization is initiated by the modification of proteins located in the skin. After oxidative activation, eugenol and isoeugenol have the potential to modify skin proteins and therefore cause sensitization processes. Despite their known skin sensitizing properties, they are of
Toshiki Furuya et al.
Chembiochem : a European journal of chemical biology, 15(15), 2248-2254 (2014-08-29)
Vanillin is one of the most widely used flavor compounds in the world as well as a promising versatile building block. The biotechnological production of vanillin from plant-derived ferulic acid has attracted much attention as a new alternative to chemical
Aurélie Frankart et al.
Archives of dermatological research, 304(4), 289-303 (2012-01-25)
Models of reconstructed human epidermis (RHE) holding proliferating and fully differentiated cultured keratinocytes allow in vitro investigation of early molecular and cellular epidermal events during the complex response of keratinocytes at the onset of allergic contact dermatitis (ACD) or sensitization.
National Toxicology Program technical report series, (551)(551), 1-178 (2011-03-05)
Isoeugenol is one of several structurally similar phenylpropenoid compounds produced by plants. It has been extracted from calamus, savory, basil, ylang-ylang, clove, tuberose, jonquil, nutmeg, tobacco, sandalwood, dill seed, mace, gardenia, petunia, and other flowers. Isoeugenol can also be produced
J Krupa et al.
The journal of physical chemistry. B, 116(36), 11148-11158 (2012-07-26)
In situ photochemical transformations of monomers of 2-methoxy-4-(prop-1-enyl)phenol (isoeugenol) and 2-methoxy-4-(prop-2-enyl)phenol (eugenol) isolated in low temperature matrices were induced by tunable UV laser light, and the progress of the reactions was followed by FTIR spectroscopy. Conformer-selective E ↔ Z geometrical
Gurpreet Kaur et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 50(8), 2689-2695 (2012-05-23)
Isoeugenol, a component of clover oil, possesses potent anti-inflammatory and antioxidant activity. In the present study, we investigated the effect on experimentally induced adjuvant arthritis in rats. Induction of arthritis in adjuvant exposed rats was confirmed by appearance of several
Esra Fındık et al.
European journal of medicinal chemistry, 46(9), 4618-4624 (2011-08-17)
We are attempting to develop the novel phenolic synthetic antioxidants aimed at retarding the effects of free radicals and oxidants. The phenolic compounds (7-12) were synthesized by Friedel-Crafts alkylation of isoeugenol (1) and phenol derivatives (2-6) and their structures were
Valentina Galbiati et al.
Archives of toxicology, 86(2), 239-248 (2011-10-05)
We previously demonstrated in the human promyelocytic cell line THP-1 that all allergens tested, with the exception of the prohapten isoeugenol, induced a dose-related release of interleukin-8 (IL-8). In the present study, we investigated whether this abnormal behavior was regulated
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